全文获取类型
收费全文 | 102篇 |
免费 | 9篇 |
出版年
2021年 | 7篇 |
2020年 | 1篇 |
2018年 | 1篇 |
2017年 | 3篇 |
2016年 | 6篇 |
2015年 | 4篇 |
2014年 | 4篇 |
2013年 | 5篇 |
2012年 | 8篇 |
2011年 | 8篇 |
2010年 | 2篇 |
2009年 | 5篇 |
2008年 | 5篇 |
2007年 | 6篇 |
2006年 | 4篇 |
2005年 | 3篇 |
2004年 | 1篇 |
2002年 | 6篇 |
2001年 | 2篇 |
2000年 | 3篇 |
1999年 | 1篇 |
1998年 | 10篇 |
1997年 | 2篇 |
1996年 | 2篇 |
1986年 | 1篇 |
1982年 | 2篇 |
1980年 | 1篇 |
1977年 | 3篇 |
1976年 | 2篇 |
1972年 | 2篇 |
1971年 | 1篇 |
排序方式: 共有111条查询结果,搜索用时 375 毫秒
51.
52.
53.
Amira Bidani Oumèma Nouri-Ellouz Lilia Lakhoua Darasinh Sihachakr Catherine Cheniclet Ali Mahjoub Noureddine Drira Radhia Gargouri-Bouzid 《Plant Cell, Tissue and Organ Culture》2007,91(3):179-189
In this study three somatic hybrid lines originating from protoplast fusion between Solanum tuberosum cv. BF15 and Solanum berthaultii were subjected to a detailed molecular analysis using the I-SSR-PCR technique based on 5′-anchored microsatellite primers.
The data obtained revealed a polymorphism between the different lines, suggesting that they correspond to symmetric hybrids.
The analysis of chloroplast genome of these hybrids showed that they are resulting from a recombination between parental plastomes.
When transferred to a greenhouse, these hybrid lines displayed an improved vigour compared to the cultivated potato BF15 parent.
Indeed, an important growth rate and high tuber yield and weight were obtained for these hybrids compared to the parent. Some
of these hybrids showed also an improved ion homeostasis control and they seem to display a better tolerance to salt stress
compared to the potato BF15 parent. 相似文献
54.
It is commonly assumed that creatine kinase (CK) activity in plasma is related to the state of an inflammatory response at 24-48 h, and also it has shown biphasic patterns after a marathon run. No information is available on CK isoenzymes after an ultra-marathon run. The purpose of the present study is to examine the CK isoenzymes after a 200 km ultra-marathon run and during the subsequent recovery. Blood samples were obtained during registration 1 2 h before the 200-km race and during the race at 100 km, 150 km and at the end of 200 km, as well as after a 24 h period of recovery. Thirty-two male ultra-distance runners participated in the study. Serum CPK showed a marked increase throughout the race and 24 h recovery period (p < 0.001). Serum CK during the race occurs mostly in the CK-MM isoform and only minutely in the CK-MB isoform and is unchanged in the CK-BB isoform. High-sensitivity C-reactive protein (hs-CRP), oestradiol, AST and ALT increased significantly from the pre-race value at 100 km and a further increase took place by the end of the 200 km run. The results of our study demonstrate a different release pattern of creatine kinase after an ultra-distance (200 km) run compared to the studies of marathon running and intense eccentric exercise, and changes in several biomarkers, indicative of muscle damage during the race, were much more pronounced during the latter half (100–200 km) of the race. However, the increases in plasma concentration of muscle enzymes may reflect not only structural damage, but also their rate of clearance. 相似文献
55.
Background
Protein remote homology detection is a central problem in computational biology. Most recent methods train support vector machines to discriminate between related and unrelated sequences and these studies have introduced several types of kernels. One successful approach is to base a kernel on shared occurrences of discrete sequence motifs. Still, many protein sequences fail to be classified correctly for a lack of a suitable set of motifs for these sequences. 相似文献56.
Treatment with the chimerical monoclonal antibody rituximab results in CD20-directed B cell depletion. Although this depletion
is almost complete in the peripheral blood of nearly all patients with rheumatoid arthritis, a proportion of patients does
not exhibit a clinical response. The paper by Nakou and colleagues suggests that a decrease in CD19+CD27+ memory B cells in
both peripheral blood and bone marrow precedes the clinical response to rituximab. This finding adds to the emerging evidence
that lack of response to rituximab is associated with persistence of B lineage cells in specific body compartments. 相似文献
57.
Ibtissem Louiz Oum Kalthoum Ben Hassine Olivier Palluel Mossadok Ben-Attia Wafa Gaddacha Sélim Aït-Aïssa 《Biological Rhythm Research》2017,48(6):963-977
This study assessed seasonal variation of total liver proteins level (LPLs) and biotransformation biomarkers in two fish species, G. niger and Z. ophiocephalus, during a one year-survey in the low contaminated Ghar-El-Melh lagoon, Tunisia. Analyzed biomarkers were compared with physiological indexes such as the condition index, hepato-somatic index, and gonado-somatic index and environmental parameters. A significant annual rhythms of glutathione-S-transferase and ethoxyresorufin-O-deethylase activities were validated by cosinor. The highest peak (acrophase) of activities occurred in summer likely related to the elevated seawater temperature. Midline Estimating Statistic of Rhythm and amplitudes were higher in Z. ophiocephalus than in G. niger. The results showed, as well, an acrophase of (LPLs) in spring coinciding with reproductive period in Z. ophiocephalus and beginning of reproductive period in G. niger. This study established a baseline for the selected enzymatic activities in gobies, which required information for a correct interpretation of biomarker responses in environmental monitoring. 相似文献
58.
59.
JH Shazia Fathima Jayaraman Selvaraj Venkatacalam Sivabalan Umapathy Vidhya Rekha Rajagopal Ponnulakshmi Veeraraghavan Vishnupriya Malathi Kullappan Radhika nalinakumari Sreekandan Surapaneni Krishna Mohan 《Bioinformation》2021,17(1):206
Matrix metalloproteinase protein-2 (MMP-2) is linked to the human oral squamous cell carcinoma. Therefore, it is of interest to design new inhibitors for MMP-2 to combat the disease. Thus, we document the molecular docking features of Aristolochic acid, Cryptopleurine, Epipodophyllotoxin, and Fagaronine with MMP-2 for further consideration. 相似文献
60.
Catherine C Beauheim Farrell Wymore Michael Nitzberg Zachariah K Zachariah Heng Jin JH Pate Skene Catherine A Ball Gavin Sherlock 《BMC bioinformatics》2007,8(1):338