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排序方式: 共有748条查询结果,搜索用时 31 毫秒
721.
Dang Quan Nguyen Dinh Hoa Hoang Michael Nelson Lokesh Nigam Vo Thanh Thao Nguyen Lianjun Zhang Tram Kim Thi Pham Huu Duc Ho Dai Dong Thi Nguyen Trung Quoc Lam Trinh To Tat Yasmin Elhajmoussa Quoc Trung Ly Flavia Pichiorri Vinod Pullarkat Bin Zhang Ya-Huei Kuo Guido Marcucci Le Xuan Truong Nguyen 《Journal of cellular physiology》2020,235(10):7567-7579
722.
Zayneb Hayder Walid Elfalleh Khadija Ben Othman Mohamed Ali Benabderrahim Hédia Hannachi 《农业工程》2021,41(2):150-156
There is a growing request to find an effective method of polyphenols extraction from agro-industry by-product as pomegranate. In this study, response surface methodology (RSM) was used to explore the effect of three factors on ultrasonic assisted extraction (UAE) of total polyphenols (TP), total flavonoids (TF) and condensed tannins (CT) from pomegranate peels. The optimal conditions were determined for each phenolic compound using regression model equations and 3-D plots. The high TP, TF and CT content were obtained with, respectively, liquid/solid ratio of 20.00, 9.77, 9.77, extraction time of 36.38, 41.82, 30.39 min and 36.00, 83.64, 59.26% of ethanol percentage. In fact, liquid/solid ratio of 20, extraction time of 30.94 min and 59.26% of ethanol gives the highest contents of TP, TF and CT simultaneously. The experimental values using optimal conditions agreed with the predicted values. The pomegranate peels extract obtained under optimum conditions have an effective antioxidant activity as determined by ABTS and DPPH assays. 相似文献
723.
724.
ABSTRACT: BACKGROUND: Luteal phase support has been shown by a meta analysis of prospective randomised studies, to be beneficial in establishing a pregnancy after IVF. The optimal length of treatment is unresolved at present and it remains unclear how long to treat women receiving luteal supplementation. It has been used for as little as 2 weeks and for as long as 12 weeks of gestation. OBJECTIVE: To conduct a prospective randomised double blind study to investigate the effect of the duration of luteal support with progesterone in IVF cycles. Trial design: Following 2 weeks of standard treatment and a positive biochemical pregnancy test, this randomised control trial will allocate women to a supplementary 8 weeks of treatment of vaginal progesterone or 8 weeks of placebo. Eligibility: All women presenting to the Hewitt Centre for Reproductive Medicine, Liverpool Women's NHS Foundation Trust, for assisted conception with a positive biochemical pregnancy test at 2 weeks post embryo transfer are eligible to enter the trial. Primary outcome measure:The primary outcome measure is the proportion of all randomised women that continue successfully to a viable pregnancy (at least one fetus with FHR >100 beats minute) on transabdominal / transvaginal ultrasound at 10 weeks post embryo transfer / 12 weeks gestation (i.e. at the end of 8 weeks supplementary trial treatment). 相似文献
725.
Sri Devi Sukumaran Shah Bakhtiar Nasir Jia Ti Tee Michael J. C. Buckle Rozana Othman Noorsaadah Abd. Rahman Vannajan Sanghiran Lee Syed Nasir Abbas Bukhari Chin Fei Chee 《Journal of enzyme inhibition and medicinal chemistry》2021,36(1):130
A series of C4-substituted tertiary nitrogen-bearing 2′-hydroxychalcones were designed and synthesised based on a previous mixed type acetylcholinesterase inhibitor. Majority of the 2′-hydroxychalcone analogues displayed a better inhibition against acetylcholinesterase (AChE) than butyrylcholinesterase (BuChE). Among them, compound 4c was identified as the most potent AChE inhibitor (IC50: 3.3 µM) and showed the highest selectivity for AChE over BuChE (ratio >30:1). Molecular docking studies suggested that compound 4c interacts with both the peripheral anionic site (PAS) and catalytic anionic site (CAS) regions of AChE. ADMET analysis confirmed the therapeutic potential of compound 4c based on its blood–brain barrier penetrating. Overall, the results suggest that this 2′-hydroxychalcone deserves further investigation into the therapeutic lead for Alzheimer’s disease (AD). 相似文献
726.
