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71.
Shaik Hajira Jillela Santhosh Vijitha Sanjay Janrao Dhoble Borelli Deva Prasad Raju Busireddy Sudhakar Reddy 《Luminescence》2024,39(1):e4612
Red and green rare-earth ion (RE3+) (RE = Eu, Tb):MgLa2V2O9 micro-powder phosphors were produced utilizing a standard solid-state chemical process. The X-ray diffraction examination performed on the phosphors showed that they were crystalline and had a monoclinic structure. The particles grouped together, as shown in the scanning electron microscopy (SEM) images. Powder phosphors were examined using a variety of spectroscopic techniques, including photoluminescence (PL), Fourier-transform infrared, and energy dispersive X-ray spectroscopy. Brilliant red emission at 615 nm (5D0 → 7F2) having an excitation wavelength (λexci) of 396 nm (7F0 → 5L6) and green emission at 545 nm (5D4 → 7F5) having an λexci = 316 nm (5D4 → 7F2) have both been seen in the emission spectra of Tb3+:MgLa2V2O9 nano-phosphors. The emission mechanism that is raised in Eu3+:MgLa2V2O9 and Tb3+:MgLa2V2O9 powder phosphors has been explained in an energy level diagram. 相似文献
72.
Chatla Srinivas M. Janaki Ramaiah A. Lavanya Suresh Yerramsetty P. B Kavi Kishor Shaik Anver Basha Ahmed Kamal Utpal Bhadra Manika-Pal Bhadra 《PloS one》2015,10(11)
Tumor microenvironment play role in angiogenesis and carcinogenesis. Etoposide, a known topoisomerase II inhibitor induces DNA damage resulting in cell cycle arrest. We developed a novel Etoposide analogue, Quinazolino-4β-amidopodophyllotoxin (C-10) that show better efficacy in regulating cell proliferation and angiogenesis. We evaluated its role on expression of microRNAs-15, 16, 17 and 221 and its targets Bcl-2, STAT3 and VEGF that dictate cell proliferation and angiogenesis. Docking studies clearly demonstrated the binding of Etoposide and C-10 to STAT3. We conclude that combination of Etoposide or C-10 with miR-15, 16, 17 and 221 as a new approach to induce apoptosis and control angiogenesis in breast cancer. 相似文献
73.
Hui Liu Shaik Althaf Hussain Daoud Ali Suliman Yousef Al Omar Umeshareen Shaik Hamzah Abdullatif Hajis Alghamdi Narendra Maddu 《Saudi Journal of Biological Sciences》2020,27(12):3669-3675
The effects of tetramethrin and prallethrin exposure on plasma total proteins, free amino acids, albumins, urea, urea nitrogen, uric acid, creatinine were tested. Serum SGOT, SGPT and lipid profile, antioxidants super oxide dismutase (SOD), catalase, GSH, G-Px, phospholipids, cholesterol, C/P ratio in membranes of erythrocyte and membrane fluidity were analyzed. The reason of the study were analyzed to examine the possessions of mosquito repellent pyrethroid (MRP) based compounds tetramethrin and prallethrin exposure on plasma profile, antioxidant status of erythrocyte membrane, membrane fluidity in male Wistar rats. We tested chronically for three months exposure every day (continuously for 8–10 h per day by inhalation) of tetramethrin and prallethrin markedly available (MRP) repellents treated on male Wistar rats. Our results confirmed that tetrarmethrin and prallethrin treatment effect of plasma profile alterations, and lipid homeostasis mechanism in Red Blood cells (RBCs). Tetramethrin and prallethrin treatment significantly increased in erythrocyte membrane phospholipids and decreased levels of cholesterol with no change of protein content, increased C/P ration levels. Inhalation of tetramethrin and prallethrin stimulate plasma biophysical and biochemical modify SGOT, SGPT, erythrocyte membrane cholesterol and phospholipid levels, individual phospholipids and membrane fluidity of exposure rats compared to controls. 相似文献
74.
