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811.
Ambrin Fatima Jan Hoeber Jens Schuster Eriko Koshimizu Carolina Maya-Gonzalez Boris Keren Cyril Mignot Talia Akram Zafar Ali Satoko Miyatake Junpei Tanigawa Takayoshi Koike Mitsuhiro Kato Yoshiko Murakami Uzma Abdullah Muhammad Akhtar Ali Rein Fadoul Loora Laan Casimiro Castillejo-Lpez Maarika Liik Zhe Jin Bryndis Birnir Naomichi Matsumoto Shahid M. Baig Joakim Klar Niklas Dahl 《American journal of human genetics》2022,109(3):542-546
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The importance of rare species: a trait‐based assessment of rare species contributions to functional diversity and possible ecosystem function in tall‐grass prairies
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Meha Jain Dan F.B. Flynn Case M. Prager Georgia M. Hart Caroline M. DeVan Farshid S. Ahrestani Matthew I. Palmer Daniel E. Bunker Johannes M.H. Knops Claire F. Jouseau Shahid Naeem 《Ecology and evolution》2014,4(1):104-112
The majority of species in ecosystems are rare, but the ecosystem consequences of losing rare species are poorly known. To understand how rare species may influence ecosystem functioning, this study quantifies the contribution of species based on their relative level of rarity to community functional diversity using a trait‐based approach. Given that rarity can be defined in several different ways, we use four different definitions of rarity: abundance (mean and maximum), geographic range, and habitat specificity. We find that rarer species contribute to functional diversity when rarity is defined by maximum abundance, geographic range, and habitat specificity. However, rarer species are functionally redundant when rarity is defined by mean abundance. Furthermore, when using abundance‐weighted analyses, we find that rare species typically contribute significantly less to functional diversity than common species due to their low abundances. These results suggest that rare species have the potential to play an important role in ecosystem functioning, either by offering novel contributions to functional diversity or via functional redundancy depending on how rare species are defined. Yet, these contributions are likely to be greatest if the abundance of rare species increases due to environmental change. We argue that given the paucity of data on rare species, understanding the contribution of rare species to community functional diversity is an important first step to understanding the potential role of rare species in ecosystem functioning. 相似文献
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Bilal Ahmad Ganaie Mir Shahid Auqib Rashid Tabassum Ara Javid Ahmad Banday Fayaz Malik Bilal A. Bhat 《化学与生物多样性》2021,18(10):e2100292
A series of rationally designed platanic acid-based compounds derived from naturally occurring betulinic acid were synthesized through a sequence of Lemieux-Johnson oxidation and Aldol condensation reaction. All the compounds were screened for cytotoxicity against a panel of human cancer and normal cell lines using MTT assay. From the biological data, it was observed that some of these semi-synthetic congeners exhibited potent biological profiles compared to platanic acid. One of the compounds with the p-tolyl substitution was found to be most active in this study, and its cytotoxicity against two of the cell lines, MDA-MB 231 and A-549 were in tune with the standard compound, 5-fluorouracil. 相似文献
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Zhang Liusheng Shivute Fimanekeni Ndaitavela Shahid Muhammad Qasim Kamara Nabieu Wu Jinwen Liu Xiangdong 《Plant Cell, Tissue and Organ Culture》2019,139(3):577-587
Plant Cell, Tissue and Organ Culture (PCTOC) - Oryza alta Swallen is an important germplasm for rice resistance breeding; however, its CCDD genome (2n?=?48) resulted in low crossability... 相似文献
819.
Phagocytosis plays a key role in nutrient uptake and virulence of the protist parasite Entamoeba histolytica. Phagosomes have been characterized by proteomics, and their maturation in the cells has been studied. However, there is so far not much understanding about initiation of phagocytosis and formation of phagosomes at the molecular level. Our group has been studying initiation of phagocytosis and formation of phagosomes in E. histolytica, and have described some of the molecules that play key roles in the process. Here we show the involvement of EhAK1, an alpha kinase and a SH3 domain containing protein in the pathway that leads to formation of phagosomes using red blood cell as ligand particle. A number of approaches, such as proteomics, biochemical, confocal imaging using specific antibodies or GFP tagged molecules, expression down regulation by antisense RNA, over expression of wild type and mutant proteins, were used to understand the role of EhAK1 in phagocytosis. EhAK1 was found in the phagocytic cups during the progression of cups, until closure of phagosomes, but not in the phagosomes themselves. It is recruited to the phagosomes through interaction with the calcium binding protein EhCaBP1. A reduction in phagocytosis was observed when EhAK1 was down regulated by antisense RNA, or by over expression of the kinase dead mutant. G-actin was identified as one of the major substrates of EhAK1. Phosphorylated actin preferentially accumulated at the phagocytic cups and over expression of a phosphorylation defective actin led to defects in phagocytosis. In conclusion, we describe an important component of the pathway that is initiated on attachment of red blood cells to E. histolytica cells. The main function of EhAK1 is to couple signalling events initiated after accumulation of EhC2PK to actin dynamics. 相似文献
820.
Jameel R. Al-Obaidi Norasfaliza Rahmad Nursyuhaida Mohd Hanafi Mohammed Farouq Halabi Abdulrahman A. Al-Soqeer 《Acta Physiologiae Plantarum》2017,39(8):179
Jojoba is a dioecious shrub with female and male flowers in separated individuals. The plant native to North and Central American deserts, it’s cultivated in many other places worldwide for its valuable liquid wax. The male-biased ratio in cultivated jojoba affects the yield. To develop protein molecular markers for early gender differentiation, comparative proteomic study been conducted on male and female leaves. Using gel-based proteomic, 45 proteins were identified representing 19 different proteins with 18 known functions. The identified proteins were involved in photosynthesis, energy, metabolism and the respond to biotic and abiotic stress. Ribulose-1,5-bisphosphate carboxylase (Rubisco) and ATP synthase were the most abundant proteins in both male and female of jojoba leaves, both were upregulated in male compared to female. Both proteins have the potential to serve as protein biomarkers for early differentiation between male and female in jojoba plant. These results could help in better understanding the molecular mechanism of gender differentiation in jojoba. 相似文献