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排序方式: 共有168条查询结果,搜索用时 15 毫秒
21.
Doutrelant C Grégoire A Grnac N Gomez D Lambrechts MM Perret P 《Journal of evolutionary biology》2008,21(1):226-233
It is poorly understood whether female morphological and behavioural traits can be used as 'signals'. In particular, experimental tests of the hypothesis that female ornaments reflect quality are scarce. Here, we experimentally examine whether female plumage coloration might signal maternal quality in the blue tit, Cyanistes caeruleus by forcing half of the females breeding in our population to produce a replacement clutch. Using statistical models that controlled for the effects of male coloration, and the effects of age and condition of both parents, we found that carotenoid-based female coloration was positively linked to key proxies of bird lifetime reproductive success: clutch size, fledgling success and recruitment. Importantly, the relationships between maternal yellow carotenoid coloration and both clutch size and recruitment were stronger in the experimental group than in the control group, indicating that breeding females with higher values of yellow coloration were better able to handle the cost of producing a second clutch. Finally, UV-blue female coloration was positively linked to female survival and marginally linked to laying date. Taken together, these results show for the first time in a natural population that female coloration can indicate individual and maternal quality under natural and adverse reproductive conditions. They highlight the potential for the evolution of female ornamental traits through sexual selection. 相似文献
22.
Erythrocyte Glut1 triggers dehydroascorbic acid uptake in mammals unable to synthesize vitamin C 总被引:1,自引:0,他引:1
Montel-Hagen A Kinet S Manel N Mongellaz C Prohaska R Battini JL Delaunay J Sitbon M Taylor N 《Cell》2008,132(6):1039-1048
23.
Marcel M. Lambrechts Jacques Blondel Sylvie Hurtrez-Bousses Marie Maistre Philippe Perret 《Evolutionary ecology》1997,11(5):599-612
Few studies of natural populations have investigated how phenotypic variation across populations relates to key factors in the environment and landscape structure. In the blue tits of southern France, inter-population differences in reproductive life-history traits (e.g. laying date and clutch size) are small, whatever the timing of maximum caterpillar availability, a key factor for offspring survival in tits. These small differences are attributed to gene flow between local populations occupying different habitat types. In contrast, in blue tits on the island of Corsica, we noted large differences in reproductive life-history traits between two populations, where each population is synchronized with the peak-date of caterpillar abundance. These occur over a short geographical distance (25km). Considering our study within a framework of long-term population studies in tits, our results support the hypothesis that different blue tit populations on Corsica show adaptive differences in life-history traits, and suggest that landscape structure at a small spatial scale can have profound effects on adaptive between-population differentiation in life-history traits that are closely linked with fitness. 相似文献
24.
M. M. Lambrechts P. Perret M. Maistre J. Blondel 《Proceedings. Biological sciences / The Royal Society》1999,266(1426):1311
A complete understanding of the spatio-temporal variation in phenotypic traits in natural populations requires a combination long-term field studies with experiments using captive animals. Field studies allow the formulation of realistic hypotheses, but have the disadvantage that they do not allow the complete control of many potential confounding variables. Studies with captive animals allow tests of hypotheses that cannot be examined in the field, but have the disadvantage that artificial environments may provoke abnormal behaviour. Long-term studies that follow simultaneously captive and wild bird populations are rare. In a study lasting several years, we show here the unexpected patterns that two populations with a similar breeding time in the wild have non-overlapping breeding times in outdoor aviaries, and that two wild populations separated by a short geographical distance show differences in the expression of natural behaviour in captivity. The experimental design used is exceptional in the sense that the captive populations were held at similar latitudes and altitudes as the wild populations. Our case study shows that studies with captive animals can lead to wrong conclusions if they are carried out without population field studies, and without knowledge of the natural habits and habitats of the species involved. To examine the reliability of experiments with captive animals, comparisons with findings from population field studies are essential. 相似文献
25.
Lambrechts A Gevaert K Cossart P Vandekerckhove J Van Troys M 《Trends in cell biology》2008,18(5):220-227
Listeria monocytogenes is a master of mimicry that uses the host cell actin system both to move within the cytoplasm of infected cells and for cell-to-cell spread. Recent studies of Listeria and similarly acting pathogens have generated leaps in our understanding of the actin-based force producing machinery. This machinery is essential for most motile properties of cells, not least for cell migration. In a minimal configuration, it consists of the Arp2/3-complex, Ena-VASP proteins, cofilin, capping protein and a nucleation-promoting factor. In this review, we discuss current models of pseudopodial protrusions and describe how the road to more complex models lies open and is already paved by recent studies using Listeria-based biomimetic motility assays. 相似文献
26.
27.
