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排序方式: 共有589条查询结果,搜索用时 15 毫秒
581.
Biotechnology Letters - The present research work explores the Nattokinase (NK) producing capacity of five Bacillus subtilis strains (MTCC 2616, MTCC 2756, MTCC 2451, MTCC 1427, and MTCC 7164)... 相似文献
582.
583.
Reddy Samyuktha K. Sahu Santosh Kumar Khoja Rohit Kanu Sumit Singh Mandeep 《Plasmonics (Norwell, Mass.)》2022,17(1):257-263
Plasmonics - A complementary metal oxide semiconductor (CMOS) compatible photonic-plasmonic waveguide with nanoscale dimensions and better optical confinement has been proposed for the infrared... 相似文献
584.
Lei Chen Weihuan Cao Rohit Aita Dennis Aldea Juan Flores Nan Gao Edward M. Bonder Christopher E. Ellison Michael P. Verzi 《Cell reports》2021,34(4):108679
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585.
Shanshan Li Jessica De La Cruz Steven Hutchens Somshuvra Mukhopadhyay Zachary K. Criss Rohit Aita Oscar Pellon-Cardenas Joseph Hur Patricia Soteropoulos Seema Husain Puneet Dhawan Lieve Verlinden Geert Carmeliet James C. Fleet Noah F. Shroyer Michael P. Verzi Sylvia Christakos 《Molecular and cellular biology》2021,41(1)
586.
Vitthal Awad Rohit Shirke Sourav Mukherjee Suresh Khadke Pankaj Pawar Nilambika Meti Abhay Harsulkar 《In vitro cellular & developmental biology. Plant》2011,47(4):525-535
Taverniera cuneifolia (Roth) Arn. or Indian licorice is considered to be a substitute for Glycyrrhiza glabra L. owing to an equivalent content of glycyrrhizic acid (GA). GA recognized as the main active ingredient of T. cuneifolia, GA imparts several medicinal properties to these plants. However, research on this plant is scanty with no published record
on tissue culture studies. Present study demonstrates a method for (1) induction and successful development of somatic embryos
from the root culture, (2) regeneration of plants, and (3) GA production by root cultures of T. cuneifolia. Shoot initiation frequency of cultured roots ranged from 52.57% to 97.71%. Plant regeneration frequency (germination) from
somatic embryos was 88.66% in 1/4-strength Murashige and Skoog (MS) medium supplemented with 2% sucrose, as against 68% in
half 1/2-strength MS containing 2% sucrose. Glycyrrhizic acid of 1.32 mg/gm of dry weight was obtained in full-strength MS
medium supplemented with 3% sucrose, through high-performance thin layer chromatography analysis with standard GA in root
cultures. The present study provides an efficient method for the mass production of plants from a single mother plant as well
as the potential root culture system to study the GA production pathways in T. cuneifolia. 相似文献
587.
Rajeev Kapila Renjith Sebastian Vivek Phani Varma D Rohit Sharma Meena Kapasiya Vamshi Salingati Suman Kapila Ajay K. Dang 《Microbiology and immunology》2013,57(11):778-784
The present investigation aimed at identifying the abilities of three different species of probiotic lactobacilli to modulate cellular immune responses in mouse neutrophils and macrophages in vivo over a study period of 60 days. Neutrophil respiratory burst enzymes (cytochrome c reductase and MPO) showed remarkable increased activity (P ≤ 0.01) after consumption of milks fermented by different species of probiotics over 30 and 60 days of feeding trials. Enzyme activities (β‐galactosidase and β‐glucuronidase) and nitric oxide production also increased considerably (P ≤ 0.01) in macrophages, both in peritoneal fluid and in enriched cell cultures. The effects of enhanced enzyme activities were corroborated by simultaneous increases in the phagocytic activities of neutrophils and macrophages. The increases in cellular functions were invariably maximal during the first 30 days of study and were maintained, but did not increase, over the next 30 days. Further, Lactobacillus helveticus‐fed groups were most effective at modulating neutrophil functions whereas Lactobacillus paracasei‐fed groups were more potent at enhancing macrophage functions. Together, our results indicate that probiotics have strain specific effects on stimulating cellular functions while not causing excessive stimulation of the immune system over longer feeding periods, thereby resulting in maximum and stable health benefits. 相似文献
588.
Aaditya Narasimhan Jigisha Rohit Kapila Abhishek Meena Santhosh Nagaraj Guru Prasad 《Journal of evolutionary biology》2023,36(4):730-737
Sexual selection is a major force influencing the evolution of sexually reproducing species. Environmental factors such as larval density can manipulate adult condition and influence the direction and strength of sexual selection. While most studies on the influence of larval crowding on sexual selection are either correlational or single-generation manipulations, it is unclear how evolution under chronic larval crowding affects sexual selection. To answer this, we measured the strength of sexual selection on male and female Drosophila melanogaster that had evolved under chronic larval crowding for over 250 generations in the laboratory, along with their controls which had never experienced crowding, in a common garden high-density environment. We measured selection coefficients on male mating success and sex-specific reproductive success, as separate estimates allowed dissection of sex-specific effects. We show that experimental evolution under chronic larval crowding decreases the strength of sexual and fecundity selection in males but not in females, relative to populations experiencing crowding for the first time. The effect of larval crowding in reducing reproductive success is almost twice in females than in males. Our study highlights the importance of studying how evolution in a novel, stressful environment can shape adult fitness in organisms. 相似文献
589.
Ingvild Aukrust Lise Bj?rkhaug Maria Negahdar Janne Molnes Bente B. Johansson Yvonne Müller Wilhelm Haas Steven P. Gygi Oddmund S?vik Torgeir Flatmark Rohit N. Kulkarni P?l R. Nj?lstad 《The Journal of biological chemistry》2013,288(8):5951-5962
Glucokinase is the predominant hexokinase expressed in hepatocytes and pancreatic β-cells, with a pivotal role in regulating glucose-stimulated insulin secretion, illustrated by glucokinase gene mutations causing monogenic diabetes and congenital hyperinsulinemic hypoglycemia. A complex tissue-specific network of mechanisms regulates this enzyme, and a major unanswered question in glucokinase biology is how post-translational modifications control the function of the enzyme. Here, we show that the pancreatic isoform of human glucokinase is SUMOylated in vitro, using recombinant enzymes, and in insulin-secreting model cells. Three N-terminal lysines unique for the pancreatic isoform (Lys-12/Lys-13 and/or Lys-15) may represent one SUMOylation site, with an additional site (Lys-346) common for the pancreatic and the liver isoform. SUMO-1 and E2 overexpression stabilized preferentially the wild-type human pancreatic enzyme in MIN6 β-cells, and SUMOylation increased the catalytic activity of recombinant human glucokinase in vitro and also of glucokinase in target cells. Small ubiquitin-like modifier conjugation represents a novel form of post-translational modification of the enzyme, and it may have an important regulatory function in pancreatic β-cells. 相似文献