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931.
Inês Carqueijeiro Thomas Dugé de Bernonville Arnaud Lanoue Thu‐Thuy Dang Christiana N Teijaro Christian Paetz Kevin Billet Angela Mosquera Audrey Oudin Sébastien Besseau Nicolas Papon Gaëlle Glévarec Lucía Atehortùa Marc Clastre Nathalie Giglioli‐Guivarc'h Bernd Schneider Benoit St‐Pierre Rodrigo B. Andrade Sarah E. O'Connor Vincent Courdavault 《The Plant journal : for cell and molecular biology》2018,94(3):469-484
932.
Hudson T. Pinheiro Eric Mazzei Rodrigo L. Moura Gilberto M. Amado-Filho Alfredo Carvalho-Filho Adriana C. Braga Paulo A. S. Costa Beatrice P. Ferreira Carlos Eduardo L. Ferreira Sergio R. Floeter Ronaldo B. Francini-Filho Jo?o Luiz Gasparini Raphael M. Macieira Agnaldo S. Martins George Olavo Caio R. Pimentel Luiz A. Rocha Ivan Sazima Thiony Simon Jo?o Batista Teixeira Lucas B. Xavier Jean-Christophe Joyeux 《PloS one》2015,10(3)
Despite a strong increase in research on seamounts and oceanic islands ecology and biogeography, many basic aspects of their biodiversity are still unknown. In the southwestern Atlantic, the Vitória-Trindade Seamount Chain (VTC) extends ca. 1,200 km offshore the Brazilian continental shelf, from the Vitória seamount to the oceanic islands of Trindade and Martin Vaz. For a long time, most of the biological information available regarded its islands. Our study presents and analyzes an extensive database on the VTC fish biodiversity, built on data compiled from literature and recent scientific expeditions that assessed both shallow to mesophotic environments. A total of 273 species were recorded, 211 of which occur on seamounts and 173 at the islands. New records for seamounts or islands include 191 reef fish species and 64 depth range extensions. The structure of fish assemblages was similar between islands and seamounts, not differing in species geographic distribution, trophic composition, or spawning strategies. Main differences were related to endemism, higher at the islands, and to the number of endangered species, higher at the seamounts. Since unregulated fishing activities are common in the region, and mining activities are expected to drastically increase in the near future (carbonates on seamount summits and metals on slopes), this unique biodiversity needs urgent attention and management. 相似文献
933.
Microchemical imaging of iodine distribution in the brown alga Laminaria digitata suggests a new mechanism for its accumulation 总被引:2,自引:0,他引:2
Elodie Françoise Verhaeghe Aurélien Fraysse Jean-Luc Guerquin-Kern Ting-Di Wu Guillaume Devès Charles Mioskowski Catherine Leblanc Richard Ortega Yves Ambroise Philippe Potin 《Journal of biological inorganic chemistry》2008,13(2):257-269
Brown algal kelp species are the most efficient iodine accumulators among all living systems, with an average content of 1.0%
of dry weight in Laminaria digitata. The iodine distributions in stipe and blade sections from L. digitata were investigated at tissue and subcellular levels. The quantitative tissue mapping of iodine and other trace elements (Cl,
K, Ca, Fe, Zn, As and Br) was provided by the proton microprobe with spatial resolutions down to 2 μm. Chemical imaging at
a subcellular resolution (below 100 nm) was performed using the secondary ion mass spectrometry microprobe. Sets of samples
were prepared by both chemical fixation and cryofixation procedures. The latter prevented the diffusion and the leaching of
labile inorganic iodine species, which were estimated at around 95% of the total content by neutron activation analysis. The
distribution of iodine clearly shows a huge, decreasing gradient from the meristoderm to the medulla. The contents of iodine
reach very high levels in the more external cell layers, up to 191 ± 5 mg g−1 of dry weight in stipe sections. The peripheral tissue is consequently the main storage compartment of iodine. At the subcellular
level, iodine is mainly stored in the apoplasm and not in an intracellular compartment as previously proposed. This unexpected
distribution may provide an abundant and accessible source of labile iodine species which can be easily remobilized for potential
chemical defense and antioxidative activities. According to these imaging data, we proposed new hypotheses for the mechanism
of iodine storage in L. digitata tissues.
In memory of Dr. Charles Mioskowski, “Miko,” who died on 2 June 2007. 相似文献
934.
García JJ del Carmen Sáez M De la Fuente M Ortega E 《Molecular and cellular biochemistry》2003,254(1-2):299-304
The regulatory capacity of noradrenaline and its end metabolite 4-hydroxy-3-metoxyphenylglycol (HMPG) on the complete phagocytic process of macrophages were investigated. Either noradrenaline or HMPG did not modify adherence. However, 10–12 M of noradrenaline stimulated the chemotaxis of macrophages, mainly mediated by -adrenergic receptors. In contrast, 10–12 M of HMPG induced an opposed effect on this stage of the phagocytic process. To stimulate phagocytosis, it is necessary to employ a higher concentration (10–5 M) of noradrenaline and this effect was blocked with either 10–6 M propranolol or 10–6 M phentolamine, and maintained by HMPG. Noradrenaline and HMPG did not modify the microbicide capacity of macrophages (measured by O2
– production after phagocytosis). In conclusion, noradrenaline modulates the phagocytic process of macrophages, and this modulation is completed by HMPG, maintaining the phagocytic functions at physiologically optimal levels. Modulation of chemotaxis is mainly mediated by a-receptors and phagocytosis needs both - and -receptor-stimulation. 相似文献
935.
