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161.
Bing‐Qing Xiong Xinwei Zhou Gui‐Liang Xu Yuzi Liu Likun Zhu Youcheng Hu Shou‐Yu Shen Yu‐Hao Hong Si‐Cheng Wan Xiao‐Chen Liu Xiang Liu Shengli Chen Ling Huang Shi‐Gang Sun Khalil Amine Fu‐Sheng Ke 《Liver Transplantation》2020,10(4)
Alloy materials such as Si and Ge are attractive as high‐capacity anodes for rechargeable batteries, but such anodes undergo severe capacity degradation during discharge–charge processes. Compared to the over‐emphasized efforts on the electrode structure design to mitigate the volume changes, understanding and engineering of the solid‐electrolyte interphase (SEI) are significantly lacking. This work demonstrates that modifying the surface of alloy‐based anode materials by building an ultraconformal layer of Sb can significantly enhance their structural and interfacial stability during cycling. Combined experimental and theoretical studies consistently reveal that the ultraconformal Sb layer is dynamically converted to Li3Sb during cycling, which can selectively adsorb and catalytically decompose electrolyte additives to form a robust, thin, and dense LiF‐dominated SEI, and simultaneously restrain the decomposition of electrolyte solvents. Hence, the Sb‐coated porous Ge electrode delivers much higher initial Coulombic efficiency of 85% and higher reversible capacity of 1046 mAh g?1 after 200 cycles at 500 mA g?1, compared to only 72% and 170 mAh g?1 for bare porous Ge. The present finding has indicated that tailoring surface structures of electrode materials is an appealing approach to construct a robust SEI and achieve long‐term cycling stability for alloy‐based anode materials. 相似文献
162.
163.
Shen He Wu Shuyu Chen Xi Xu Bai Ma Dezun Zhao Yannan Zhuang Yan Chen Bing Hou Xianglin Li Jiayin Cao Yudong Fu Xianyong Tan Jun Yin Wen Li Juan Meng Li Shi Ya Xiao Zhifeng Jiang Xingjun Dai Jianwu 《中国科学:生命科学英文版》2020,63(12):1879-1886
Science China Life Sciences - Spinal cord injury (SCI), especially complete transected SCI, leads to loss of cells and extracellular matrix and functional impairments. In a previous study, we... 相似文献
164.
165.
Dingqian Wu Xiaoxiao Fu Yuanyuan Zhang Qiang Li Ligang Ye Shu Han Mao Zhang 《Experimental biology and medicine (Maywood, N.J.)》2020,245(18):1683
C16 peptide and angiopoietin-1 (Ang-1) have been found to have anti-inflammatory activity in various inflammation-related diseases. However, their combined role in acute respiratory distress syndrome (ARDS) has not been investigated yet. The objective of this study was to investigate the effects of C16 peptide and Ang-1 in combination with lipopolysaccharide (LPS)-induced inflammatory insult in vitro and in vivo. Human pulmonary microvascular endothelial cells and human pulmonary alveolar epithelial cells were used as cell culture systems, and an ARDS rodent model was used for in vivo studies. Our results demonstrated that C16 and Ang-1 in combination significantly suppressed inflammatory cell transmigration by 33% in comparison with the vehicle alone, and decreased the lung tissue wet-to-dry lung weight ratio to a maximum of 1.53, compared to 3.55 in the vehicle group in ARDS rats. Moreover, C + A treatment reduced the histology injury score to 60% of the vehicle control, enhanced arterial oxygen saturation (SO2), decreased arterial carbon dioxide partial pressure (PCO2), and increased oxygen partial pressure (PO2) in ARDS rats, while also improving the survival rate from 47% (7/15) to 80% (12/15) and diminishing fibrosis, necrosis, and apoptosis in lung tissue. Furthermore, when C + A therapy was administered 4 h following LPS injection, the treatment showed significant alleviating effects on pulmonary inflammatory cell infiltration 24 h postinsult. In conclusion, our in vitro and in vivo studies show that C16 and Ang-1 exert protective effects against LPS-induced inflammatory insult. C16 and Ang-1 hold promise as a novel agent against LPS-induced ARDS. Further studies are needed to determine the potential for C16 and Ang-1 in combination in treating inflammatory lung diseases. 相似文献
166.
Jin‐Ling Fu Qiong Yu Meng‐Di Li Chun‐Mei Hu Guang Shi 《Journal of biochemical and molecular toxicology》2020,34(5)
Heart failure (HF) is a medical condition inability of the heart to pump sufficient blood to meet the metabolic demand of the body to take place. The number of hospitalized patients with cardiovascular diseases is estimated to be more than 1 million each year, of which 80% to 90% of patients ultimately progress to decompensated HF. Digitalis glycosides exert modest inotropic actions when administered to patients with decompensated HF. Although its efficacy in patients with HF and atrial fibrillation is clear, its value in patients with HF and sinus rhythm has often been questioned. A series of recent studies have cast serious doubt on the benefit of digoxin when added to contemporary HF treatment. We are hypothesizing the role and mechanism of exosome and its biological constituents responsible for worsening the disease state and mortality in decompensated HF patients on digitalis. 相似文献
167.
168.
Wang Haili Xu Yuanyuan Xu Aiqing Wang Xinghua Cheng Lijun Lee Sharen Tse Gary Li Guangping Liu Tong Fu Huaying 《Journal of physiology and biochemistry》2020,76(4):637-653
Journal of Physiology and Biochemistry - Atrial remodeling in diabetes is partially attributed to NF-κB/TGF-β signal transduction pathway activation. We examined whether the... 相似文献
169.
Du Xuemei Fang Ting Liu Yan Huang Liying Wang Xiaoli Zhang Jie Cui Yangbo Zang Maosen Wang Guoying Fu Junjie Liu Yunjun 《In vitro cellular & developmental biology. Plant》2020,56(2):159-168
In Vitro Cellular & Developmental Biology - Plant - Callus induction in plants is similar to pluripotent stem cell induction in animals and can incite global changes in gene expression.... 相似文献
170.
Xiao‐Li Li Fei Yu Bao‐Ying Li Chun‐Li Fu Xin Yu Mei Xu Mei Cheng Hai‐Qing Gao 《Cell biology international》2020,44(1):268-277
The progression of diabetic cardiomyopathy is related to cardiomyocyte dysfunction and apoptosis. Our previous studies showed that asporin (ASPN) was significantly increased in the myocardium of db/db mice through proteomics, and grape seed procyanidin B2 (GSPB2) significantly inhibited the expression of ASPN in the heart of db/db mice. We report here that ASPN played a critical role in glycated low‐density lipoproteins (gly‐LDL) induced‐cardiomyocyte apoptosis. We found that gly‐LDL upregulated ASPN expression. ASPN increased H9C2 cardiomyocyte apoptosis with down‐regulation of Bcl‐2, upregulation of transforming growth factor‐β1, Bax, collagen III, fibronectin, and phosphorylation of smad2 and smad3. However, GSPB2 treatment reversed ASPN‐induced impairments in H9C2 cardiomyocytes. These results provide evidence for the cardioprotective action of GSPB2 against ASPN injury, and thus suggest a new target for fighting against diabetic cardiomyopathy. 相似文献