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81.
Siddique Saiful Alom Tamilselvan Thangavel Vishnupriya Manikkannan Balamurugan Elumalai 《Sleep and biological rhythms》2018,16(4):375-385
Sleep and Biological Rhythms - The pressure to stay up longer in our modern society due to constant exposure to artificial light and interactive activities; furthermore, social and economic... 相似文献
82.
AbstractHeavy metals are toxic in nature, and their contamination in foodstuff is a matter of concern for human health. The present study was conducted to assess the concentrations of chromium, nickel, copper, arsenic, cadmium, and lead in rice and vegetables and their possible human health risks in Tangail district, Bangladesh. Metals were measured by inductively coupled plasma mass spectrometry (ICP-MS) after microwave digestion system. The average values of Cr, Ni, Cu, As, Cd, and Pb in rice and vegetables were 16.26, 16.11, 13.99, 2.28, 1.86, and 7.93?mg/kg, respectively. The average metal concentration in rice and vegetable species was in the decreasing order of okra?>?chili?>?bitter gourd?>?papaya?>?brinjal?>?bean?>?bottle gourd?>?rice?>?cucumber?>?sponge gourd?>?Indian spinach. The estimated daily intake (EDI) values of all the metals except Cu were higher than the maximum tolerable daily intake (MTDI). The target hazard quotients (THQs) values of Ni, Cu, As, Cd, and Pb exceeded the threshold value of 1 through consumption of rice and vegetables, indicating significant health risks to both adult and children. The target carcinogenic risk (TR) of As and Pb through consumption of rice and vegetables was higher than the USEPA threshold level (10?4). From the health point of view, this study clearly revealed that consumption of these contaminated rice and vegetables definitely poses carcinogenic and non-carcinogenic risks. 相似文献
83.
Norazua Zakaria Rabiatuladawiyah Ruzmi Salmah Moosa Norhayu Asib Dzarifah Zulperi Siti Izera Ismail Muhammad Saiful Ahmad-Hamdani 《Physiology and Molecular Biology of Plants》2021,27(5):969
Limnocharis flava (L.) Buchenau is a problematic weed in rice fields and water canals of Southeast Asia, and in Malaysia this invasive aquatic weed species has evolved multiple resistance to synthetic auxin herbicide and acetohydroxyacid synthase (AHAS) inhibitors. In this study, it was revealed that, a single nucleotide polymorphism (SNP) at amino acid position 376, where C was substituted to G at the third base of the same codon (GAC to GAG), resulting in Aspartate (Asp) substitution by Glutamate (Glu) was the contributing resistance mechanism in the L. flava population to AHAS inhibitors. In vitro assay further proved that, all the L. flava individuals carrying AHAS resistance mutation exhibited decreased-sensitivity to AHAS inhibitors at the enzyme level. In the bensulfuron-methyl whole-plant bioassay, high resistance indices (RI) of 328- and 437-fold were recorded in the absence and presence of malathion (the P450 inhibitor), respectively. Similarly, translocation and absorption of bensulfuron-methyl in both resistant and susceptible L. flava populations showed no remarkable differences, hence eliminated the possible co-existence of non-target-site resistance mechanism in the resistant L. flava. This study has confirmed another new case of a target-site resistant weed species to AHAS-inhibitors. 相似文献
84.
Mohd Zain Muhammad Zuhair Ismail Nor Hayati Ahmad Nadhirah Sulong Sarina Karsani Saiful Anuar Abdul Majid Nazia 《Molecular biology reports》2020,47(10):7735-7743
Molecular Biology Reports - Telomerase is a cancer promoting ribonucleoprotein complex and is a potential therapeutic target for cancer. In this study, the effects of telomerase downregulation on... 相似文献