936.
937.
Detection of a novel stem cell probably involved in normal turnover of the lung airway epithelium 下载免费PDF全文
Marta Ortega‐Martínez Laura E. Rodríguez‐Flores Carlos de‐la‐Garza‐González Jesús Ancer‐Rodríguez Gilberto Jaramillo‐Rangel 《Journal of cellular and molecular medicine》2015,19(11):2679-2681
Regeneration of the lung airway epithelium after injury has been extensively studied. In contrast, analysis of its turnover in healthy adulthood has received little attention. In the classical view, this epithelium is maintained in the steady‐state by the infrequent proliferation of basal or Clara cells. The intermediate filament protein nestin was initially identified as a marker for neural stem cells, but its expression has also been detected in other stem cells. Lungs from CD1 mice at the age of 2, 6, 12, 18 or 24 months were fixed in neutral‐buffered formalin and paraffin‐embedded. Nestin expression was examined by an immunohistochemical peroxidase‐based method. Nestin‐positive cells were detected in perivascular areas and in connective tissue that were in close proximity of the airway epithelium. Also, nestin‐positive cells were found among the cells lining the airway epithelium. These findings suggest that nestin‐positive stem cells circulate in the bloodstream, transmigrate through blood vessels and localize in the lung airway epithelium to participate in its turnover. We previously reported the existence of similar cells able to differentiate into lung chondrocytes. Thus, the stem cell reported here might be a bone marrow‐derived mesenchymal stem cell (BMDMSC) able to generate several types of lung tissues. In conclusion, our findings indicate that there exist a BMDMSC in healthy adulthood that participates in the turnover of the lung airway epithelium. These findings may improve our knowledge about the lung stem cell biology and also provide novel approaches to therapy for devastating pulmonary diseases. 相似文献
938.
Ferreira GF Moraes C da Silveira AM Correa-Oliveira R Teixeira-Carvalho A Martins-Filho OA Moreno EC do Carmo LS Fraga LA Malaquias LC 《Memórias do Instituto Oswaldo Cruz》2012,107(3):348-355
We investigated the cytokine profile of peripheral mononuclear cells from chronic osteomyelitis (OST) patients following in vitro stimulation with staphylococcal enterotoxin A (SEA). We demonstrate that stimulation with SEA induced prominent lymphocyte proliferation and high levels of tumour necrosis factor (TNF)-α, interleukin (IL)-4 and IL-10 secretion in both OST and non-infected individuals (NI). Even though stimulation with SEA had no impact on IL-6 production in either patient group, the baseline level of IL-6 production by cells from OST patients was always significantly less than that produced by cells from NI. After classifying the osteomyelitic episodes based on the time after the last reactivation event as "early" (1-4 months) or "late" osteomyelitis (5-12 months), we found that increased levels of TNF-α and IL-4 in combination with decreased levels of IL-6 were observed in the early episodes. By contrast, increased levels of IL-10, IL-2 and IL-6 were hallmarks of late episodes. Our data demonstrate that early osteomyelitic episodes are accompanied by an increased frequency of "high producers" of TNF-α and IL-4, whereas late events are characterised by increased frequencies of "high producers" of IL-10, IL-6 and IL-2. These findings demonstrate the distinct cytokine profiles in chronic osteomyelitis, with a distinct regulation of IL-6 production during early and late episodes. 相似文献
939.
Nunes Bdo N Ramos SB Savegnago RP Ledur MC Nones K Klein CH Munari DP 《Genetics and molecular biology》2011,34(3):429-434
The objective of this study was to estimate genetic and phenotypic correlations of body weight at 6 weeks of age (BW6), as well as final carcass yield, and moisture, protein, fat and ash contents, using data from 3,422 F2 chickens originated from reciprocal cross between a broiler and a layer line. Variance components were estimated by the REML method, using animal models for evaluating random additive genetic and fixed contemporary group (sex, hatch and genetic group) effects. The heritability estimates (h(2)) for BW6, carcass yield and percentage of carcass moisture were 0.31 ± 0.07, 0.20 ± 0.05 and 0.33 ± 0.07, respectively. The h(2) for the percentages of protein, fat and ash on a dry matter basis were 0.48 ± 0.09, 0.55 ± 0.10 and 0.36 ± 0.08, respectively. BW6 had a positive genetic correlation with fat percentage in the carcass, but a negative one with protein and ash contents. Carcass yield, thus, appears to have only low genetic association with carcass composition traits. The genetic correlations observed between traits, measured on a dry matter basis, indicated that selection for carcass protein content may favor higher ash content and a lower percentage of carcass fat. 相似文献
940.