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141.
Mei F Zhong J Yang X Ouyang X Zhang S Hu X Ma Q Lu J Ryu S Deng X 《Biomacromolecules》2007,8(12):3729-3735
Significant effort has been devoted to fabricating various biomaterials to satisfy specific clinical requirements. In this study, we developed a new type of guided tissue regeneration (GTR) membrane by electrospinning a suspension consisting of poly( l-lactic acid), multiwalled carbon nanotubes, and hydroxyapatite (PLLA/MWNTs/HA). MWNTs/HA nanoparticles were uniformly dispersed in the membranes, and the degradation characteristics were far improved. Cytologic research revealed that the PLLA/MWNTs/HA membrane enhanced the adhesion and proliferation of periodontal ligament cells (PDLCs) by 30% and inhibited the adhesion and proliferation of gingival epithelial cells by 30% also, compared with the control group. After PDLCs were seeded into the PLLA/MWNTs/HA membrane, cell/membrane composites were implanted into the leg muscle pouches of immunodeficient mice. Histologic examinations showed that PDLCs attached on the membranes functioned well in vivo. This new type of membrane shows excellent dual biological functions and satisfied the requirement of the GTR technique successfully in spite of a monolayer structure. Compared with other GTR membranes on sale or in research, the membrane can simplify the manufacturing process, reduce the fabrication cost, and avoid possible mistakes in clinical application. Moreover, it does not need to be taken out after surgery. PLLA/MWNTs/HA membranes have shown great potential for GTR and tissue engineering. 相似文献
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Guo Xiaoping Sun Junming Liang Jinning Zhu Siran Zhang Mingyuan Yang Lichao Huang Xuejing Xue Kangning Mo Zhongxiang Wen Sha Hu Bing Liu Jiajuan Ouyang Yiqiang He Min 《Molecular biology reports》2022,49(10):9335-9344
Molecular Biology Reports - Lung injury caused by pulmonary inflammation is one of the main manifestations of respiratory diseases. Vasorin (VASN) is a cell-surface glycoprotein encoded by the VASN... 相似文献
144.
Yong Liang De-Yun Zhang Shuhong Ouyang Jingzhong Xie Qiuhong Wu Zhenzhong Wang Yu Cui Ping Lu Dong Zhang Zi-Ji Liu Jie Zhu Yong-Xing Chen Yan Zhang Ming-Cheng Luo Jan Dvorak Naxin Huo Qixin Sun Yong-Qiang Gu Zhiyong Liu 《TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik》2015,128(8):1617-1629
145.
Chaoyu Cui Junxi Jiang Hui Ouyang Cheng Li Dengquan Liu Ting Huang 《Journal of Phytopathology》2015,163(9):780-782
In 2013, bitter rot of grape was observed in Changbei Vineyard located in Nanchang City, Jiangxi Province, China. Greeneria species was consistently isolated from the diseased grape berries (Vitis labruscana cv. Kyoho) at approximately 91% of isolation rate in three independent experiments. The species was identified as Greeneria uvicola based on the morphological characteristics, cultural appearance and sequence analysis. Koch's postulates were fulfilled through pathogenicity tests on detached healthy Kyoho grape berries. To our knowledge, this is the first report of G. uvicola causing bitter rot of grape in China. 相似文献
146.
Plant lectins,from ancient sugar‐binding proteins to emerging anti‐cancer drugs in apoptosis and autophagy 下载免费PDF全文
Q.‐L. Jiang S. Zhang M. Tian S.‐Y. Zhang T. Xie D.‐Y. Chen Y.‐J. Chen J. He J. Liu L. Ouyang X. Jiang 《Cell proliferation》2015,48(1):17-28
Ubiquitously distributed in different plant species, plant lectins are highly diverse carbohydrate‐binding proteins of non‐immune origin. They have interesting pharmacological activities and currently are of great interest to thousands of people working on biomedical research in cancer‐related problems. It has been widely accepted that plant lectins affect both apoptosis and autophagy by modulating representative signalling pathways involved in Bcl‐2 family, caspase family, p53, PI3K/Akt, ERK, BNIP3, Ras‐Raf and ATG families, in cancer. Plant lectins may have a role as potential new anti‐tumour agents in cancer drug discovery. Thus, here we summarize these findings on pathway‐ involved plant lectins, to provide a comprehensive perspective for further elucidating their potential role as novel anti‐cancer drugs, with respect to both apoptosis and autophagy in cancer pathogenesis, and future therapy. 相似文献
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