Louis Lambrechts Christine Chevillon Rebecca G Albright Butsaya Thaisomboonsuk Jason H Richardson Richard G Jarman Thomas W Scott 《BMC evolutionary biology》2009,9(1):160-11
Background
Several observations support the hypothesis that vector-driven selection plays an important role in shaping dengue virus (DENV) genetic diversity. Clustering of DENV genetic diversity at a particular location may reflect underlying genetic structure of vector populations, which combined with specific vector genotype × virus genotype (G × G) interactions may promote adaptation of viral lineages to local mosquito vector genotypes. Although spatial structure of vector polymorphism at neutral genetic loci is well-documented, existence of G × G interactions between mosquito and virus genotypes has not been formally demonstrated in natural populations. Here we measure G × G interactions in a system representative of a natural situation in Thailand by challenging three isofemale families from field-derived Aedes aegypti with three contemporaneous low-passage isolates of DENV-1. 相似文献28.
Sébastien N. Ronkart Michel Paquot Christophe S. Blecker Christian Fougnies Lynn Doran Jean Christophe Lambrechts Bernadette Norberg Claude Deroanne 《Food biophysics》2009,4(1):49-58
The impact of the crystallinity of spray-dried inulins on their stability and physical properties was investigated after a
conditioning of 1 week at different relative humidity levels (0% to 94%) at 20 °C. An environmental scanning electron microscopy
study showed that the amorphous powders hardened at a relative humidity storage between 59% and 75%; while their semi-crystalline
counterparts were partially agglomerated but friable in the same conditions. Caking was observed when the glass transition
temperature of the amorphous phase of the material dropped below the storage temperature of the powder. It resulted in a crystallization
of the structural units of varying lengths composing inulin, but also an increase of the crystallinity of the semi-crystalline
ones. This study showed the importance of the crystallinity of inulin on its stability and physical properties during storage
which is of crucial importance for the shelf-life of food and pharmaceutical products in the dry state.
Financial support was provided for this study by the Walloon Region of Belgium (DGTRE) and Cosucra Groupe Warcoing SA. 相似文献
29.
Anopheles gambiae immune responses to Sephadex beads: involvement of anti-Plasmodium factors in regulating melanization 总被引:3,自引:0,他引:3
Warr E Lambrechts L Koella JC Bourgouin C Dimopoulos G 《Insect biochemistry and molecular biology》2006,36(10):769-778
We have performed a global genome expression analysis of mosquito responses to CM-25 Sephadex beads and identified 27 regulated immune genes, including several anti-Plasmodium factors and other components with likely roles in melanization. Silencing of two bead injection responsive genes, TEP1 and LRIM1, which encode proteins known to mediate Plasmodium killing, significantly compromised the ability to melanize the beads. In contrast, silencing of two Plasmodium protective c-type lectins, CTL4 and CTLMA2, did not affect bead melanization. This data suggest that the anti-Plasmodium factors have dual functions, as determinants of both Plasmodium killing and melanization of the parasite and other foreign bodies, while the Plasmodium protective factors are specifically utilized by the parasite for evasion of mosquito defense mechanisms. 相似文献
30.
Galactodendritic Phthalocyanine Targets Carbohydrate-Binding Proteins Enhancing Photodynamic Therapy
Patrícia M. R. Pereira Sandrina Silva José A. S. Cavaleiro Carlos A. F. Ribeiro Jo?o P. C. Tomé Rosa Fernandes 《PloS one》2014,9(4)
Photosensitizers (PSs) are of crucial importance in the effectiveness of photodynamic therapy (PDT) for cancer. Due to their high reactive oxygen species production and strong absorption in the wavelength range between 650 and 850 nm, where tissue light penetration is rather high, phthalocyanines (Pcs) have been studied as PSs of excellence. In this work, we report the evaluation of a phthalocyanine surrounded by a carbohydrate shell of sixteen galactose units distributed in a dendritic manner (PcGal16) as a new and efficient third generation PSs for PDT against two bladder cancer cell lines, HT-1376 and UM-UC-3. Here, we define the role of galacto-dendritic units in promoting the uptake of a Pc through interaction with GLUT1 and galectin-1. The photoactivation of PcGal16 induces cell death by generating oxidative stress. Although PDT with PcGal16 induces an increase on the activity of antioxidant enzymes immediately after PDT, bladder cancer cells are unable to recover from the PDT-induced damage effects for at least 72 h after treatment. PcGal16 co-localization with galectin-1 and GLUT1 and/or generation of oxidative stress after PcGal16 photoactivation induces changes in the levels of these proteins. Knockdown of galectin-1 and GLUT1, via small interfering RNA (siRNA), in bladder cancer cells decreases intracellular uptake and phototoxicity of PcGal16. The results reported herein show PcGal16 as a promising therapeutic agent for the treatment of bladder cancer, which is the fifth most common type of cancer with the highest rate of recurrence of any cancer. 相似文献