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351.
Metin Ozata Ismail Kurt Muhittin A. Serdar M. Emin Onde Ahmet Aydin Ahmet Corakci M. Ali Gundogan 《Biological trace element research》1997,57(1):9-17
Although the availability of thyroid cyst fluid is easy by fineneedle aspiration, less is known about the biochemical composition
of thyroid cyst fluid. The authors have, therefore, determined the biochemical composition of 18 benign thyroid cyst fluid
specimens. They found that the activities of aspartate aminotransferase (AST), lactate dehydrogenase (LDH), and the concentrations
of total protein, total bilirubin, and uric acid were highly increased in thyroid cyst fluid specimens when compared with
normal human serum specimens. The concentrations of glucose, cholesterol, and triglycerides in cyst fluid were within normal
serum limits. Selenium (Se) concentrations in most cyst fluids were low. Moreover, there was no correlation between Se and
other biochemical parameters. Protein electrophoresis of cyst fluid specimens yielded high concentrations of α1 and especially α2 globulin fractions indicating an inflammation. The concentrations or activities of biochemical analytes were not significantly
different in pure and mixed cysts. Those parameters were also not significantly different between cyst fluids of different
colors. The gross appearance of the fluid and the presence of certain biochemical analytes were consistent with a hemorrhagic
origin of most of the cyst fluid specimens. However, some biochemical markers indicate that autolysis or necrosis of thyroid
tissue may also contribute the composition of thyroid cyst fluid. The reason for lower Se concentration in the thyroid cyst
fluid may be the lower Se concentration in the Turkish population. These results also suggest that the fluid color or nature
of cyst, e.g., pure or mixed cyst, is not a main determinant of biochemical composition of benign thyroid cyst fluid. 相似文献
352.
We describe two rare cases of fibrous pseudotumor of the paratesticular region. In the first case, five nodules arising from the tunica albuginea of right testicle causing scrotal, enlargement raising after urinary tract infection were seen. In the second case, multiple nodules arising tunica albuginea, tunica vaginalis and epididymis raising after left varicocelectomy operation were observed. The histology showed a paucicellular fibroblastic proliferation of cells within a hyalinized collagenous fibrous stroma containing numerous thin-walled blood vessels accompanied by lymphocytes and plasma cells in tumor tissues in both cases. Tumors in both cases were successfully resected. After operation, both patients had an uneventful recovery without any complications. 相似文献
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356.
A method was developed for simultaneous quantification of urinary 1- and 2-naphthols, 3- and 9-phenanthrols and 1-pyrenol using gas chromatography with mass spectrometry (GC-MS). This method was applied to urine samples from coke oven workers (n =28) and controls (n =22) from Northern China. Geometric mean levels of urinary 1-naphthol (58.8 μg l-1), 2-naphthol (34.1 μg l-1), 3-phenanthrol (7.35 μg l-1), 9-phenanthrol (1.28 μg l-1) and 1-pyrenol (25.4 μg l-1) were significantly higher among coke oven workers than controls. All the substances tested were highest among top-of-oven workers, who had 15-fold higher 1-naphthol, eight-fold higher 2-naphthol and 20-fold higher 1-pyrenol levels compared with controls. Using multiple linear regression models, 72.5% of the variation in 1- and 2-naphthol and 82.8% of the variation in 1-pyrenol were explained by the concentration of naphthalene or pyrene in the urine, the work category and the smoking intensity. Cigarette consumption significantly contributed to levels of urinary 1-pyrenol and naphthols, particularly 2-naphthol. A negative relationship between work category and the ratio of naphthols/1-pyrenol was observed among smokers. Our results suggest that urinary naphthols and phenanthrols reflect polycyclic aromatic hydrocarbon (PAH) exposure as well as the widely used 1-pyrenol, and that interactions between cigarette smoking and PAH exposure result in different patterns of metabolism for individual PAHs. 相似文献
357.
The objectives of this research are the assessment of secondary effluents (SEs) quality by evaluating chemical parameters and biomarkers. For this purpose, MDA and GSH levels were determined by spectrofotometer. SOD, CAT, and GPX activities were determined by using ELISA kit in the groups of control and the groups exposed to SE. The level of MDA and the activities of SOD in Gammarus pulex vary depending on the exposure time. GSH levels and GSH-PX activities increased in G. pulex exposed to the effluent compared to the control during 24 h and 96 h. CAT activities were in SE group were found lower than the control in G. pulex during 24 h and 96 h. Current experimental results show that SOD, CAT, GPX activities, and GSH and MDA levels in G. pulex are sensitive and appropriate responses for assess the effects of anthropogenic contaminants on the aquatic ecosystems, particularly effluent complex mixtures. 相似文献
358.
Nuray Erkan İdil Can Tunçelli Özkan Özden Serdar Üren 《Zeitschrift fur angewandte Ichthyologie》2020,36(6):906-911
This study attempts to delineate the nutritional value and potential problem of toxic metal contamination in Sardinella maderensis (Lowe,1838) originating from Mauritanian fishery destined for regional common human consumption. Samples caught in Mauritania were delivered to Turkey by ship in 22 days in cold storage. Amino acids, fatty acids and toxic metal analyses of the samples were carried out by using a HPLC (High Performance Liquid Chromatograph), GC (Gas Chromatography) and a ICP-MS (Inductively Coupled Plasma-Mass Spectrometry), respectively. Overall, the range of total Saturated Fatty Acids (SFAs), Monounsaturated Fatty Acids (MUFAs) and Polyunsaturated Fatty Acids (PUFAs) were found to be 34.35%, 28.13% and 34.50%, respectively. In terms of Eicosapentaenoic acid (EPA)+Docosahexaenoic acid (DHA) levels were found to be in total 24.34%. Amino acids content such as glutamic acid, histidine, leucine and lysine were 1735.5, 1,409, 1,580 and 1,710.5 mg/100 g tissue, respectively. Toxic metal levels of Hg, Cd, As, Cr, Mn, Co were determined to reach values between 0.03–4.19 mg/kg. Athough the study is limited, it seems that results on the composition of fatty acids and amino acid, indicate the high nutritional value, well suited for human consumption in particular in terms of omega 3 and essential amino acids. 相似文献
359.
Jacob R. Leistico Priyanka Saini Christopher R. Futtner Miroslav Hejna Yasuhiro Omura Pritin N. Soni Poorva Sandlesh Magdy Milad Jian-Jun Wei Serdar Bulun J. Brandon Parker Grant D. Barish Jun S. Song Debabrata Chakravarti 《Cell reports》2021,34(13):108927
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360.
The kinetic properties of sheep brain glutathione reductase (GSSGR) were investigated. The enzyme showed Ping-Pong kinetics with double substrate inhibition in the forward direction. Km values for NADPH and GSSG were found to be 60.9 and 116.9 mumol/l, and Ki values were found to be 42.1 and 347.3 mumol/l, respectively. NADP+ inhibition at low fixed concentration of NADPH was mixed-type with a Ki of 281.5 mumol/l and alpha of 0.048. It is concluded that the enzyme shows a hybrid Ping-Pong-ordered branched mechanism. 相似文献