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991.
Guillermo SALGADO‐Maldonado Ma. Isabel Rodriguez‐Vargas Juan José Campos‐Perez 《Studies on Neotropical Fauna and Environment》2013,48(4):245-250
We report for the first time Centrocestus formosanus (Nishigori, 1924) Price, 1932 (Trematoda: Heterophyidae) metacercariae parasitizing natural populations of Xiphophorus hellen (Poeciliidae) and Gobiomorus dormitor (Gobiidae) in Mexico. Adult forms confirming the specific identity were recovered from experimental infections of domestic chicks and laboratory mice. The first intermediate host of this parasite is Melanoides tuberculata, its role in transmission of the infection was assessed by experiments with aquarium Guppies and Cercariae shed from naturally infected snails. Both, the snail and the trematode were introduced in the American continent. 相似文献
992.
Luke J. Sutton David L. Anderson Miguel Franco Christopher J. W. McClure Everton B. P. Miranda F. Hernn Vargas Jos de J. Vargas Gonzlez Robert Puschendorf 《Ecology and evolution》2021,11(1):481-497
Understanding species–environment relationships is key to defining the spatial structure of species distributions and develop effective conservation plans. However, for many species, this baseline information does not exist. With reliable presence data, spatial models that predict geographic ranges and identify environmental processes regulating distribution are a cost‐effective and rapid method to achieve this. Yet these spatial models are lacking for many rare and threatened species, particularly in tropical regions. The harpy eagle (Harpia harpyja) is a Neotropical forest raptor of conservation concern with a continental distribution across lowland tropical forests in Central and South America. Currently, the harpy eagle faces threats from habitat loss and persecution and is categorized as Near‐Threatened by the International Union for the Conservation of Nature (IUCN). Within a point process modeling (PPM) framework, we use presence‐only occurrences with climatic and topographical predictors to estimate current and past distributions and define environmental requirements using Ecological Niche Factor Analysis. The current PPM prediction had high calibration accuracy (Continuous Boyce Index = 0.838) and was robust to null expectations (pROC ratio = 1.407). Three predictors contributed 96% to the PPM prediction, with Climatic Moisture Index the most important (72.1%), followed by minimum temperature of the warmest month (15.6%) and Terrain Roughness Index (8.3%). Assessing distribution in environmental space confirmed the same predictors explaining distribution, along with precipitation in the wettest month. Our reclassified binary model estimated a current range size 11% smaller than the current IUCN range polygon. Paleoclimatic projections combined with the current model predicted stable climatic refugia in the central Amazon, Guyana, eastern Colombia, and Panama. We propose a data‐driven geographic range to complement the current IUCN range estimate and that despite its continental distribution, this tropical forest raptor is highly specialized to specific environmental requirements. 相似文献
993.
994.
Cynthia M. Beall Laura A. Almasy John Blangero Sarah Williams-Blangero Gary M. Brittenham Kingman P. Strohl Michael J. Decker Enrique Vargas Mercedes Villena Rudy Soria Ana Maria Alarcon Cristina Gonzales 《American journal of physical anthropology》1999,108(1):41-51
A range of variation in percent of oxygen saturation of arterial hemoglobin (SaO2) among healthy individuals at a given high altitude indicates differences in physiological hypoxemia despite uniform ambient hypoxic stress. In populations native to the Tibetan plateau, a significant portion of the variance is attributable to additive genetic factors, and there is a major gene influencing SaO2. To determine whether there is genetic variance in other high-altitude populations, we designed a study to test the hypothesis that additive genetic factors contribute to phenotypic variation in SaO2 among Aymara natives of the Andean plateau, a population geographically distant from the Tibetan plateau and with a long, separate history of high-altitude residence. The average SaO2 of 381 Aymara at 3,900–4,000 m was 92 ± 0.15% (SEM) with a range of 84–99%. The average was 2.6% higher than the average SaO2 of a sample of Tibetans at 3,800–4,065 m measured with the same techniques. Quantitative genetic analyses of the Aymara sample detected no significant variance attributable to genetic factors. The presence of genetic variance in SaO2 in the Tibetan sample and its absence in the Aymara sample indicate there is potential for natural selection on this trait in the Tibetan but not the Aymara population. Am J Phys Anthropol 108:41–51, 1999. © 1999 Wiley-Liss, Inc. 相似文献
995.
