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81.
Y. Saima A. K. Das K. K. Sarkar A. K. SenSr P. Sur 《International journal of biological macromolecules》2000,27(5)
An acidic heteropolysaccharide has been isolated from the tropical angiosperm Feronia limonia syn. F. elephantum (family: Rutaceae). A partially carboxymethylated α-(1–4) polygalacturonan backbone structure with 2- and 2,4-O-α-
-rhamnopyranosyl, 2- and 2,3-O-α-
-arabinofuranosyl and 3-, 2,4-and terminal α-
-galactopyranosyl bearing side chains has been tentatively assigned. The preliminary study in the murine model showed some significant in vivo Ehrlich ascites carcinoma cell growth inhibition. 相似文献
82.
83.
Zafar Rasheed Khaled Zedan Ghada Bin Saif Ragaa H. Salama Tarek Salem Ahmed A. Ahmed Alaa Abd El-Moniem Maha Elkholy Ahmad A. Al Robaee Abdullateef A. Alzolibani 《Clinical and molecular allergy : CMA》2018,16(1):23
Background
Allergic reactions have been implicated as contributions in a number of atopic disorders, including atopic dermatitis (AD), allergic rhinitis (AR) and bronchial asthma (BA). However, the potential for filaggrin protein, eosinophil major basic protein (MBP) and immunoglobulin E (IgE) to elicit allergic response or to contribute to atopic disorders remains largely unexplored in pediatric patients. This study was undertaken to investigate the status and contribution of filaggrin protein, eosinophil MBP and total IgE in pediatric patients with AD, AR and BA.Methods
Sera from 395 pediatric patients of AD, AR or BA with varying levels of disease activity according to the disease activity index and 410 age-matched non-atopic healthy controls were evaluated for serum levels of atopic markers, including filaggrin, eosinophil MBP and IgE.Results
Serum analysis showed that filaggrin levels were remarkably high in pediatric patients with AD, followed by BA and AR, whereas its levels were low in non-atopic pediatric controls. Eosinophil MBP levels in sera of atopic patients were significantly high as compared with their respective controls, but its levels were highest in AR patients, followed by AD and BA. Total IgE in sera of AD patients was markedly high, followed by AR and BA patients, whereas its levels were low in non-atopic pediatric controls. Interestingly, not only was an increased number of subjects positive for filaggrin protein, eosinophil MBP or total IgE, but also their levels were statistically significantly higher among those atopic patients whose disease activity scores were higher as compared with atopic patients with lower disease activity scores.Conclusions
These findings strongly support a role of filaggrin protein, eosinophil MBP and IgE in the onset of allergic reactions in pediatric patients with AD, AR and BA. The data suggest that filaggrin, eosinophil MBP or IgE might be useful in evaluating the progression of AD, AR or BA and in elucidating the mechanisms involved in the pathogenesis of these pediatric disorders.84.
85.
In vitro antibiofilm and anti‐adhesion effects of magnesium oxide nanoparticles against antibiotic resistant bacteria
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Sumreen Hayat Saima Muzammil Muhammad Hidayat Rasool Zonaira Nisar Syed Zajif Hussain Anjum Nasim Sabri Saba Jamil 《Microbiology and immunology》2018,62(4):211-220
86.
Possible protective mechanisms exerted by metformin or metformin and vitamin E in isoproterenol‐induced cardiac injury
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87.
Faiza Gulzar Qaisar Mahmood Zulfiqar Ahmad Bhatti Bibi Saima Zeb Shahida Shaheen Tahir Hayat Naeem Shahid Tahseen Zeb 《World journal of microbiology & biotechnology》2018,34(8):119
Wastewater treatment based on ecological principles is a low cost and highly desirable solution for the developing countries like Pakistan. The present study evaluated the effectiveness of biological treatment systems including Internal Circulation (IC) anaerobic bioreactor and constructed wetlands (CWs) containing macrophytes and mixed algal cultures for industrial wastewater treatment. The IC bioreactor reduced COD (52%), turbidity (89%), EC (24%) of the industrial wastewater. However, the effluents of IC bioreactor did not comply with National Environmental Quality Standards (NEQS) of Pakistan. Post-treatment of IC bioreactor effluents was accomplished in CW containing macrophytes (Arundo donax and Eichhornia crassipes) and mixed algal culture. The CWs planted with macrophytes lowered the concentrations of COD (89%) and turbidity (99%). CWs with algal biomass were not effective in further polishing the effluent. Inhibition of algal biomass growth was observed due to physicochemical characteristics of wastewater. The integrated treatment system consisting of IC bioreactor and macrophytes was found more suitable option for industrial wastewater treatment. 相似文献
88.
