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饰纹姬蛙的早期胚胎发育 总被引:6,自引:3,他引:6
本文报道了饰纹姬蛙的早期胚胎发育。自受精卵期到出水孔完善期共分25个时期,其发育进程及各时期胚胎的外形特征与四川狭口蛙基本相似,但其胚胎孵化的迟早差距较大。在水温21±0.5℃和24±0.5℃条件下,其胚胎发育的全过程历时分别为76h56min和61h52min。 相似文献
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Ran Xiao Shan Li Qian Cao Xiuling Wang Qiujin Yan Xiaoning Tu Ying Zhu Fan Zhu 《中国病毒学》2017,32(3):216-225
Human endogenous retrovirus W env(HERV-W env) plays a critical role in many neuropsychological diseases such as schizophrenia and multiple sclerosis(MS). These diseases are accompanied by immunological reactions in the central nervous system(CNS). Microglia are important immunocytes in brain inflammation that can produce a gasotransmitter – nitric oxide(NO). NO not only plays a role in the function of neuronal cells but also participates in the pathogenesis of various neuropsychological diseases. In this study, we reported increased NO production in CHME-5 microglia cells after they were transfected with HERV-W env. Moreover, HERV-W env increased the expression and function of human inducible nitric oxide synthase(hi NOS) and enhanced the promoter activity of hi NOS. Microglial migration was also enhanced. These data revealed that HERV-W env might contribute to increase NO production and microglial migration ability in neuropsychological disorders by regulating the expression of inducible NOS. Results from this study might lead to the identification of novel targets for the treatment of neuropsychological diseases, including neuroinflammatory diseases, stroke, and neurodegenerative diseases. 相似文献
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