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911.
912.
REGIONAL AND SUBCELLULAR DISTRIBUTION OF PROTEIN CARBOXYMETHYLASE IN BRAIN AND OTHER TISSUES 总被引:3,自引:0,他引:3
Protein carboxymethylase, an enzyme that transfcrs the methyl group of S-adenosyl-L-methionine to carboxyl groups of proteins and endogenous acceptor proteins were examined in nerve and endocrine tissues. The highest protein carboxymethylase activity was found in the brain, followed by the testis, pituitary and heart. On the other hand, the tissue with the highest level of endogenous substrate(s) was the pituitary. The nearly identical specific activity ratio for two different protein substrates in all tissues examined, suggests that one enzyme is responsible for carboxymethylase activity in different tissues. The subcellular distribution of the enzyme in brain showed a high concentration in the soluble fraction, presumably representative of the enzyme in the cytosol of cell bodies. Considerable enzyme activity was also found in brain synaptosomes which was increased by osmotic lysis. Protein carboxymethylase was shown to accumulate proximally to a ligation of the rat sciatic nerve. A possible physiological role for protein carboxymethylase in neuronal function is discussed. 相似文献
913.
SYNOPSIS. Profound developmental changes occur in the morphologyand physiology of the respiratory system of amphibians duringthe transition from strictly aquatic to dual aquatic-aerialbreathing. This developmental transition usually involves modificationsin ventilatory mechanisms and/or respiratory surfaces {e.g.,degeneration of gills, ventilation of functional lungs). Boththe first appearance of obligate air breathing and the subsequentdependence upon it by amphibian larvae are sensitive to a varietyof environmental stressors during critical developmental periods.These stressors include oxygen availability, ambient temperature,the risk of predation and mode of feeding. 相似文献
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917.
A A Paszek LB Schook C F Louis JR Mickelson G H Flickinger J Murtaugh J R Mendiola M A Janzen C W Beattie G A Rohrer L J Alexander L Andersson H Ellegren M Johansson P Mariani L Marklund B Høyheim W Davies M Fredholm A L Archibald C S Haley 《Animal genetics》1995,26(6):377-386
Recent advances in the use of microsatellite markers and the development of comparative gene mapping techniques have made the construction of high resolution genetic maps of livestock species possible. Framework and comprehensive genetic linkage maps of porcine chromosome 6 have resulted from the first international effort to integrate genetic maps from multiple laboratories. Eleven highly polymorphic genetic markers were exchanged and mapped by four independent laboratories on a total of 583 animals derived from four reference populations. The chromosome 6 framework map consists of 10 markers ordered with high local support. The average marker interval of the framework map is 15.1 cM (sex averaged). The framework map is 135, 175 and 109 cM in length (for sex averaged, female and male maps, respectively). The comprehensive map includes a total of 48 type I and type II markers with a sex averaged interval of 3.5 cM and is 166, 196 and 126 cM (for sex averaged, female and male maps, respectively). Additional markers within framework map marker intervals can thus be selected from the comprehensive map for further analysis of quantitive trait loci (QTL) located on chromosome 6. The resulting maps of swine chromosome 6 provide a valuable tool for analysing and locating QTL. 相似文献
918.
SYNOPSIS. The fine structure of the eugregarine Lankesteria culicis from the larvae of the mosquito Aedes aegypti was examined by light and electron microscopy and compared with that of other gregarines. The cell organelles found in L. culicis included a nucleus, mitochondria, Golgi-complexes, endoplasmic reticulum, vesicles, droplets, granules and lipid bodies.
The surface of L. culicis was composed of a highly differentiated membrane-cortex, differing slightly from that of other eugregarines. This complex was limited by a unit membrane, the plasmelemma, and underlying cortical laminae which appeared to be composed of several layers. The homogeneous electrondense layer present in Pyxinoides balani was greatly diminished or absent in L. culicis.
A series of laminar folds supported by ground substance and longitudinal subpellicular fibrils gave the organism's surface a ridge-like appearance. Permanent cytostome-like openings in the surface, which appeared to be supported by a narrow band of thickened cortex, were present as specializations of the surfacemembrane complex. The structural composition of the parasite appeared quite striking in that it was made up almost entirely of vesicles, granules, and droplets which were absent only in the area of the protomerite. The mitochondria were usually found just beneath the surface or near the nucleus. Mitochondria were also seen in the region of demarcation between the protomerite and deutomerite. 相似文献
The surface of L. culicis was composed of a highly differentiated membrane-cortex, differing slightly from that of other eugregarines. This complex was limited by a unit membrane, the plasmelemma, and underlying cortical laminae which appeared to be composed of several layers. The homogeneous electrondense layer present in Pyxinoides balani was greatly diminished or absent in L. culicis.
A series of laminar folds supported by ground substance and longitudinal subpellicular fibrils gave the organism's surface a ridge-like appearance. Permanent cytostome-like openings in the surface, which appeared to be supported by a narrow band of thickened cortex, were present as specializations of the surfacemembrane complex. The structural composition of the parasite appeared quite striking in that it was made up almost entirely of vesicles, granules, and droplets which were absent only in the area of the protomerite. The mitochondria were usually found just beneath the surface or near the nucleus. Mitochondria were also seen in the region of demarcation between the protomerite and deutomerite. 相似文献
919.
Reproductive Effects of the Mammalian Pineal 总被引:1,自引:0,他引:1
The reproductive systems of mammals are anatomically and physiologicallyaltered by the pineal gland. Characteristically, pineal removalaccelerates gonadal growth in immature animals and causes atransient modest enlargement of the reproductive organs if theoperations are done after adulthood is attained. Light deprivationrenders the pineal strongly antigonadotropic. In addition, thereare several conditions, e.g., androgen-sterilization and anosmia,which potentiate, probably indirectly, the gonad-inhibitingcapability of the rat's pineal. The chronic administration ofpineal extracts or pineal substances has effects opposite topinealectomy, i.e., they restrict gonadal development or growth.The pineal is possibly important in adjusting the level of reproductiveactivity to seasonal changes in environmental conditions. 相似文献
920.