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991.
Book reviews in this article:
Buchner, P. , Tiere als Mikrobenzüchter.
Fröhlich, G. , Gallmücken.
Müller, E. W. , Milben an Kulturpflanzen.
Handbuch der Pflanzenphysiologie . Herausgegeben von W. R uhland . 相似文献
Buchner, P. , Tiere als Mikrobenzüchter.
Fröhlich, G. , Gallmücken.
Müller, E. W. , Milben an Kulturpflanzen.
Handbuch der Pflanzenphysiologie . Herausgegeben von W. R uhland . 相似文献
992.
Osmotic adjustment in chickpea (Cicer arietinum L.) results in no yield benefit under terminal drought 总被引:2,自引:0,他引:2
Turner NC Abbo S Berger JD Chaturvedi SK French RJ Ludwig C Mannur DM Singh SJ Yadava HS 《Journal of experimental botany》2007,58(2):187-194
Variation in osmotic adjustment (OA) among chickpea (Cicer arietinumL.) cultivars has been observed when exposed to terminal drought,but some studies suggest that this benefits yield while otherssuggest it does not benefit yield in water-limited environments.In the present study, parents differing in OA were crossed anda set of advanced breeding lines (ABLs) developed for yieldtesting. The variation in OA during podding was measured underterminal drought in the F2, F3, F7, and F8 progeny and in theparents by either rehydrating the leaves before sampling forosmotic potential (OP) or by measuring the relative water content(RWC) and OP on adjacent leaves for the calculation of the OPat full turgor. Yields were measured in the F8 progeny underterminal drought in Australia and India. While differences inOA were measured in the chickpea lines and parents, OA variedfrom year to year and did not consistently benefit yield whenmeasured in the field under terminal drought. In Australia,differences in OA were not associated with any yield benefitin any year, while in India early flowering resulted in higheryields at three of the four sites, and OA had an inconsistenteffect on seed yields. A comparison of OP at full turgor measuredafter rehydration and from measurements of RWC and OP showedthat the rehydration technique underestimated OA. The lack ofcontribution of OA to yield of chickpea is discussed. Key words: Advanced breeding lines, early flowering, phenology, terminal drought, yield components 相似文献
993.
Transcriptional targeting of B cells for induction of peripheral CD8 T cell tolerance 总被引:1,自引:0,他引:1
Werner-Klein M Dresch C Marconi P Brocker T 《Journal of immunology (Baltimore, Md. : 1950)》2007,178(12):7738-7746
994.
Renolleau S Fau S Goyenvalle C Joly LM Chauvier D Jacotot E Mariani J Charriaut-Marlangue C 《Journal of neurochemistry》2007,100(4):1062-1071
Hypoxia-ischaemia in the developing brain results in brain injury with prominent features of apoptosis. In the present study, a third generation dipeptidyl broad-spectrum caspase inhibitor, quinoline-Val-Asp(Ome)-CH2-O-phenoxy (Q-VD-OPh), was tested in a model of unilateral focal ischaemia with reperfusion in 7-day-old rats. Q-VD-OPh (1 mg/kg, i.p.) reduced cell death, resulting in significant neuroprotection at 48 h of recovery (infarct volume of 12.6 +/- 2.8 vs. 24.3 +/- 2.2%, p = 0.006). The neuroprotective effects observed at 48 h post-ischaemia hold up at 21 days of survival time and attenuate neurological dysfunction. Analysis by gender revealed that females were strongly protected (6.7 +/- 3.3%, p = 0.006), in contrast to males in which there was no significant effect, when Q-VD-OPh was given after clip removal on the left common carotid artery. Immunoblot analysis demonstrated that Q-VD-OPh inhibits caspase 3 cleavage into its p17 active form and caspase 1 up-regulation and cleavage in vivo. Following ischaemia in P7 rats, males and females displayed different time course and pattern of cytochrome c release and active p17 caspase 3 during the first 24 h of recovery. In contrast, no significant difference was observed for caspase 1 expression between genders. These results indicate that ischaemia activates caspases shortly after reperfusion and that the sex of the animal may strongly influences apoptotic pathways in the pathogenesis of neonatal brain injury. The specificity, effectiveness, and reduced toxicity of Q-VD-OPh may determine the potential use of peptide-derived irreversible caspase inhibitors as promising therapeutics. 相似文献
995.
The hypothesis that plant species diversity and genetic variation of the host species decrease the severity of plant diseases
is supported by studies of agricultural systems, but experimental evidence from more complex systems is scarce. In an experiment
with grassland communities of varying species richness (1, 2, 4, 8, 16, and 60 species) and functional group richness (1,
2, 3, and 4 functional groups), we used different cultivars of Lolium perenne (perennial ryegrass) to study effects of biodiversity and cultivar identity on the occurrence and severity of foliar fungal
diseases caused by Puccinia coronata (crown rust) and P. graminis (stem rust). Cultivar monocultures of perennial ryegrass revealed strong differences in pathogen susceptibility among these
cultivars. Disease intensity caused by both rust fungi decreased significantly with growing species richness of species mixtures.
