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111.
Yeung M Balma-Mena A Shear N Simor A Pope E Walsh S McGavin MJ 《Microbes and infection / Institut Pasteur》2011,13(2):189-197
Staphylococcus aureus promotes the onset and severity of atopic dermatitis (AD), which is exacerbated by superantigen toxins SEB and SEC. The genetic identity of these isolates, and their relationship to common hospital- or community-associated methicillin resistant S. aureus (HA-MRSA and CA-MRSA) has not been defined. We conducted spa typing, partial multi-locus sequence typing (MLST), and toxin profiling (seb, sec, lukS-PV) of S. aureus from 119 pediatric and 40 adult AD patients. MLST clonal complexes CC45, CC5, CC15, CC1, CC8 and CC30 accounted for 79% of isolates, representing the same major groups reported for nosocomial S. aureus in hospital intensive care units. The highest disease severity was associated with CC1, which was significantly greater relative to CC15 (p?=?0.017) or CC30 (p?=?0.040), but with no significant difference relative to CC45, CC5 or CC8. Although there were two few lukS-PV, seb or sec isolates to infer a role in disease severity, CC45 was identified as a source of SEC producing strains, and lukS-PVL was associated with a small number of CC5 pediatric isolates. CC1 harbored the only CA-MRSA that was identified, and was a source of isolates that expressed both seb and sec, and closely resembled the USA400 strain of CA-MRSA. 相似文献
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William J. Pope 《BMJ (Clinical research ed.)》1923,1(3254):833-834
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F. M. Pope 《BMJ (Clinical research ed.)》1907,1(2425):1471-1477
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Howard C. Stutz C. Lorenzo Pope Stewart C. Sanderson 《American journal of botany》1979,66(10):1181-1193
Much of the variation in hexaploid Atriplex tridentata appears to have come from tetraploid A. canescens by introgression. Among the recombinations, three types appear to have become established as new, adaptive, hexaploid derivatives. One of these is a robust, woody form near Knolls, Utah, another is a widespread, low-growing, shrubby form in Lander County, Nevada, the other is an upright bushy, canescens-like form near Grantsville, Utah. 相似文献
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