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Antonio Di Marsico Laura Scrano Rosanna Labella Virginia Lanzotti Roberta Rossi Lucia Cox Michele Perniola Mariana Amato 《Plant and Soil》2018,425(1-2):57-69
Background and aims
Myxodiaspores have been shown to enhance soil-seed contact and improve soil stability. We aim to demonstrate the effect of myxodiaspory on the stability of soil aggregates and gain insight on the nature of bonds.Methods
Mucilage extracted from chia (Salvia hispanica L.) fruits after hydration was mixed with three soils (sandy-loam, loam, clay loam), incubated and tested at different times up to 30 days. We measured aggerate stability by wet sieving and the dynamics of soil CO2 evolution. SEM imaging and 13CPMAS spectroscopy of mucilage were performed in order to infer mechanisms of soil stabilization.Results
The incorporation of mucilage resulted in a dose- and soil-dependent rise in aggregate stability. The dose of 2% mucilage overcame textural effects on soil aggregate stability by providing a 2.3-fold stability increase in the loam and clay-loam and a 4.9-fold increase in the sandy-loam compared to control. The effect persisted after 30 days in spite of C losses due to soil respiration. Mechanisms of soil bonding analogous to xanthan can be inferred from SEM imaging and 13C–CPMAS, since the mucilage was identified as a biopolymer containing 93.39% carbohydrates and 22.02% uronic acids.Conclusions
We demonstrate that mucilage extruded by hydrated diaspores strongly increases soil aggregate stability. This represents a potentially important ecosystem service provided by myxodiasporous crops during germination. Our findings confirm potential applications of mucilage from myxodiaspores as natural soil stabilizers.293.
Rosanna C. Barnard Istvan Z. Kiss Luc Berthouze Joel C. Miller 《Bulletin of mathematical biology》2018,80(10):2698-2733
The duration, type and structure of connections between individuals in real-world populations play a crucial role in how diseases invade and spread. Here, we incorporate the aforementioned heterogeneities into a model by considering a dual-layer static–dynamic multiplex network. The static network layer affords tunable clustering and describes an individual’s permanent community structure. The dynamic network layer describes the transient connections an individual makes with members of the wider population by imposing constant edge rewiring. We follow the edge-based compartmental modelling approach to derive equations describing the evolution of a susceptible–infected–recovered epidemic spreading through this multiplex network of individuals. We derive the basic reproduction number, measuring the expected number of new infectious cases caused by a single infectious individual in an otherwise susceptible population. We validate model equations by showing convergence to pre-existing edge-based compartmental model equations in limiting cases and by comparison with stochastically simulated epidemics. We explore the effects of altering model parameters and multiplex network attributes on resultant epidemic dynamics. We validate the basic reproduction number by plotting its value against associated final epidemic sizes measured from simulation and predicted by model equations for a number of set-ups. Further, we explore the effect of varying individual model parameters on the basic reproduction number. We conclude with a discussion of the significance and interpretation of the model and its relation to existing research literature. We highlight intrinsic limitations and potential extensions of the present model and outline future research considerations, both experimental and theoretical. 相似文献
294.
Rosanna Bissoli Sabrina Battistini Tiziana Guarnieri Antonio Contestabile 《Journal of neurochemistry》1988,50(6):1731-1737
The levels of cholinergic, gamma-aminobutyric acidergic (GABAergic), and excitatory amino acid neurotransmitter markers have been measured in 18 regions of the pigeon telencephalon as well as in supposedly homologous areas of the rat telencephalon. Among the basal telencephalic areas, some similar patterns of regional distribution were observed, with the noticeable exception of the ratio of levels of cholinergic markers between the striatum and globus pallidus, which was much larger in the rat than in the pigeon. In the rat cortical areas, some interesting differences were noticed among the archicortex, the paleocortex, and various parts of the neocortex. In particular, the area identified as prefrontal cortex by previous studies was significantly richer in cholinergic and excitatory amino acid markers and poorer in GABAergic activity than other neocortical regions. In the pigeon, presumedly neocortical equivalent areas--in particular, those constituting the dorsal ventricular ridge--were quite variable in levels of cholinergic markers, and some apparently well-established areas homologous to mammalian neocortex showed exceptionally low levels of cholinergic markers. The higher variability in levels of neurotransmitter-related markers shown by cortically equivalent areas of the avian dorsal ventricular ridge, as compared with the more uniform pattern present in basal telencephalic regions, may be the result of a greater plasticity of these structures during evolution, in response to different selective pressures. 相似文献
295.
Rosanna Ramhorst Esteban Grasso Daniel Paparini Vanesa Hauk Lucila Gallino Guillermina Calo 《Cell Adhesion & Migration》2016,10(1-2):197-207
ABSTRACTChemokine network is central to the innate and adaptive immunity and entails a variety of proteins and membrane receptors that control physiological processes such as wound healing, angiogenesis, embryo growth and development. During early pregnancy, the chemokine network coordinates not only the recruitment of different leukocyte populations to generate the maternal-placental interface, but also constitutes an additional checkpoint for tissue homeostasis maintenance. The normal switch from a pro-inflammatory to an anti-inflammatory predominant microenvironment characteristic of the post-implantation stage requires redundant immune tolerance circuits triggered by key master regulators. In this review we will focus on the recruitment and conditioning of maternal immune cells to the uterus at the early implantation period with special interest on high plasticity macrophages and dendritic cells and their ability to induce regulatory T cells. We will also point to putative immunomodulatory polypeptides involved in immune homeostasis maintenance at the maternal-placental interface. 相似文献
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Noah Fongwen Annelise Wilder-Smith Duane J. Gubler Eng Eong Ooi Edsel Maurice T. Salvana Xavier de Lamballerie Piero L. Olliaro Rosanna W. Peeling 《PLoS neglected tropical diseases》2021,15(7)
With increasing geographic spread, frequency, and magnitude of outbreaks, dengue continues to pose a major public health threat worldwide. Dengvaxia, a dengue live-attenuated tetravalent vaccine, was licensed in 2015, but post hoc analyses of long-term data showed serostatus-dependent vaccine performance with an excess risk of hospitalized and severe dengue in seronegative vaccine recipients. The World Health Organization (WHO) recommended that only persons with evidence of past dengue infection should receive the vaccine. A test for pre-vaccination screening for dengue serostatus is needed. To develop the target product profile (TPP) for a dengue pre-vaccination screening test, face-to-face consultative meetings were organized with follow-up regional consultations. A technical working group was formed to develop consensus on a reference test against which candidate pre-vaccination screening tests could be compared. The group also reviewed current diagnostic landscape and the need to accelerate the evaluation, regulatory approval, and policy development of tests that can identify seropositive individuals and maximize public health impact of vaccination while avoiding the risk of hospitalization in dengue-naive individuals. Pre-vaccination screening strategies will benefit from rapid diagnostic tests (RDTs) that are affordable, sensitive, and specific and can be used at the point of care (POC). The TPP described the minimum and ideal characteristics of a dengue pre-vaccination screening RDT with an emphasis on high specificity. The group also made suggestions for accelerating access to these RDTs through streamlining regulatory approval and policy development. Risk and benefit based on what can be achieved with RDTs meeting minimal and optimal characteristics in the TPP across a range of seroprevalences were defined. The final choice of RDTs in each country will depend on the performance of the RDT, dengue seroprevalence in the target population, tolerance of risk, and cost-effectiveness. 相似文献