Digpal Singh Gour Jyotsna Bhagavatula Maradani Bhavanishankar Patlolla Anuradha Reddy Jaya A. Gupta Mriganka Shekhar Sarkar Shaik Mohammed Hussain Segu Harika Ravinder Gulia Sisinthy Shivaji 《PloS one》2013,8(7)
Background
Tiger populations are dwindling rapidly making it increasingly difficult to study their dispersal and mating behaviour in the wild, more so tiger being a secretive and solitary carnivore.Methods
We used non-invasively obtained genetic data to establish the presence of 28 tigers, 22 females and 6 males, within the core area of Pench tiger reserve, Madhya Pradesh. This data was evaluated along with spatial autocorrelation and relatedness analyses to understand patterns of dispersal and philopatry in tigers within this well-managed and healthy tiger habitat in India.Results
We established male-biased dispersal and female philopatry in tigers and reiterated this finding with multiple analyses. Females show positive correlation up to 7 kms (which corresponds to an area of approximately 160 km2) however this correlation is significantly positive only upto 4 kms, or 50 km2 (r = 0.129, p<0.0125). Males do not exhibit any significant correlation in any of the distance classes within the forest (upto 300 km2). We also show evidence of female dispersal upto 26 kms in this landscape.Conclusions
Animal movements are important for fitness, reproductive success, genetic diversity and gene exchange among populations. In light of the current endangered status of tigers in the world, this study will help us understand tiger behavior and movement. Our findings also have important implications for better management of habitats and interconnecting corridors to save this charismatic species. 相似文献75.
76.
Pamidimarri?D.?V.?N.?SudheerEmail author Shaik?G.?Mastan Hifzur?Rahman Ch.?Ravi Prakash Sweta?Singh Muppala?P.?ReddyEmail author 《Molecular biology reports》2011,38(2):1383-1388
The present investigation was undertaken with an aim to check the ability of cross species amplification of microsatellite
markers isolated from Jatropha curcas—a renewable source of biodiesel to deduce the generic relationship with its six sister taxa (J. glandulifera, J. gossypifolia, J. integerrima, J. multifida, J. podagrica, and J. tanjorensis). Out of the 49 markers checked 31 markers showed cross species amplification in all the species studied. JCDS-30, JCDS-69,
JCDS-26, JCMS-13 and JCMS-21 amplified in J. curcas. However, these markers did not show any cross species amplification. Overall percentage of polymorphism (PP) among the species
studied was 38% and the mean genetic similarity (GS) was found to be 0.86. The highest PP (24) and least GS (0.76) was found
between J. curcas/J. podagrica and J. curcas/J. multifida and least PP (4.44) and highest GS (0.96) was found between J. integerrima/J. tanjorensis. Dendrogram analysis showed good congruence to RAPD and AFLP than nrDNA ITS data reported earlier. The characterized microsatellites
will pave way for intraspecies molecular characterization which can be further utilized in species differentiation, molecular
identification, characterization of interspecific hybrids, exploitation of genetic resource management and genetic improvement
of the species through marker assisted breeding for economically important traits. 相似文献
77.
Govender Algasan Shaik Rehana Pillay Balakrishna 《World journal of microbiology & biotechnology》2011,27(5):1217-1224
1,2-dichloroethane (DCA) is a toxic synthetic haloalkane produced annually in excess of 20 billion tons. Five bacterial isolates
capable of complete mineralization of DCA have recently been isolated from wastewater treatment facilities in South Africa.