The actin-based motor protein myosin II regulates MHC class II trafficking and BCR-driven antigen presentation 下载免费PDF全文
Vascotto F Lankar D Faure-André G Vargas P Diaz J Le Roux D Yuseff MI Sibarita JB Boes M Raposo G Mougneau E Glaichenhaus N Bonnerot C Manoury B Lennon-Duménil AM 《The Journal of cell biology》2007,176(7):1007-1019
Antigen (Ag) capture and presentation onto major histocompatibility complex (MHC) class II molecules by B lymphocytes is mediated by their surface Ag receptor (B cell receptor [BCR]). Therefore, the transport of vesicles that carry MHC class II and BCR-Ag complexes must be coordinated for them to converge for processing. In this study, we identify the actin-associated motor protein myosin II as being essential for this process. Myosin II is activated upon BCR engagement and associates with MHC class II-invariant chain complexes. Myosin II inhibition or depletion compromises the convergence and concentration of MHC class II and BCR-Ag complexes into lysosomes devoted to Ag processing. Accordingly, the formation of MHC class II-peptides and subsequent CD4 T cell activation are impaired in cells lacking myosin II activity. Therefore, myosin II emerges as a key motor protein in BCR-driven Ag processing and presentation. 相似文献
996.
Miguel Angel Martínez‐Morales Iriana Zuria Leonardo Chapa‐Vargas Ian MacGregor‐Fors Rubén Ortega‐Álvarez Edgar Romero‐Águila Pilar Carbó 《Diversity & distributions》2010,16(5):786-797
Aim The Rufous‐backed Robin Turdus rufopalliatus is a bird endemic to the Pacific slope of Mexico. The species recently established populations in several localities in the Mexican Central Highlands. Based on available data, we modelled the range expansion of the Rufous‐backed Robin in Mexico to understand the pattern, mechanisms and ecological and biogeographic implications of its expansion. Location Mexico. Methods We assessed the species’ presence and habitat requirements at two spatial scales. At the site level, we evaluated the relationship between land use and species presence in an urban environment. At the country level, we generated a niche model. We then produced a dispersion model through the interpolation of points generated from information derived from the niche model, the location of records within and outside its native distribution range, the species’ natural history, habitat requirements and its estimated dispersion rate (4.2 km year?1). Results The dispersion model predicted that the species will significantly increase its distribution range in Mexico in the coming decades. Its expansion would occur by a stepping‐stone colonization of suitable habitat in areas of native vegetation and human settlements. The model predicted that the species should arrive on the Gulf slope of Mexico before 2025. Main conclusions Mechanisms that could explain the species’ success in establishing viable populations outside its native distribution include its dispersion ability, competitive release, the urban heat island phenomenon and the trade of wild birds. The geographic range expansion of the Rufous‐backed Robin will probably create new interactions with other species, particularly with close taxonomic and ecological relatives. The increase in the distribution range of the Rufous‐backed Robin has resulted from direct and indirect human‐induced dispersion; therefore, it cannot be considered a fading endemism. In part of its expanded range (to date the Mexican Central Highlands), it should be considered an invasive alien species. 相似文献
997.
Phenylketonuria (PKU) is an inborn error of amino acid metabolism caused by severe deficiency of phenylalanine hydroxylase
activity, leading to the accumulation of phenylalanine and its metabolites in blood and tissues of affected patients. Phenylketonuric
patients present as the major clinical feature mental retardation, whose pathomechanisms are poorly understood. In recent
years, mounting evidence has emerged indicating that oxidative stress is possibly involved in the pathology of PKU. This article
addresses some of the recent developments obtained from animal studies and from phenylketonuric patients indicating that oxidative
stress may represent an important element in the pathophysiology of PKU. Several studies have shown that enzymatic and non-enzymatic
antioxidant defenses are decreased in plasma and erythrocytes of PKU patients, which may be due to an increased free radical
generation or secondary to the deprivation of micronutrients which are essential for these defenses. Indeed, markers of lipid,
protein, and DNA oxidative damage have been reported in PKU patients, implying that reactive species production is increased
in this disorder. A considerable set of data from in vitro and in vivo animal studies have shown that phenylalanine and/or
its metabolites elicit reactive species in brain rodent. These findings point to a disruption of pro-oxidant/antioxidant balance
in PKU. Considering that the brain is particularly vulnerable to oxidative attack, it is presumed that the administration
of appropriate antioxidants as adjuvant agents, in addition to the usual treatment based on restricted diets or supplementation
of tetrahydrobiopterin, may represent another step in the prevention of the neurological damage in PKU. 相似文献
998.