Ayesha A. Rasheed Kristina Hambley Gabriel Chan Carlos A. de la Rosa Brenda Larison Daniel T. Blumstein 《Ethology : formerly Zeitschrift fur Tierpsychologie》2018,124(3):155-160
Island populations may provide unique insights into the evolution and persistence of antipredator behavior. If antipredator behavior is costly and islands have reduced predation risk, then we expect the reduction or loss of antipredator behavior on islands. However, if even a single predator remains, the multipredator hypothesis predicts that antipredator behaviors will be conserved. We compared the flight initiation distances (FID) of California quail (Callipepla californica) on Santa Catalina Island (a location with reduced predation pressure) with quail on the mainland. We found no differences in FID between mainland and island quail. However, despite employing consistent testing methods, the starting distance from which quail were approached was significantly reduced for quail studied on the island when compared with quail studied on the mainland. Our results are consistent with the multipredator hypothesis because, while the island population had substantially fewer predators, some predators remained and some antipredator behavior persisted. 相似文献
89.
Pam Fredman Carol J Wikstrand Jan-Eric Månsson Guido Reifenberger Sandy H Bigner Ahmed Rasheed Lars Svennerholm Darell D Bigner 《Glycoconjugate journal》1996,13(3):391-399
The human glioma D-54MG cell line grownin vitro primarily expresses ganglio series gangliosides, particularly GM2. Subcutaneous injection of these cells into nude mice produced xenografts with an increased content of the human glioma-associated lacto series gangliosides, primarily 3-isoLM1, an alteration that was dose dependent, with the highest dose (1×108) resulting in a phenotype that was most like that of the inoculum. After one passagein vivo, the lacto series dominated and reached a proportional level that was kept throughout the 10 passages. The mRNA levels of the GM2-synthase clearly coincided with GM2 expression and was 20 times higher in cells grownin vitro than in those grownin vivo. These results support the view that ganglioside expression in human gliomas is strongly influenced by environmental factors.
Abbreviations: The gangliosides have been designated according to Svennerholm (Eur J Biochem (1977)79: 11–21) GM3, II3NeuAc-LacCer; GM2, II3NeuAc-GgOse3Cer; GM1, II3NeuAc-GgOse4Cer; GD3, II3(NeuAc)2-LacCer; GD2, II3(NeuAc)2-GgOse3Cer; GD1a, IV3NeuAc, II3NeuAc-GgOse4Cer; GD1b, II3(NeuAc)2-GgOse4Cer; GT1b, IV3NeuAc, II3(NeuAc)2-GgOse4Cer; 3-LM1, IV3NeuAc-nLcOse4Cer; 3-isoLM1, IV3NeuAc-LcOse4Cer; 3,6-isoLD1, IV3NeuAc, III6NeuAc-LcOse4Cer; 38-LM1, IV3(NeuAc)2-nLcOse4Cer. MAb(s), monoclonal antibody (ies); the designation LM1 is used when both 3-isoLM1 and 3-LM1 and LD1, when both 36-isoLD1 and 38-LD1 are included. 相似文献
90.
Shafaqat Ali Muhammad Rizwan Najeeb Ullah Saima Aslam Bharwana Muhammad Waseem Muhammad Ahsan Farooq Ghulam Hasan Abbasi Mujahid Farid 《Acta Physiologiae Plantarum》2016,38(11):262
Accumulation of excess copper (Cu) in agricultural soils can decrease growth and quality of crops grown on these soils and a little information is available on the role of silicon (Si) in reducing Cu toxicity in plants. A hydroponic study was conducted to investigate the effects of Si (1.0 mM) on growth and physiology of cotton seedlings grown on different Cu (0, 25, and 50 µM) concentrations. Elevated levels of Cu decreased growth, biomass, photosynthetic pigments, and gas exchange characteristics, and increased the electrolyte leakage (EL), hydrogen peroxide (H2O2), and thiobarbituric acid reactive substances (TBARS) contents in leaf, stem, and roots of cotton seedlings. Cu stress alone decreased the activities of key antioxidant enzymes in cotton seedlings. Exogenous application of Si alleviated the toxic effects of Cu on cotton seedlings by improving growth, photosynthetic pigments, and gas exchange characteristics under Cu stress. The Si application decreased Cu concentrations in leaves, stem, and roots as compared with the control plants. Furthermore, Si decreased oxidative stress as evidenced by decreased EL, H2O2, and TBARS contents, and increased the antioxidant enzyme activities in cotton seedlings. This study provides evidences of Si-mediated reduction of Cu toxicity in cotton seedlings at physiological and biochemical levels. 相似文献