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Ion composition and osmolarity of Caspian Sea ctenophore, Mnemiopsis leidyi, in different salinities
Maryam Yazdani Foshtomi Behrooz Abtahi Mehrshad Taheri 《Journal of experimental marine biology and ecology》2007,352(1):28-34
The aim was to study osmotic and ionic regulation in alien ctenophore, Mnemiopsis leidyi (total length of 1.5-3 cm), acclimated gradually to artificial sea water of different salinities (8, 13, 18 and 23 ppt) in laboratory conditions (24 ± 2 °C) with the salt composition and proportion of the Caspian Sea. Results showed that this species is hyper-osmoconformer (maintaining internal osmolarity 2-22 mOsmol l− 1 above external) in non-lethal salinities ranging from 8 to 23 ppt. The results of ionic regulatory investigations revealed that this species can regulate Ca2+ and SO42− so that the concentration of Ca2+ in the internal fluid and SO42− in the external fluid were significantly more in 8 and 13 ppt, respectively. No regulation was observed about other ions such as Cl−, Mg2+ and K+ in the mentioned salinities. 相似文献
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Tina Nafarieh Mojgan Bandehpour Ali Hashemi Sodabeh Taheri Vahid Yardel Hamidreza Jamaati Seyed Mahdi Moosavi Nariman Mosaffa 《World journal of microbiology & biotechnology》2017,33(10):189
Nosocomial infections with a bacterial origin are considered one of the most dangerous threats to global health. Among the causes of these infections, Acinetobacter baumannii is playing a significant role, and the present study aimed? to determine the immunogenic proteins of this bacteria. Clinical isolates of A. baumannii were obtained from positive sputum cultures of intensive care unit (ICU) patients confirmed by Polymerase chain reaction (PCR) of the OXA-51 gene, and sera was obtained from 20 colonized patients. In addition, 20 and 30 serum samples were collected from ICU nurses and healthy controls, respectively. All the samples were screened in the presence of antibodies against A. baumannii by enzyme-linked immunosorbent assay (ELISA). IgG purified from the serum samples by affinity chromatography was used to isolate the bacteria by the Magnetic-activated cell sorting (MACS) procedure. After the bacteria were cultured, the identified antigen proteins were studied by western blotting and Mass spectrometry (MS). The MS results were analyzed with MASCOT software and revealed a 35 KD protein, which corresponds to outer membrane protein A (OmpA) of A. baumannii, a 25 KD band, which is a carbapenem-associated resistance protein precursor, and a 60 KD protein band, identified as a stress-induced bacterial acidophilic repeat motif protein. According to the properties of immunogen antigens and bio informatics tools, the outer membrane proteins (OMPs) can be used as a vaccine candidate in animal models. 相似文献
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Elham Ghadami Novin Nikbakhsh Sadegh Fattahi Mohadeseh Kosari-Monfared Mohammad Ranaee Hassan Taheri Fatemeh Amjadi-Moheb Gholamali Godazandeh Shahryar Shafaei Anahita Nosrati Maryam Pilehchian Langroudi Ali Akbar Samadani Galia Amirbozorgi Vahideh Mirnia Haleh Akhavan-Niaki 《Journal of cellular physiology》2019,234(4):4115-4124
Gastric cancer (GC) is one of the most common causes of cancer-related death in the world, with multiple genetic and epigenetic alterations involved in disease development. CYLD tumor suppressor gene encodes a multifunctional deubiquitinase which negatively regulates various signaling pathways. Deregulation of this gene has been found in different types of cancer. This study aimed to evaluate for the first time the CpG island methylation pattern of CYLD gene promoter, and its expression level in gastric adenocarcinoma. CYLD messenger RNA expression and promoter methylation in 53 tumoral and their non-neoplastic counterpart tissues were assessed using quantitative polymerase chain reaction and bisulfite sequencing. Also, we investigated the impacts of the infectious agents including Helicobacter pylori (H. pylori), EBV, and CMV on CYLD expression and promoter methylation in GC. Results showed that the expression level of CYLD was downregulated in GC, and was significantly associated with gender (female), patient’s age (<60), high grade, and no lymph-node metastasis (p = 0.001, 0.002, 0.03, and 0.003, respectively). Among the 31 analyzed CpG sites located in about 600 bp region within the promoter, two CpG sites were hypermethylated in GC tissues. We also found a significant inverse association between DNA promoter methylation and CYLD expression (p = 0.02). Furthermore, a direct association between H. pylori, EBV, and CMV infections with hypermethylation and reduced CYLD expression was observed (p = 0.04, 0.03, and 0.03, respectively). Our findings indicate that CYLD is downregulated in GC. Infectious agents may influence CYLD expression. 相似文献
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Omid Reza Tamtaji Mojtaba Naderi Taheri Fahimeh Notghi Reza Alipoor Reihanesadat Bouzari Zatollah Asemi 《Journal of cellular biochemistry》2019,120(8):12156-12166
Among the progressive neurodegenerative disorders, Parkinson's disease (PD) is the second most common. Different factors have critical role in pathophysiology of PD such as apoptosis pathways, inflammatory cytokines, oxidative stress, and neurotransmitters and its receptors abnormalities. Acupuncture and electroacupuncture were considered as nondrug therapies for PD. Although numerous studies has been conducted for assessing the mechanism underlying electroacupuncture and acupuncture, various principal aspects of these treatment procedures remain not well-known. There have also been few investigations on the molecular mechanism of acupuncture and electroacupuncture therapy effects in PD. This review evaluates the effects of electroacupuncture and acupuncture on the molecular mechanism in PD. 相似文献
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Elyasi Nahid Taheri Kimia Karimi Narooei Keivan Taheri Ali Karimi 《Biomechanics and modeling in mechanobiology》2017,16(3):1077-1093
Biomechanics and Modeling in Mechanobiology - In this research, the nonlinear elastic behavior of human extensor apparatus was investigated. To this goal, firstly the best material parameters of... 相似文献
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