Travis EK Vargas FH Merkel J Gottdenker N Miller RE Parker PG 《Journal of wildlife diseases》2006,42(1):133-141
The flightless cormorant (Phalacrocorax harrisi) is an endemic species of the Galápagos Islands, Ecuador. Health studies of the species have not previously been conducted. In August 2003, baseline samples were collected from flightless cormorant colonies on the islands of Isabela and Fernandina. Seventy-six birds, from nestlings to adults, were evaluated. Genetic sexing of 70 cormorants revealed 37 females and 33 males. Hematology assessment consisted of packed cell volume (n=19), leukograms (n=69), and blood smear evaluation (n=69). Microscopic evaluation of blood smears revealed microfilaria in 33% (23/69) of the cormorants. Plasma chemistries were performed on 46 cormorants. There was no significant difference in chemistry values or complete blood counts between male and female cormorants or between age groups. Based on a serologic survey to assess exposure to avian pathogens, birds (n=69) were seronegative for West Nile virus, avian paramyxovirus type 1 (Newcastle disease virus), avian paramyxovirus types 2 and 3, avian influenza, infectious bursal disease, infectious bronchitis, Marek's disease (herpes), reovirus, avian encephalomyelitis, and avian adenovirus type 2. Antibodies to avian adenovirus type 1 and Chlamydophila psittaci were found in 31% (21/68) and 11% (7/65) of flightless cormorants respectively. Chlamydophila psittaci was detected via polymerase chain reaction in 6% (2/33) of the cormorants. The overall negative serologic findings of this research suggest that the flightless cormorant is an immunologically na?ve species, which may have a reduced capacity to cope with the introduction of novel pathogens. 相似文献
999.
Fernanda da S. Moreira Pedro B. da Costa Rocheli de Souza Anelise Beneduzi Bruno B. Lisboa Luciano K. Vargas Luciane M. P. Passaglia 《Genetics and molecular biology》2016,39(1):111-121
In the pursuit of sustainable agriculture, bioinoculants usage as providers of a
crop''s needs is a method to limit environmental damage. In this study, a
collection of cultivable putative plant growth promoting (PGP) bacteria
associated with wheat crops was obtained and this bacterial sample was
characterized in relation to the functional diversity of certain PGP features.
The isolates were obtained through classical cultivation methods, identified by
partial 16S rRNA gene sequencing and characterized for PGP traits of interest.
Functional diversity characterization was performed using Categorical Principal
Component Analysis (CatPCA) and Multiple Correspondence Analysis (MCA). The most
abundant genera found among the 346 isolates were Pseudomonas,
Burkholderia, and Enterobacter. Occurrence of PGP
traits was affected by genus, niche, and sampling site. A large number of genera
grouped together with the ability to produce indolic compounds; phosphate
solubilization and siderophores production formed a second group related to
fewer genera, in which the genus Burkholderia has a great
importance. The results obtained may help future studies aiming prospection of
putative plant growth promoting bacteria regarding the desired organism and PGP
trait. 相似文献
1000.
Vargas SM Araújo FC Monteiro DS Estima SC Almeida AP Soares LS Santos FR 《The Journal of heredity》2008,99(2):215-220
The leatherback sea turtle (Dermochelys coriacea) population that nests in Brazil is restricted to a few individuals, but high densities of pelagic individuals are observed along the southern and southeastern Brazilian coast. We investigated the diversity of the mitochondrial DNA (mtDNA) control region in order to understand the relationship between nesting and pelagic leatherbacks from Brazil and elsewhere. High-quality 711-bp sequences were generated, analyzed, and compared with published data from worldwide populations. We detected the presence of shared haplotypes between nesting and pelagic aggregates from Brazil, as well as haplotypes shared with other nesting areas from the Atlantic and Pacific. Furthermore, the use of longer control region sequences allowed the subdivision of the common Atlantic haplotype A into 3 different haplotypes (A1, A3, and A4), thus improving the resolution of mtDNA-based leatherback phylogeography. The use of longer sequences partially supported a closer association between nesting and pelagic individuals from Brazil and pointed to a complex origin for the pelagic individuals in the Brazilian coast. 相似文献