全文获取类型
收费全文 | 719篇 |
免费 | 63篇 |
出版年
2022年 | 4篇 |
2021年 | 5篇 |
2020年 | 8篇 |
2019年 | 7篇 |
2018年 | 18篇 |
2017年 | 7篇 |
2016年 | 13篇 |
2015年 | 30篇 |
2014年 | 32篇 |
2013年 | 32篇 |
2012年 | 48篇 |
2011年 | 48篇 |
2010年 | 34篇 |
2009年 | 33篇 |
2008年 | 36篇 |
2007年 | 34篇 |
2006年 | 36篇 |
2005年 | 26篇 |
2004年 | 40篇 |
2003年 | 45篇 |
2002年 | 28篇 |
2001年 | 15篇 |
2000年 | 7篇 |
1999年 | 12篇 |
1998年 | 23篇 |
1997年 | 6篇 |
1996年 | 12篇 |
1995年 | 7篇 |
1994年 | 5篇 |
1993年 | 4篇 |
1992年 | 7篇 |
1991年 | 7篇 |
1990年 | 9篇 |
1989年 | 4篇 |
1988年 | 7篇 |
1987年 | 6篇 |
1986年 | 5篇 |
1985年 | 6篇 |
1984年 | 12篇 |
1983年 | 7篇 |
1982年 | 10篇 |
1981年 | 8篇 |
1980年 | 3篇 |
1979年 | 8篇 |
1977年 | 4篇 |
1976年 | 4篇 |
1975年 | 3篇 |
1973年 | 4篇 |
1972年 | 2篇 |
1956年 | 1篇 |
排序方式: 共有782条查询结果,搜索用时 193 毫秒
101.
Highly polymorphic genetic markers provide a useful tool for estimating important genetic parameters in studies of the evolution of sociality in insects. Here we report 14 polymorphic microsatellite markers developed in the ant Formica exsecta. The number of alleles found ranged between 3 and 18 per locus. These markers were developed for studying genetic population structure and mating structure in F. exsecta populations with varying social organizations (monogyne and polygyne types of societies). Cross‐species amplification indicated that some of the markers might be usable even in species belonging to different subfamilies. 相似文献
102.
Cecilia Odlind Ilkka Reenilä Pekka T Männistö Risto Juvonen Staffan Uhlén Joseph A Gogos Maria Karayiorgou Peter Hansell 《BMC physiology》2002,2(1):14-9
Background
The intrarenal natriuretic hormone dopamine (DA) is metabolised by catechol-O-methyltransferase (COMT) and monoamine oxidase (MAO). Inhibition of COMT, as opposed to MAO, results in a potent natriuretic response in the rat. The present study in anaesthetized homozygous and heterozygous COMT gene deleted mice attempted to further elucidate the importance of COMT in renal DA and sodium handling. After acute intravenous isotonic sodium loading, renal function was followed. 相似文献103.
We studied the effect of long-term nitrogen fertilisation on wood chemistry at two boreal sites in Finland: the northern site (Kemijärvi) and the southern site (Heinola). N-fertilisation was repeated in five-year intervals from the 1960s. Norway spruce (Picea abies L. Karst.) trees that had been planted in 1938 and 1954, in the northern and the southern site, respectively, were harvested in October 2002. Altogether 20 trees, in five different size classes, either unfertilised or fertilised, were felled. Wood sections at breast height, consisting of five consecutive annual rings, from six (Kemijärvi) or five (Heinola) points with different distances from the pith were examined. Differences in growth between the northern and southern sites were marked in favour of the southern site. In the northern site fertilisation had clearly increased the diameter growth, while in the southern site fertilisation had no effect. Nitrogen fertilisation resulted in slight changes in wood chemistry that included increased nitrogen concentrations in the northern site and extractives in the southern site. Stem wood had higher concentrations of extractives, starch, and uronic acids, and lower concentration of cellulose, in the northern than in the southern site. Changes in the stem wood chemistry along radial axis were marked. The changes in wood chemistry are discussed in relation to the physiological function and also how the changes can influence the suitability of wood for different end-use purposes. 相似文献
104.
