全文获取类型
收费全文 | 59篇 |
免费 | 2篇 |
专业分类
61篇 |
出版年
2021年 | 1篇 |
2019年 | 2篇 |
2017年 | 2篇 |
2015年 | 2篇 |
2014年 | 1篇 |
2013年 | 1篇 |
2011年 | 2篇 |
2007年 | 1篇 |
2006年 | 1篇 |
2005年 | 1篇 |
2004年 | 3篇 |
2001年 | 2篇 |
2000年 | 1篇 |
1998年 | 1篇 |
1996年 | 1篇 |
1993年 | 1篇 |
1991年 | 2篇 |
1990年 | 1篇 |
1986年 | 1篇 |
1985年 | 1篇 |
1984年 | 1篇 |
1983年 | 1篇 |
1982年 | 3篇 |
1981年 | 3篇 |
1978年 | 1篇 |
1977年 | 1篇 |
1974年 | 3篇 |
1973年 | 3篇 |
1972年 | 4篇 |
1970年 | 2篇 |
1969年 | 2篇 |
1968年 | 4篇 |
1967年 | 3篇 |
1966年 | 2篇 |
排序方式: 共有61条查询结果,搜索用时 15 毫秒
21.
Competition and herbivory are ubiquitous environmental challenges that affect most plants. We examined the influence of phenotypic responses to either competition or herbivory on the subsequent response of the plants to the other factor. The stem-elongation response of Chenopodium album to light competition attenuated its resistance to caterpillar herbivory in terms of herbivore mortality, but not in terms of growth of the survivors. Plant responses to herbivory did not affect subsequent responses to light competition. Thus, plants were largely able to express phenotypic plasticity (a proportional increase in the phenotype) following previous exposure to a different environmental factor. Although plants were able to express sequential plasticity, the final phenotype expressed was limited by exposure to previous environmental factors: induced resistance reduced plant height and stem elongation made plants more palatable to herbivores. Phenotypic plasticity in response to competition and herbivory may thus limit the subsequent expression of adaptive phenotypes. 相似文献
22.
Experimental Salmonellosis XI. Induction of Cellular Immunity and Formation of Antibody by Transfer Agent of Mouse Mononuclear Phagocytes 总被引:1,自引:0,他引:1 下载免费PDF全文
Susumu Mitsuhashi Kazuko Saito Nobutaka Osawa Satonori Kurashige 《Journal of bacteriology》1967,94(4):907-913
When mice were injected intraperitoneally with a ribonucleic acid (RNA) preparation extracted from the peritoneal mononuclear phagocytes (termed monocytes) of immunized mice, these macrophages developed cellular immunity and cellular antibodies. The peritoneal monocytes were obtained from normal mice and maintained in tissue culture bottles in a homogeneous cell population. When they were treated in vitro with an immune RNA preparation, they acquired cellular immunity, and cellular antibodies were detectable in such monocytes. These results suggest that the mononuclear phagocytic cell line constitutes a cell line responsible for antibody formation. 相似文献
23.
Ehlinger Claire Dartevelle Pauline Zaet Abdurraouf Kurashige Yoshihito Haïkel Youssef Metz-Boutigue Marie-Hélène Marban Céline 《International journal of peptide research and therapeutics》2019,25(4):1689-1689
International Journal of Peptide Research and Therapeutics - The article A New Combination with D?Cateslytin to Eradicate Root Canal Pathogens, written by Claire Ehlinger, Pauline Dartevelle,... 相似文献
24.
Zhonggang Feng Rie Takahashi Takao Nakamura Daisuke Sato Nobuyuki Shirasawa Ayako Nakayama Sakura Kurashige Tadashi Kosawada Tatsuo Kitajima Mitsuo Umezu 《In vitro cellular & developmental biology. Animal》2014,50(8):700-706
In this study, we investigated the expression of the pathway, SRF–microRNA-1/microRNA-133a–Hand2, in the Wistar rat embryonic ventricular cardiomyocytes under conventional monolayer culture. The morphological observation of the cultured cardiomyocytes and the mRNA expression levels of three vital constituent proteins, MLC-2v, N-cadherin, and connexin43, demonstrated the immaturity of these cultured cells, which was featured by less myofibril density, immature sarcomeric structure, and significantly lower mRNA expression of the three constituent proteins than those in neonatal ventricular samples. More importantly, results in this study suggest that the change of SRF–microRNA-1/microRNA-133a–Hand2 pathway results into the attenuation of the Hand2 repression in cultured cardiomyocytes. These outcomes are valuable to understand the cellular state as embryonic cardiomyocytes to be in vitro model and might be useful for the assessment of engineered cardiac tissue and cardiac differentiation of stem cells. 相似文献
25.
