Male sex chromosomal complement exacerbates the pathogenicity of Th17 cells in a chronic model of central nervous system autoimmunity

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Influence of selected sugars and temperature on fatty acids composition in Candida lipolytica

Summary An investigation was made of the effects of temperature and of mono- and disaccharides on lipids, biomass, odd-chain and unsaturated fatty acids production of Candida lipolytica. With different sugars as carbon source at 30°C, the order for biomass production was: fructose > glucose > sucrose > lactose > galactose, while lipids production/g biomass decreased as follows: lactose, sucrose, galactose, fructose and glucose. On the other hand, the odd-chain fatty acids contents decreased in the following order: fructose, lactose, glucose, sucrose and galactose. Lowering the temperature of cultivation to 15°C, biomass, lipids and unsaturated fatty acids decreased. However, a notable decrease in the content of odd-chain fatty acids was detected.     

Characterization of magnesium and calcium tenuazonate from Phoma sorghina

Phoma sorghina Sacc., the fungus implicated in the aetiology of onyalai, a haematologic disorder, produces magnesium and calcium tenuazonate as toxic constituents.     

Potent SARS-CoV-2 neutralizing antibodies directed against spike N-terminal domain target a single supersite

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A new diet for reproduction of two predaceous mitesAmblyseius gossipi andAgistemus exsertus [Acari: Phytoseiidae,stigmaeidae]

Laboratory studies revealed that the acarid mite,Tyrophagus casei Oudemans is an adequate diet for development and reproduction of the stigmaeid mite,Agistemus exsertus Gonzalez. A combination of pollen grains of castor beanRicinus communis L. andT. casei is a sufficient plant-animal diet for the development and reproduction of the phytoseiid mite,Amblyseius gossipi Elbadry. When the later predator was restricted to such animal prey it developed to the adult stage, but females failed to lay eggs.      

Amylin,Food Intake,and Obesity

Amylin, also known as islet amyloid polypeptide, identified in 1987, is a naturally occurring hormone, released by the β cells of the pancreas and consists of 37 amino acids. Amylin seems to decrease food intake through both central and peripheral mechanisms and indirectly by slowing gastric emptying. The mean basal amylin concentration is higher in obese than in lean human subjects. The amylin response to oral glucose is also greater in obese subjects, whether or not they have impaired glucose tolerance. The elevated amylin levels in obesity may lead to down-regulation of amylin receptors and lessen the impact of postprandial amylin secretion on satiety and gastric emptying. Amylin administration may overcome resistance at target tissues, delay gastric emptying, and have potential for inducing weight loss in obese individuals.