Pulsed field gel electrophoresis (PFGE) and random amplification of polymorphic DNA (RAPD) analysis were employed in this
study to identify phylogenetic differences between these closely-related bacteria. Analysis of the 16S rDNA sequences of the
selected isolates revealed similarities to previously characterised isolates of Ancylobacter aquaticus. It has been previously
shown that all isolates follow the same catabolic pathway and possess an identical hydrolytic dehalogenase (DhlA) involved
in the initial carbonchlorine bond cleavage. Analysis of homology matrices deduced from RAPD and restriction profiles, constructed
using the GelCompar software package, revealed that although some of the isolates possessed identical profiles using one primer
or restriction endonuclease, differences were observed when a different primer was used. Furthermore, the results obtained
indicate that the previously characterised isolate A. aquaticus AD25 is significantly different from the isolates used in
this study. PFGE was also able to show that isolates of A. aquaticus do not possess the 200 kb plasmid containing the hydrolytic
dehalogenase gene previously identified in the DCA-degrading bacterium Xanthobacter autotrophicus GJ10. This study has been
able to demonstrate that RAPD and PFGE analysis are suitable molecular tools for the differentiation of closely-related A.
aquaticus isolates and may be routinely used in the differentiation of environmentally important bacteria. 相似文献
78.
Raju BC Rao RN Suman P Yogeeswari P Sriram D Shaik TB Kalivendi SV 《Bioorganic & medicinal chemistry letters》2011,21(10):2855-2859
Series of 4H-chromen-1,2,3,4-tetrahydropyrimidine-5-carboxylate derivatives 7a-7zb, 8a-8d and 9a-9d were synthesized and screened for their in vitro anti-mycobacterial activity against Mycobacterium tuberculosis H37Rv (MTB) and cytotoxicity against three human cancer cell lines including A549, SK-N-SH and HeLa. The results indicate that six compounds are more potent and 7za is most effective anti-mycobacterial derivative compared to the standard drugs Ethambutol and Ciprofloxacin. However, 12 compounds exhibited cytotoxicity against human neuroblastoma cell line; amongst them the compound 7v is most effective compared to the standard drug Doxorubicin. This is the first report assigning in vitro anti-mycobacterial, anticancer and structure-activity relationship for this new class of 4H-chromen-1,2,3,4-tetrahydropyrimidine-5-carboxylates. 相似文献
79.
Althaf Hussain Shaik Shajidha Ruksar Shaik Abdul Saheer Shaik Ali Daoud Manoharadas Salim Lakshmi Devi Kodidhela 《Saudi Journal of Biological Sciences》2021,28(4):2575-2580
ObjectiveThis research designed to analyze the in vivo and in silico ameliorative action of maslinic acid (MA) and gallic acid (GA) on reactive oxygen species generating enzyme xanthine oxidase (XO) in isoprenaline or isoproterenol (ISO) induced myocardial infarcted rats.MethodsAlbino Wistar rats were categorized into four groups with eight rats in each group. A dose of 15 mg/kg of MA and GA were pretreated to each MA and GA groups for seven days. A dose of 85 mg/kg of ISO administered to the ISO group along with MA and GA groups except normal group on two consecutive days of pretreatment. All animals sacrificed and the heart tissues were collected for the analysis of XO. The in silico molecular docking analysis of the compounds MA and GA with XO was analyzed by using Gold 3.0.1 software.ResultsXO enzyme levels were significantly increased in the heart homogenate of ISO administered rats when compared to normal rats. Pretreatment of MA and GA to ISO treated rats significantly brought XO enzyme to the near normal levels which indicate the protective action of MA and GA against myocardial necrosis. The in vivo results were further supported by the in silico molecular docking study which revealed the inhibition of XO enzyme by the formation of enzyme and ligand complex with the compounds MA and GA.ConclusionMA and GA compounds manifested the ameliorative effect against ISO administrated myocardial necrosis by inhibiting the free radical generating enzyme XO which is evidenced by both in vivo and in silico studies. 相似文献
80.
Predicting the Open‐Circuit Voltage of CH3NH3PbI3 Perovskite Solar Cells Using Electroluminescence and Photovoltaic Quantum Efficiency Spectra: the Role of Radiative and Non‐Radiative Recombination 下载免费PDF全文