Banskota AH Nguyen NT Tezuka Y Le Tran Q Nobukawa T Kurashige Y Sasahara M Kadota S 《Life sciences》2004,74(22):2781-2792
The effects of secoisolariciresinol (1) and isotaxiresinol (2), two major lignans isolated from the wood of Taxus yunnanensis, on tumor necrosis factor-alpha (TNF-alpha)-dependent hepatic apoptosis induced by D-galactosamine (d-GalN)/lipopolysaccharide (LPS) were investigated in mice. Co-administration of d-GalN (700 mg/kg) and LPS (10 microg/kg) resulted in a typical hepatic apoptosis characterized by DNA fragmentation and the formation of apoptotic bodies. Serum glutamic pyruvic transaminase (sGPT) and glutamic oxaloacetic transaminase (sGOT) levels were also raised at 8 h after d-GalN/LPS intoxication due to a severe necrosis of hepatocytes. Pre-administration of 1 or 2 (50, 10 mg/kg, i.p.) 12 and 1 h before d-GalN/LPS significantly reduced DNA fragmentation and prevented chromatin condensation, apoptotic body formation and hepatitis. Pro-inflammatory cytokines such as TNF-alpha and interferon-gamma (IFN-gamma) secreted from LPS-activated macrophages are important mediators of hepatocyte apoptosis in this model. Pre-treatment with 1 or 2 significantly inhibited the elevation of serum TNF-alpha and IFN-gamma levels. In a separate experiment, both lignans had a significant dose-dependent protective effect on d-GalN/TNF-alpha-induced cell death in primary cultured mouse hepatocytes and TNF-alpha-mediated cell death in murine L929 fibrosarcoma cells. These results indicated that 1 and 2 prevent d-GalN/LPS-induced hepatic injury by inhibiting hepatocyte apoptosis through the blocking of TNF-alpha and IFN-gamma production by activated macrophages and direct inhibition of the apoptosis induced by TNF-alpha. 相似文献
26.
Nobutaka Osawa Satonori Kurashige Kazuko Saito Susumu Mitsuhashi 《Microbiology and immunology》1974,18(3):187-192
An immune ribonucleic acid (RNA) preparation was obtained from the spleens of mice immunized with a live vaccine of Salmonella enteritidis. When peritoneal macrophages were infected with S. enteritidis 116–54 which had been treated by mixed cultivation with the peritoneal exudate cells of mice previously treated with an immune RNA preparation, they showed cellular resistance against the infecting bacteria. According to the results described previously and those described in this article, it can be concluded that the cellular resistance against an infection with S. enteritidis is traceable to a cellular antibody (or antibodies) detected in macrophages of mice immunized with a live vaccine of the same organism or of mice treated in vivo (or in vitro) with an immune RNA preparation. 相似文献
27.
28.
Ribonucleic acid (immune RNA, iRNA) extracted from the spleens of mice immunized with heterologous red blood cells induced antigen-specific immunologic memory. The type of cells (T cells, B cells) which participate in immunologic memory induced with iRNA was investigated. Immune RNA-primed T cells cooperated with normal, iRNA-primed or antigen-primed B cells and induced a high IgM response. Immune RNA-primed B cells did not cooperate with normal T cells, but did with iRNA- or antigen-primed T cells. The activities of iRNA-primed T and B cells were antigen-specific. 相似文献
29.
30.
Yuji Miyamoto Yoshifumi Baba Yasuo Sakamoto Mayuko Ohuchi Ryuma Tokunaga Junji Kurashige Yukiharu Hiyoshi Shiro Iwagami Naoya Yoshida Masayuki Watanabe Hideo Baba 《PloS one》2015,10(6)