Mohd A. Hassan Mohammed A. Ahmad Farid Yoshihito Shirai Hidayah Ariffin Mohd R. Othman Mohd H. Samsudin Mohamad Y. Hasan 《Biotechnology journal》2019,14(6)
Oil palm biomass is widely known for its potential as a renewable resource for various value‐added products due to its lignocellulosic content and availability. Oil palm biomass biorefinery is an industry that comes with sociopolitical benefits through job opportunities, as well as potential environmental benefits. Many studies have been conducted on the technological advancements of oil‐palm biomass‐derived renewable materials, which are discussed comprehensively in this review. Recent technological developments have made it possible to bring new and innovative technologies to commercialization, such as compost, biocharcoal, biocomposites, and bioplastics. 相似文献
727.
728.
Sayed K. Goda Yasmin W. Abu Aqel Mai R. Al-Aswad Fatma A. B. Rashedy Amr S. Mohamed 《The protein journal》2010,29(1):44-49
The aim of this study was to evaluate the possibility that synthetic forms of methionine-free alpha-casein and methionine-limited
alpha casein could be produced by recombinant means to form the basis for developing an industrial-scale process for the provision
of a foodstuff suitable for patients with homocystinuria due to cystathionine beta-synthase (CBS) deficiency. As a first step,
two forms of alpha casein gene, encoding methionine-free alpha casein (Fcas) or a methionine-limited alpha casein (Mcas),
were synthesised and expressed in Escherichia coli. Using the overexpression vector pET28a, both genes were highly expressed in E. coli in soluble form as well as in inclusion bodies. The two recombinant proteins were purified by the one step methods using
the fused His-tag and the Ni2+column and validated by Western blot analysis. This work paves the way for industrial-scale production of proteins suitable
for patients with homocystinuria due to CBS deficiency. 相似文献
729.
Ebedy Yasmin A. Hassanen Eman I. Hussien Ahmed M. Ibrahim Marwa A. Elshazly M. O. 《Neurochemical research》2022,47(7):1956-1971
Neurochemical Research - Carbendazim (CBZ) is one of the most common fungicides used to fight plant fungal diseases, otherwise, it leaves residue on fruits, vegetables, and soil that contaminate... 相似文献
730.
Scanning electron microscopy (SEM) of second-stage juveniles (J2), males, and females of Meloidodera floridensis, M. charis, M. belli, and Verutus volvingentis reveals detailed characteristics of the head region, lateral field, phasmid, body striae, vulva, and perineal region. In M. charis and M. belli the en face pattern conforms to a basic pattern in which the labial disc is surrounded by six lips (sectors) of the first head annulation. In J2 the head has additional annulations, whereas in males annulation is replaced by longitudinal blocks. Conversely, J2 and males of M. floridensis and V. volvingentis each have a unique derived face pattern with fusion of various lip components and with head annulation. All six lips of females of M. charis and M. belli are fused, whereas females of M. floridensis and V. volvingentis have distinct lateral lips. Lateral fields vary among species, with only slight differences at the anterior and posterior ends of the lateral lines and in the spatial relation of the lines to phasmid openings. Phasmid openings are present in adults of Meloidodera spp., but were not observed in adults of V. volvingentis; in this respect, the female perineal pattern of Verutus is different from Meloidodera spp, The very large vulva (± 48 μm long) of V. volvingentis is in sharp contrast to the minute vulva (± 6 μm long) in a population of M. charis from San Bernardino. Morphological characters revealed by SEM will be most informative when investigated throughout Heteroderidae and incorporated with additional characters for a phylogenetic analysis of the family. 相似文献