Effect of hyperthermia on growth of Ehrlich ascites tumor cells

Hyperthermic treatment at 43 degrees C suppressed the growth of Ehrlich ascites tumor (EAT) cells in vitro. Incubation of EAT cells at 43 degrees C for as little as 1.5 h totally abolished the transplantability of the tumor. At the same time, the rate of cellular glucose uptake, the density of glucose transporter on the cells as well as the extent of thymidine, uridine and leucine incorporation were significantly reduced.     

Olfactory coding by lepidopterous larvae

Extracellular electrophysiological recording from olfactory receptors in the antennae of tobacco hornworm larvae (Manduca sexta (Johan.)) has revealed that cells respond differentially to different odors by changing latency, rate of increase of frequency of firing, rate of adaptation, and alternation of frequency increase and decrease. The resulting temporal patterns of spike activity could function as a code to allow for discrimination among various plant odors.

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Zusammenfassung Extrazelluläre elektrophysiologische Erregungsableitungen von Geruchsrezeptoren in den Antennen von Tabakschwärmer-Raupen (Manduca sexta (Johan.)) ergaben, daß die Zellen auf verschiedene Duftstoffe unterschiedlich mit Änderung der Latenzzeit, der Zunahmerate der Erregungsfrequenz, der Anpassungsrate sowie der Änderung der Frequenz-Zunahme und-Abnahme reagieren. Die sich daraus ergebenden Zeitmuster der Spike-Aktivität könnten als Code dienen und so die Unterscheidung zwischen verschiedenen Pflanzendüften ermöglichen.

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This research was supported by National Science Foundation Grant GB-1472.     

Sex pheromones of the moth, Archips podana: isolation, identification and field evaluation of two synergistic geometrical isomers

By means of analytical and electroantennogram methods, cis-11-and trans-11-tetradecenyl acetate have been isolated and identified as the sex pheromones of the fruit tree tortrix moth, Archips podana. In contrast to the single compounds, mixtures in a ratio of about 1 : 1 are highly attractive to male moths in field experiments.     

Reaction of methyl β-d-glycero-l-manno-heptopyranoside with cyclohexanone: Synthesis of the 4- and 6-methyl ethers of d-glycero-l-manno-heptitol

Acid-catalysed condensation of methyl β-d-glycero-l-manno-heptopyranoside with cyclohexanone yielded an approximately 3:1 mixture of the 2,3:6,7- and 2,3:4,7-di-O-cyclohexylideneheptosides (1 and 2), which could be separated either as their benzoates (3 and 4) or as their methyl ethers (5 and 6). The latter compounds afforded the 4- and 6-methyl ethers (7 and 8) of d-glycero-l-manno-heptitol.