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81.
Syed Shakeel Ahmad Zafar A. Reshi Manzoor A. Shah Irfan Rashid Roshan Ara Syed M. A. Andrabi 《International journal of phytoremediation》2014,16(12):1183-1191
Heavy metals are an important class of pollutants with both lethal and sublethal effects on organisms. Wetlands are cheap natural alternatives for removal of heavy metals from soils; however, wetland plants vary greatly in their degree of metal uptake. Hokersar wetland, a Ramsar site of Kashmir Himalaya, India is a game reserve of international importance that provides suitable habitat for resident birds and an excellent stopover point for migratory birds visiting from Palaearctic breeding grounds in Central Asia, China, N-Europe and Siberia. The toxicity of chronic dietary metal exposure in birds may have adverse reproductive effects which include decreased egg production, decreased hatchability, and increased hatchling mortality. Thus, the present study aimed to assess the heavy metal sequestration capability of one of the most common wetland plant species Phragmites australis in Hokersar wetland. The accumulation of the different elements was in order of Al > Mn > Ba > Zn > Cu > Pb > Mo > Co > Cr > Cd > Ni. Translocation factor, i.e. ratio of shoot to root metal concentration revealed that metals were largely retained in the roots of P. australis, thus reducing the supply of metals to avifauna and preventing their bio-accumulation. 相似文献
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Suozhen Hui Huijuan Li Amos Musyoki Mawia Liang Zhou Jinyang Cai Shakeel Ahmad Changkai Lai Jingxin Wang Guiai Jiao Lihong Xie Gaoneng Shao Zhonghua Sheng Shaoqing Tang Jianlong Wang Xiangjin Wei Shikai Hu Peisong Hu 《Plant biotechnology journal》2022,20(1):59-74
Aroma is a key grain quality trait that directly influences the market price of rice globally. Loss of function of betaine aldehyde dehydrogenase 2 (OsBADH2) affects the biosynthesis of 2-acetyl-1-pyrroline (2-AP), which is responsible for aroma in fragrant rice. The current study was aimed at creating new alleles of BADH2 using CRISPR/Cas9 gene editing technology under the genetic background of the japonica Ningjing 1 (NJ1) and indica Huang Huazhan (HHZ) varieties. Sensory evaluation and analysis using headspace solid-phase microextraction gas chromatography–mass spectrometry (HS-SPME-GC-MS) showed that the grains of the four homozygous T1 lines with new alleles of BADH2 (nj1-cr BADH2-1, nj1-cr BADH2-2, hhz-cr BADH2-1 and hhz-cr BADH2-2) produced moderate fragrance and had significantly increased 2-AP content compared with wild-types. Moreover, there were no significant differences in the amylose content and gelatinization temperature among the four lines with new alleles of BADH2 to the wild-types. Thereafter, we crossed the HHZ background new alleles of BADH2 with CMS line Taonong 1A (TN1A) to produce a three-line hybrid variety B-Tao-You-Xiangzhan (BTYXZ) with increased grain aroma. The 2-AP content in grains of the improved BTYXZ-1 and BTYXZ-2 reached at 26.16 and 18.74 μg/kg, and the gel consistency of BTYXZ-1 and BTYXZ-2 increased significantly by 9.1% and 6.5%, respectively, compared with the wild-type Tao-You-Xiangzhan (TYXZ). However, the γ-aminobutyric acid (GABA) content in the improved three-line hybrid rice BTYXZ-1 (5.6 mg/100 g) and BTYXZ-2 (10.7 mg/100 g) was significantly lower than that of the TYXZ. These results demonstrated that CRISPR/Cas9 gene editing technology could be successfully utilized in improving aroma in non-fragrant japonica and indica varieties. In addition, the newly developed BADH2 alleles provided important genetic resources for grain aroma improvement in three-line hybrid rice. 相似文献
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Shafiq-un-Nabi S Shakeel F Talegaonkar S Ali J Baboota S Ahuja A Khar RK Ali M 《AAPS PharmSciTech》2007,8(2):E12-E17
Summary and Conclusion Ramipril nanoemulsion formulations were successfully prepared by the spontaneous emulsification method (titration method).
Sefsol 218 was selected as the oil phase for the development of the formulation on the basis of the solubility studies. The
differences in the droplet size between the formulations selected from the phase diagram was not statistically significant,
although the polydispersity was at a minimum for the formulation containing 20% oil, 27% Smix, and 53% vol/vol aqueous phase.
The droplet size was found to be 34.5 nm. Therefore, nanoemulsion, a multipurpose technology, can be exploited in drug delivery
for poorly soluble drugs. Nanoemulsions have a higher solubilization capacity than simple micellar solutions, and their thermodynamic
stability offers advantages over unstable dispersions, such as emulsions and suspensions, because they can be manufactured
with little energy input (heat or mixing) and have a long shelf life. This technical note explains the basis for calculation
and construction of pseudoternary phase diagrams and, most important, explains selection of the formulations from the phase
diagrams to avoid metastable formulations having minimum surfactant concentration in the least possible time.
Published: April 6, 2007 相似文献
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Susanna K. P. Lau Yun Feng Honglin Chen Hayes K. H. Luk Wei-Hong Yang Kenneth S. M. Li Yu-Zhen Zhang Yi Huang Zhi-Zhong Song Wang-Ngai Chow Rachel Y. Y. Fan Syed Shakeel Ahmed Hazel C. Yeung Carol S. F. Lam Jian-Piao Cai Samson S. Y. Wong Jasper F. W. Chan Kwok-Yung Yuen Hai-Lin Zhang Patrick C. Y. Woo 《Journal of virology》2015,89(20):10532-10547
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Identification and clinical characterization of Hermansky–Pudlak syndrome alleles in the Pakistani population 下载免费PDF全文
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