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211.
Brandon S. Nichols Erika Chelales Roujia Wang Amanda Schulman Jennifer Gallagher Rachel A. Greenup Joseph Geradts Josephine Harter Paul K. Marcom Lee G. Wilke Nirmala Ramanujam 《Journal of biophotonics》2020,13(10)
Use of genomic assays to determine distant recurrence risk in patients with early stage breast cancer has expanded and is now included in the American Joint Committee on Cancer staging manual. Algorithmic alternatives using standard clinical and pathology information may provide equivalent benefit in settings where genomic tests, such as OncotypeDx, are unavailable. We developed an artificial neural network (ANN) model to nonlinearly estimate risk of distant cancer recurrence. In addition to clinical and pathological variables, we enhanced our model using intraoperatively determined global mammographic breast density (MBD) and local breast density (LBD). LBD was measured with optical spectral imaging capable of sensing regional concentrations of tissue constituents. A cohort of 56 ER+ patients with an OncotypeDx score was evaluated. We demonstrated that combining MBD/LBD measurements with clinical and pathological variables improves distant recurrence risk prediction accuracy, with high correlation ( r = 0.98) to the OncotypeDx recurrence score. 相似文献
212.
Durappanavar Prasada Ningappa Nadoor Prakash Waghe Prashantkumar Pavithra B. H. Jayaramu G. M. 《Biological trace element research》2019,190(1):124-139
Biological Trace Element Research - An experimental study was conducted in Wistar rats to characterize the arsenic (“As”)-induced alterations in neurobiochemistry in brain and its... 相似文献
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Experimental studies were carried out for upgrading the secondary treated domestic sewage effluent using the Rotating Biological Contactors (RBC) as an unit process in the premises of the existing water reclamation plant of Satellite Centre Building Complex of Indian Space Research Organisation at Bangalore. As part of these studies, a brief study was carried out on the microbiological aspects of the biological slime layer developed in the RBC. This study included observations on the development of the biological film on wetted disc surfaces of RBC, measurement of the thickness of the biological film, a discussion on significance of biofilm thickness in substrate removal, effect of wastewater characteristics on the thickness of biofilm and determination of MLSS/MLVSS ratio of biological film obtained in RBC reactor used for upgrading the secondary effluent. The results of these studies are presented in this paper. The results of identification of species of micro-organisms predominant in the biological slime layer in the RBC used for upgradation of secondary treated effluent are discussed separately in another paper. 相似文献
215.
The structure of a piece of silicified bark of Taxodioxylon gypsaceum from near Medicine Hat in Southern Alberta is described. The fossil specimen probably came from Upper Cretaceous beds. The fossil shows affinities with the bark of modern Sequoia. Vectia luccombensis Stopes (1915) from the Lower Greensand (Aptian) of England probably constitutes an isolated piece of taxodiaceous bark, similar to the inner bark of the Alberta specimen. 相似文献
216.
Medhini Madi Mathangi Kumar Pavithra Varchas Ravindranath Vineetha Kalyana Chakravarthy Pentapati 《Saudi Journal of Biological Sciences》2021,28(8):4437-4441
The coronavirus pandemic has caused a global public health crisis with an unprecedented shutdown of major establishments and non-emergency services. Disruptions across the country in dental hospitals led to challenges in addressing patient’s dental complaints. The present study aimed to analyse the difference in the pattern of the Outpatient dental visits during the pandemic period in comparison to that of the pre-pandemic period in a tertiary care hospital. This retrospective study was carried out by retrieving the patient data from the diagnostic register of the Department of Oral Medicine and Radiology for a period of one year. The data that was retrieved from 24th September 2019 to 23rd March 2020 was categorized under the pre-pandemic period and the data from 24th March 2020 to 24th September 2020 was grouped under the pandemic period. Patient data regarding the age, gender and clinical diagnosis was recorded and categorized under three main categories: “Emergency”, “urgent” and “elective”. 7550 patients during pre-pandemic period and 4035 patients during the pandemic period visited the dental hospital during the study period. Under the “emergency dental care” category, during the pre-pandemic period, majority of the cases reported of acute dental pain (71.0%) followed by cellulitis and space infection (20.1%) and maxillofacial trauma (8.7%). During the pandemic period, acute dental pain consisted of all emergency visits (n = 307). The proportion of emergency dental visits during the pandemic were significantly higher than the pre-pandemic period. Elective dental visits were significantly higher during pre-pandemic period in comparison to the pandemic period. (P < 0.001). There was a notable change in the outpatient trend of the dental visits during the COVID-19 pandemic in comparison to the pre-pandemic period. Emergency dental services were utilized at a higher rate during the pandemic period in comparison to the pre-pandemic counterpart. 相似文献
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Alwar Ramanujam Padmavathi Arindam Das Arumugam Priya T. J. Sushmitha Shunmugiah Karutha Pandian 《Biofouling》2020,36(1):56-72
AbstractThe effects of two prominent copper oxide nanoparticles (CuO-NP and Cu2O-NP), with the oxidation state of Cu++ (cupric) and Cu+ (cuprous), on Candida albicans were evaluated. CuO-NP and Cu2O-NP were synthesized and characterized by XRD, FESEM, HR-TEM and Zeta potential. At sub-MIC (50?µg ml?1), both cupric and cuprous oxide NPs prevented yeast-to-hyphae switching and wrinkling behaviour in C. albicans. The mechanism for the antifungal action of the two NPs differed; CuO-NP significantly elicited reactive oxygen species, whereas membrane damage was more pronounced with Cu2O-NP. Real time PCR analysis revealed that CuO-NP suppressed the morphological switching of yeast-to-hyphae by down-regulating cph1, hst7 and ras1 and by up-regulation of the negative regulator tup1. In comparison, Cu2O-NP resulted in down-regulation of ras1 and up-regulation of the negative regulators nrg1 and tup1. Between the two NPs, CuO exhibited increased antifungal activity due to its stable oxidation state (Cu++) and its smaller dimensions compared with Cu2O-NP. 相似文献
219.
Effect of salicylic acid on nodulation, nitrogenous compounds and related enzymes of Vigna mungo 总被引:3,自引:0,他引:3
Plants of Vigna mungo raised from seeds presoaked in salicylic acid (0.0, 0.01, 0.1 and 1.0 mM) and nodulated with the cowpea
strain of Rhizobium leguminosarum were analysed 15 and 30 d after sowing. The foliar nitrate and nitrite contents were varying
but soluble protein and total nitrogen contents were lower in treated than control plants. Nitrate reductase activity was
increased at the two lower concentrations of 0.01 and 0.1 mM but was inhibited at the highest concentration used (1.0 mM).
The number of nodules, their leghemoglobin and protein contents and nitrogenase activity of roots were reduced.
This revised version was published online in July 2006 with corrections to the Cover Date. 相似文献