全文获取类型
收费全文 | 1080221篇 |
免费 | 125827篇 |
国内免费 | 1081篇 |
出版年
2016年 | 12484篇 |
2015年 | 18567篇 |
2014年 | 21667篇 |
2013年 | 30049篇 |
2012年 | 34437篇 |
2011年 | 34797篇 |
2010年 | 23521篇 |
2009年 | 21936篇 |
2008年 | 31483篇 |
2007年 | 32385篇 |
2006年 | 30480篇 |
2005年 | 29162篇 |
2004年 | 29147篇 |
2003年 | 27760篇 |
2002年 | 27075篇 |
2001年 | 44644篇 |
2000年 | 44946篇 |
1999年 | 36287篇 |
1998年 | 14257篇 |
1997年 | 14745篇 |
1996年 | 14109篇 |
1995年 | 13371篇 |
1994年 | 13056篇 |
1993年 | 12900篇 |
1992年 | 30877篇 |
1991年 | 30129篇 |
1990年 | 29786篇 |
1989年 | 28887篇 |
1988年 | 26676篇 |
1987年 | 25921篇 |
1986年 | 24051篇 |
1985年 | 24171篇 |
1984年 | 20120篇 |
1983年 | 17603篇 |
1982年 | 13901篇 |
1981年 | 12503篇 |
1980年 | 11810篇 |
1979年 | 19362篇 |
1978年 | 15723篇 |
1977年 | 14232篇 |
1976年 | 13418篇 |
1975年 | 14817篇 |
1974年 | 16082篇 |
1973年 | 15768篇 |
1972年 | 14182篇 |
1971年 | 13163篇 |
1970年 | 11233篇 |
1969年 | 10746篇 |
1968年 | 9670篇 |
1967年 | 8753篇 |
排序方式: 共有10000条查询结果,搜索用时 203 毫秒
951.
952.
953.
J. M. Warren 《Journal of human evolution》1974,3(6):445-454
The experimental literature on learning by Primate and non-Primate mammals is reviewed, with the aim of identifying peculiarly Primate features of learning. The evidence indicates that quantitative comparisons of learning by Primates and other mammals are intrinsically equivocal and uninformative because of the impossibility of equating experimental conditions for members of different species. The comparative results of early learning set studies were seriously misleading because the test conditions discriminated against representatives of species in which vision is not a dominant modality.Analyses of transfer between different learning tasks strongly suggest that rhesus macaques differ qualitatively from non-Primates like cats in that they develop generalized, trans-situationally valid response strategies during training on a particular problem which can facilitate learning in other situations. Non-Primate mammals appear not to develop such strategies under the same circumstances. There is also evidence that monkeys are more able than cats to discard previously learned strategies when they are no longer maximally profitable. 相似文献
954.
955.
Structure of the KcsA potassium channel from Streptomyces lividans: a site-directed spin labeling study of the second transmembrane segment. 总被引:3,自引:0,他引:3
KcsA is a prokaryotic potassium channel. The present study employs cysteine scanning mutagenesis and site-directed spin labeling to investigate the structure of the second transmembrane segment (residues 82-120) in functional tetrameric channels reconstituted in lipid bilayers. Spin-spin interactions are observed between nitroxide side chains at symmetry-related sites close to the 4-fold axis of symmetry. To aid in quantitative analysis of these interactions, a new diamagnetic analogue of the nitroxide side chain is used to prepare magnetically dilute samples with constant structure. Using constraints imposed by the spin-spin interactions, a packing model for this segment is deduced that is in excellent agreement with the recently reported crystal structure [Doyle, D., et al. (1998) Science 280, 69-77]. The relatively immobilized state of the nitroxide side chains suggests that the channel is rigid on the electron paramagnetic resonance time scale. Moreover, the poor sulfhydryl reactivity of the cysteine at many locations indicates that the channel is not subject to the low-frequency fluctuations that permit reaction of buried cysteines. At sites expected to be located in the pore, the accessibility of the side chains to collision with O(2) or nickel(II) ethylenediaminediacetate is low. This inaccessibility, together with the generally low mobility of the side chains throughout the sequence, makes it difficult to detect the presence of the pore based on these measurements. However, the presence of a solvated pore can be directly demonstrated using a polarity parameter deduced from the EPR spectra recorded at low temperature. These measurements also reveal the presence of a polarity gradient in the phospholipid bilayer. 相似文献
956.
957.
P Kischel L Stevens V Montel F Picquet Y Mounier 《Journal of applied physiology》2001,90(5):1825-1832
We examined the changes in functional properties of triceps brachii skinned fibers from monkeys flown aboard the BION 11 satellite for 14 days and after ground-based arm immobilization. The composition of myosin heavy chain (MHC) isoforms allowed the identification of pure fibers containing type I (slow) or type IIa (fast) MHC isoforms or hybrid fibers coexpressing predominantly slow (hybrid slow; HS) or fast (hybrid fast) MHC isoforms. The ratio of HS fibers to the whole slow population was higher after flight (28%) than in the control population (7%), and the number of fast fibers was increased (up to 86% in flight vs. 12% in control). Diameters and maximal tensions of slow fibers were decreased after flight. The tension-pCa curves of slow and fast fibers were modified, with a decrease in pCa threshold and an increase in steepness. The proper effect of microgravity was distinguishable from that of immobilization, which induced less marked slow-to-fast transitions (only 59% of fast fibers) and changed the tension-pCa relationships. 相似文献
958.
Genetically modified tobacco plants (Nicotiana tabacumSamsun)with antisense cinnamyl alcohol dehydrogenase DNA, produce secondaryxylem of a reduced tensile stiffness. These plants were grownalongside control plants. The stems of the plants were flexedor protected from flexing over a period of several weeks. Thetensile moduli and second moments of areas of the differenttissues inside the stems were measured and used to calculatethe bending stiffness of the plants. In tobacco, the cylinderof xylem was found to be the most important tissue in determiningthe bending stiffness of the plants. The thickness of the xylemtissue cylinder increased when plants were subjected to flexuralstimulation. This increased the bending stiffness of the stems.The response to mechanical stimulation was found to be correlatedwith tissue strain and the genetically modified plants wereable to exactly compensate for the reduced modulus of theirxylem tissue by increasing the thickness of the xylem tissuecylinder more than in control plants.Copyright 1999 Annals ofBotany Company. Tobacco plants, stem bending, xylem tissue, second moment of area, thigmomorphogenesis, mechanical strain. 相似文献
959.
960.
Detailed flow patterns in the nasal cavity. 总被引:9,自引:0,他引:9
The human nasal cavity filters and conditions inspired air while providing olfactory function. Detailed experimental study of nasal airflow patterns has been limited because of the complex geometry of the nasal cavity. In this work, particle image velocimetry was used to determine two-dimensional instantaneous velocity vector fields in parallel planes throughout a model of the nasal cavity that was subjected to a nonoscillatory flow rate of 125 ml/s. The model, which was fabricated from 26 computed tomography scans by using rapid prototyping techniques, is a scaled replica of a human right nasal cavity. The resulting vector plots show that the flow is laminar and regions of highest velocity are in the nasal valve and in the inferior airway. The relatively low flow in the olfactory region appears to protect the olfactory bulb from particulate pollutants. Low flows were also observed in the nasal meatuses, whose primary function has been the subject of debate. Comparison of sequentially recorded data suggests a steady flow. 相似文献