中国优食蚜蝇属六新种记述(双翅目:食蚜蝇科)

本文记述我国优食蚜蝇属Eupeodes(syn.Metasyrphus)6新种。属下分类采取Vockeroth(1969,1986)的分亚属概念。文中记述的新种全部属于优食蚜蝇亚属Eupeodes(s.str.),并将本亚属内其他5种食蚜蝇重新组合,同时对有些种的中名也作了相应修改。新种模式标本保存于上海农学院。 新组合种:1.硕翅优食蚜蝇Eupeodes(Eupeodes)macropterus(Thomson),1869     

Anti-idiotypic antibodies as probes of cell surface receptors

Summary Anti-idiotypic antibodies have proven to have unique applications as probes in both functional and biochemical studies of cell surface receptors. Anti-idiotypic receptor antibodies have been prepared to antibodies which bind to purified ligand, as in the case of insulin, retinol-binding protein, the mammalian reovirus receptor, and the neutrophil chemotatic receptor, and to natural ligand analogs, such as the beta-adrenergic antagonist alprenolol. These systems have documented the usefulness of anti-idiotypic antibodies in the quantitation and modulation of specific membrane receptors on a variety of cell types. Anti-idotypic antibodies have also been utilized for the isolation of specific membrane receptors, e.g., reovirus and B-1 H globulin receptors. Some anti-idiotypic receptor antibodies, e.g., insulin and reovirus systems, have been shown to mimic the physiological properties of ligand upon binding to cellular receptors. These antibodies enable a new dimension of both receptor based cellular studies and therapeutic regimens. This review focuses on the past use of anti-idiotypic antibodies as probes of cell surface receptors, and on the methodologies required for the successful application of anti-idiotypic antibodies for use in further membrane receptor studies, and of the genes which encode and regulate these receptors. We also discuss the use of anti-idiotypic antibodies in the understanding of and therapeutic approach to receptor related diseases.Dr. Gaulton received the NRSA Viral Oncology Training Grant t# CA 09031.     

Answering a century old riddle: brachydactyly type Al

In 1903, Farabee analyzed the heredity of the human digital malformation, brachydactyly, the first recorded disorder of the autosomal dominant Mendelian trait. In 1951, Bell classified this type of brachydactyly as type A1 (BDA1). Over 100 cases from different ethnic groups have so far been reported. However, the real breakthrough in identifying the cause of BDA1 has only taken place in the last few years with the progress of the mapping and identification of one of the genes responsible for this disorder, thus providing an answer for a century old riddle. In this article, we attempt to review the current state of knowledge on the genetic features of BDA1 with its century-old history and signalling pathway of IHH, and also discuss genotype-phenotype correlation not only of BDA1, but also of all types of brachydactyly.     

医院设备的接地方式探讨

本文根据某些医院设备接地方式上存在的问题提出了十条改进意见，并建议制订了《医院设备接地方式指南》强制性规范，改善防电击安全性。