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191.
192.
Donato Torre Agostino Pugliese Carlo Quadrelli Carmen Sampietro Stefania Rossi 《FEMS microbiology letters》1989,57(2):209-212
The total number of lymphocytes in the bronchoalveolar lavage (BAL) fluids significantly increased in mice injected intravenously with pertussis toxin (PT), while the absolute number of alveolar macrophages markedly decreased. This finding probably reflects the lymphocyte accumulation in interstitial spaces as we previously observed in mice injected with PT. In addition, indomethacin, at lower dosage (0.5 mg/kg) prevented peripheral lymphocytosis and lymphocyte accumulation in the alveolar spaces of the lungs of mice injected with PT. These results provide evidence that PT is responsible for lymphocyte accumulation together with a marked decrease of alveolar macrophages in the lungs of treated mice; moreover, indomethacin is effective in preventing bronchoalveolar changes caused by PT. 相似文献
193.
M. Pugliese V. Bengin M. Casolino V. Roca A. Zanini M. Durante 《Radiation and environmental biophysics》2010,49(3):359-363
Radiation assessment and protection in space is the first step in planning future missions to the Moon and Mars, where mission
and number of space travelers will increase and the protection of the geomagnetic shielding against the cosmic radiation will
be absent. In this framework, the shielding effectiveness of two flexible materials, Kevlar and Nextel, were tested, which
are largely used in the construction of spacecrafts. Accelerator-based tests clearly demonstrated that Kevlar is an excellent
shield for heavy ions, close to polyethylene, whereas Nextel shows poor shielding characteristics. Measurements on flight
performed onboard of the International Space Station and of the Foton-M3 capsule have been carried out with special attention
to the neutron component; shielded and unshielded detectors (thermoluminescence dosemeters, bubble detectors) were exposed
to a real radiation environment to test the shielding properties of the materials under study. The results indicate no significant
effects of shielding, suggesting that thin shields in low-Earth Orbit have little effect on absorbed dose. 相似文献
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