Lihua Sun Jari Per?kyl? Anselmi Kovalainen Keith H. Ogawa Pekka J. Karhunen Kaisa M. Hartikainen 《PloS one》2016,11(2)
Transcranial extraocular light affects the brains of birds and modulates their seasonal changes in physiology and behavior. However, whether the human brain is sensitive to extraocular light is unknown. To test whether extraocular light has any effect on human brain functioning, we measured brain electrophysiology of 18 young healthy subjects using event-related potentials while they performed a visual attention task embedded with emotional distractors. Extraocular light delivered via ear canals abolished normal emotional modulation of attention related brain responses. With no extraocular light delivered, emotional distractors reduced centro-parietal P300 amplitude compared to neutral distractors. This phenomenon disappeared with extraocular light delivery. Extraocular light delivered through the ear canals was shown to penetrate at the base of the scull of a cadaver. Thus, we have shown that extraocular light impacts human brain functioning calling for further research on the mechanisms of action of light on the human brain. 相似文献
105.
Pekka H. Mäenpää 《Biochimica et Biophysica Acta (BBA)/General Subjects》1977,498(2):294-305
The phosphorylation of phosvitin in vitro by a cyclic nucleotide-independent protein kinase (phosvitin kinase) derived from rooster liver is markedly stimulated by the divalent cation, Mg2+. In addition, the activity is further stimulated by low concentrations of the polyamines putrescine, spermidine and spermine leading to higher rates of phosphate incorporation than could be obtained at any concentration of Mg2+. Spermine is inhibitory at higher concentrations. The polyamines shift the Mg2+ requirement for maximal activity to lower concentrations. The activity of a cyclic AMP-dependent histone kinase from beef heart is not altered by the presence of polyamines. Heparin is a potent inhibitor of phosvitin kinase but has no effect on histone kinase. Polyribonucleotides (polyadenylic acid and transfer RNA) inhibit both types of kinases, but the degree of inhibition of phosvitin kinase is variable and depends upon the type of the polyanion present. Spermidine and spermine, but not Mg2+, efficiently counteract the inhibitory action of heparin and tRNA. The results suggest that, also in vivo, naturally occurring polyamines and polyanions such ass tRNA may have a regulatory function on protein kinases. 相似文献
106.
107.
108.
Rob Tinch Rob Bugter Malgorzata Blicharska Paula Harrison John Haslett Pekka Jokinen Laurence Mathieu Eeva Primmer 《Biodiversity and Conservation》2018,27(7):1763-1788
Making a strong case for biodiversity protection is central to meeting the biodiversity targets in international agreements such as the CBD and achieving the UN Sustainable Development Goals. Effective arguments are needed to convince diverse actors that protection is worthwhile, and can play a crucial role in closing the implementation gap between biodiversity policy targets and outcomes. Drawing on a database of arguments from 11 European case studies, along with additional interview and case study material from all 13 case studies of the BESAFE project, we analysed relationships between potential and observed effectiveness of arguments. Our results show that strong logic, robustness, and timing of arguments are necessary but not sufficient conditions for arguments to be effective. We find that use of multiple and diverse arguments can enhance effectiveness by broadening the appeal to wider audiences, especially when arguments are repeated and refined through constructive dialogue. We discuss the role of framing, bundling and tailoring arguments to audiences in increasing effectiveness. Our results provide further support for the current shift towards recognition of value pluralism in biodiversity science and decision-making. We hope our results will help to demonstrate more convincingly the value of biodiversity to stakeholders in decision processes and thus build better cases for its conservation. 相似文献
109.
Pekka Jokinen Malgorzata Blicharska Eeva Primmer Ann Van Herzele Leena Kopperoinen Outi Ratamäki 《Biodiversity and Conservation》2018,27(7):1725-1740
Arguments in the formulation, implementation and evaluation of biodiversity policy frame conservation in a range of ways and express interests that can be conflicting. Policy processes are cyclic and iterative by nature and as policies are constantly reformulated, argumentation has an important role at each policy stage. In this paper, we utilise the policy cycle model to shed light on biodiversity-related policy processes and the ways in which argumentation generates effects at different stages of these processes. The paper first draws on literature and the theory-driven assumptions are then illustrated with insights from four European case studies on different policy processes in which biodiversity conservation plays a role. The analysis shows that argumentation tends to evolve over the course of the policy cycle, and framing has a key role across the different policy stages. It is concluded that the ways in which arguments persist, accumulate, diffuse, and replace old arguments, should be the target of increased attention in policy analysis. 相似文献
110.