The response to the diversity gradient was related to the decreased density and size of the host individuals with increasing
species richness. The occurrence of other grass species known to be possible hosts of the pathogens in the experimental mixtures
did not promote disease intensity in L. perenne, indicating that there was a high host specificity of pathogen strains. Differences in pathogen susceptibility among perennial
ryegrass cultivars persisted independent of diversity treatment, host density and host individual size, but resulted in a
cultivar-specific pattern of changes in pathogen infestation across the species-richness gradient. Our study provided evidence
that within-species variation in pathogen susceptibility and competitive interactions of the host species with the environment,
as caused by species diversity treatments, are key determinants of the occurrence and severity of fungal diseases.
Electronic supplementary material The online version of this article (doi:) contains supplementary material, which is available to authorized users. 相似文献
996.
Developmental genes have pleiotropic effects on plant morphology and source capacity, eventually impacting on seed protein content and productivity in pea
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Burstin J Marget P Huart M Moessner A Mangin B Duchene C Desprez B Munier-Jolain N Duc G 《Plant physiology》2007,144(2):768-781
Increasing pea (Pisum sativum) seed nutritional value and particularly seed protein content, while maintaining yield, is an important challenge for further development of this crop. Seed protein content and yield are complex and unstable traits, integrating all the processes occurring during the plant life cycle. During filling, seeds are the main sink to which assimilates are preferentially allocated at the expense of vegetative organs. Nitrogen seed demand is satisfied partly by nitrogen acquired by the roots, but also by nitrogen remobilized from vegetative organs. In this study, we evaluated the respective roles of nitrogen source capacity and sink strength in the genetic variability of seed protein content and yield. We showed in eight genotypes of diverse origins that both the maximal rate of nitrogen accumulation in the seeds and nitrogen source capacity varied among genotypes. Then, to identify the genetic factors responsible for seed protein content and yield variation, we searched for quantitative trait loci (QTL) for seed traits and for indicators of sink strength and source nitrogen capacity. We detected 261 QTL across five environments for all traits measured. Most QTL for seed and plant traits mapped in clusters, raising the possibility of common underlying processes and candidate genes. In most environments, the genes Le and Afila, which control internode length and the switch between leaflets and tendrils, respectively, determined plant nitrogen status. Depending on the environment, these genes were linked to QTL of seed protein content and yield, suggesting that source-sink adjustments depend on growing conditions. 相似文献
997.
Oxygen, a source of life and stress 总被引:5,自引:0,他引:5
998.
Production of the endocannabinoids anandamide and 2-arachidonoylglycerol by endothelial progenitor cells 总被引:1,自引:0,他引:1
Opitz CA Rimmerman N Zhang Y Mead LE Yoder MC Ingram DA Walker JM Rehman J 《FEBS letters》2007,581(25):4927-4931
Recent studies have highlighted the importance of paracrine growth factors as mediators of pro-angiogenic effects by endothelial progenitor cells (EPCs), but little is known about the release of lipid-based factors like endocannabinoids by EPCs. In the current study, the release of the endocannabinoids anandamide and 2-arachidonoylglycerol by distinct human EPC sub-types was measured using HPLC/tandem mass-spectrometry. Anandamide release was highest by adult blood colony-forming EPCs at baseline and they also demonstrated increased 2-arachidonoylglycerol release with TNF-alpha stimulation. Treatment of mature endothelial cells with endocannabinoids significantly reduced the induction of the pro-inflammatory adhesion molecule CD106 (VCAM-1) by TNF-alpha. 相似文献
999.
1000.
Unraveling tissue regeneration pathways using chemical genetics 总被引:1,自引:0,他引:1
Mathew LK Sengupta S Kawakami A Andreasen EA Löhr CV Loynes CA Renshaw SA Peterson RT Tanguay RL 《The Journal of biological chemistry》2007,282(48):35202-35210
Identifying the molecular pathways that are required for regeneration remains one of the great challenges of regenerative medicine. Although genetic mutations have been useful for identifying some molecular pathways, small molecule probes of regenerative pathways might offer some advantages, including the ability to disrupt pathway function with precise temporal control. However, a vertebrate regeneration model amenable to rapid throughput small molecule screening is not currently available. We report here the development of a zebrafish early life stage fin regeneration model and its use in screening for small molecules that modulate tissue regeneration. By screening 2000 biologically active small molecules, we identified 17 that specifically inhibited regeneration. These compounds include a cluster of glucocorticoids, and we demonstrate that transient activation of the glucocorticoid receptor is sufficient to block regeneration, but only if activation occurs during wound healing/blastema formation. In addition, knockdown of the glucocorticoid receptor restores regenerative capability to nonregenerative, glucocorticoid-exposed zebrafish. To test whether the classical anti-inflammatory action of glucocorticoids is responsible for blocking regeneration, we prevented acute inflammation following amputation by antisense repression of the Pu.1 gene. Although loss of Pu.1 prevents the inflammatory response, regeneration is not affected. Collectively, these results indicate that signaling from exogenous glucocorticoids impairs blastema formation and limits regenerative capacity through an acute inflammation-independent mechanism. These studies also demonstrate the feasibility of exploiting chemical genetics to define the pathways that govern vertebrate regeneration. 相似文献