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111.
YOUNG‐JOON PARK SUJIN KIM AEREE KIM SEUNG‐YEON HA YOUNG‐MEE LEE BONG‐KYUNG SHIN HYUN‐JOO LEE SOOJIN PARK HAN‐KYEOM KIM 《Bioethics》2010,24(6):309-322
This study assessed the knowledge and perception of human biological materials (HBM) and biorepositories among three study groups in South Korea. The relationship between the knowledge and the perception among different groups was also examined by using factor and regression analyses. In a self‐reporting survey of 440 respondents, the expert group was found more likely to be knowledgeable and positively perceived than the others. Four factors emerged: Sale and Consent, Flexible Use, Self‐Confidence, and Korean Bioethics and Biosafety Action restriction perception. The results indicate that those who are well aware of the existence of biobanks were more positively inclined to receive the Sale and Consent perception. As a result of the need for high quality HBMs and the use of appropriate sampling procedures for every aspect of the collection and use process, the biorepository community should pay attention to ethical, legal, and policy issues. 相似文献
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In order to show the function of agricultural protection of biodiversity at the level of homegarden, comparative analysis was operated between 20 farmer households through random sampling and farmers recommended in Horqin Left Wing Real Banner Tongliao city Inner Mongolia Autonomous Region and 10 farmer households of the Han nationality in the neighborhood. Thirty sampling plots of homegardens are investigated. The result indicates there are 100 homegarden plants in Bashou village, 84 in Hariwusu livestock farm, and 87 in Gongjihao village. It involves the cultivated and wild vegetables, fruits, and plants used for ornamental, medicine and forage. The comparative analysis of species richness demonstrates, among these villages the species richness of Bashou village is highest, while Hariwusu livestock farm is lowest. The former village contributes greatly to the conservation of plant biodiversity. These differences result from their respectively different natural conditions, homegarden areas, homegarden history, homegarden management conditions, traditional knowledge and culture understanding of homegarden manager, local farmers and herdsmen on homegarden plants.The homegarden plants from the three investigated villages are cataloged preliminary in the end of the paper. 相似文献
114.
本文运用量子力学方法对蛋白质分子中孤波传播的非线性动力学特征进行了探讨。研究表明:电离辐射产生的自由基对蛋白质分子的伤害将会对携带能量、信息的孤立子波传播产生较为显著的影响。 相似文献
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Mycotoxin-Producing Strains of Penicillium viridicatum: Classification into Subgroups 总被引:9,自引:4,他引:5 下载免费PDF全文
A. Ciegler D. I. Fennell G. A. Sansing R. W. Detroy G. A. Bennett 《Applied microbiology》1973,26(3):271-278
Fifty-two isolates of Penicillium viridicatum Westling were divided into three groups based on ability to produce ochratoxin and/or citrinin, color, growth rate, type of growth, odor, and isolation source. Members of group I resemble one of the representative strains of P. viridicatum described in the literature; those belonging to group II differ from group I strains in several characteristics; group III is a heterogeneous series of highly variable isolates. Although three subgroupings can be recognized, retention of all isolates in the species P. viridicatum is deemed most appropriate at this time. Spore macerates of all isolates were examined for virus-like particles but none were detected. 相似文献
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Janny C de Grauw Chris HA van de Lest Paul René van Weeren 《Arthritis research & therapy》2009,11(2):R35-8
Introduction
Inflammation is an important feature of many joint diseases, and levels of cartilage biomarkers measured in synovial fluid may be influenced by local inflammatory status. Little is known about the magnitude and time course of inflammation-induced changes in cartilage tissue turnover as measured in vivo by synovial fluid markers. We aimed to study temporal changes in concentrations of inflammatory mediators, matrix metalloproteinase activity and cartilage biomarkers over 1 week in joints with experimentally induced inflammation. 相似文献119.
Nicole A. Renner Hope A. Sansing Fiona M. Inglis Smriti Mehra Deepak Kaushal Andrew A. Lackner Andrew G. MacLean 《Journal of cellular physiology》2013,228(6):1284-1294
The foot processes of astrocytes cover over 60% of the surface of brain microvascular endothelial cells, regulating tight junction integrity. Retraction of astrocyte foot processes has been postulated to be a key mechanism in pathology. Therefore, movement of an astrocyte in response to a proinflammatory cytokine or even limited retraction of processes would result in leaky junctions between endothelial cells. Astrocytes lie at the gateway to the CNS and are instrumental in controlling leukocyte entry. Cultured astrocytes typically have a polygonal morphology until stimulated. We hypothesized that cultured astrocytes which were induced to stellate would have an activated phenotype compared with polygonal cells. We investigated the activation of astrocytes derived from adult macaques to the cytokine TNF‐α under resting and stellated conditions by four parameters: morphology, intermediate filament expression, adhesion, and cytokine secretion. Astrocytes were stellated following transient acidification; resulting in increased expression of GFAP and vimentin. Stellation was accompanied by decreased adhesion that could be recovered with proinflammatory cytokine treatment. Surprisingly, there was decreased secretion of proinflammatory cytokines by stellated astrocytes compared with polygonal cells. These results suggest that astrocytes are capable of multiple phenotypes depending on the stimulus and the order stimuli are applied. J. Cell. Physiol. 228: 1284–1294, 2013. © 2012 Wiley Periodicals, Inc. 相似文献
120.
JANET HIGUTI LUIZ FELIPE MACHADO VELHO FÁBIO AMODÊO LANSAC-TÔHA KOEN MARTENS 《Freshwater Biology》2007,52(10):1930-1943
1. It is widely acknowledged that sudden, large‐scale flood pulses are drivers of benthic and planktonic biodiversity change in floodplains. The impact of such pulses on pleuston (biotic communities associated with root systems of floating plants) remains to be demonstrated. Here, we investigate the effects of local and regional drivers on seasonal changes in abundance and diversity of ostracod communities in pleuston. 2. Temporal and spatial distribution patterns of species richness, abundance, diversity and evenness of ostracods associated with the floating water hyacinth, Eichhornia crassipes, in a lentic environment from the upper Paraná River floodplain, were investigated in relation to local, as well as regional, environmental factors. Ostracods were sampled monthly over an annual cycle (March 2004–February 2005). Twenty‐seven species were found, representing the families Cyprididae, Candonidae, Limnocytheridae and Darwinulidae. Both diversity and abundance of ostracod communities showed seasonal changes, although species turn‐over during the year was limited. 3. We tested two hypotheses concerning the causality of these fluctuations: seasonal recruitment and influx of allochthonous ostracods during the flood pulse. Our results indicate that seasonal recruitment is more likely to be the driver of fluctuations in relation to the flood pulse. We postulate that pleuston communities are buffered against possible detrimental effects of flood pulses. 相似文献