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81.
Adebayo Olusegun G. Aduema Wadioni Emmanuel Modo U. Ben-Azu Benneth Orji Blessing O. Akpakpan Ekam Adebayo Oluwakemi Rachael Onuoha Ogechukwu G. Ajayi Abayomi M. 《Neurochemical research》2022,47(8):2211-2229
Neurochemical Research - Activation of nuclear factor erythroid 2 related factor 2 (Nrf2) associated with the suppression of various oxido-inflammatory pathways and the controller of several gene... 相似文献
82.
Biocompatibility and Conductometric Property of Sol-Gel Derived ZnO/PVP Nanocomposite Biosensor Film
Nanocrystalline ZnO and ZnO/PVP nanocomposite films have been prepared by the sol-gel dip-coating technique from zinc acetate precursor on silicon wafer and Pyrex glass substrates. The films were characterized using atomic force microscopy for morphology, and X-ray photoelectron spectroscopy and Fourier transform infrared spectroscopy for chemical analysis. Thermally untreated and annealed films were studied in order to analyze the influence of temperature on the formation and properties of the films. The films have a uniform void-free surface and the grain size increases with the annealing temperature. The cell viability assays indicate that the growth rate of BPH cells incubated in the presence of ZnO was significantly reduced (35% of the control) compared to that of untreated controls, indicating antibacterial activity of ZnO as a result of the generation of hydrogen peroxide. The sensor characteristic of ZnO/PVP nanocomposite was also demonstrated by measuring the change in conductivity upon exposure to superoxide anion radical. 相似文献
83.
Ahmad Al-Serri Suzanne A. Al-Bustan Salman K. Al-Sabah Babitha G. Annice Majed A. Alnaqeeb Olusegun A. Mojiminiyi 《Saudi Journal of Biological Sciences》2021,28(8):4717-4722
Lipoprotein lipase (LPL) is an enzyme involved in lipid metabolism and distribution of fatty acids hence its role in the initiation and development of dyslipidemia and adiposity. Single nucleotide polymorphisms (SNPs) across the LPL gene have been associated with dyslipidemia, however, the association with obesity has been limited towards specific populations. This study examined the association between LPL gene polymorphisms with plasma lipid levels and body mass index (BMI) in the Kuwaiti population. We examined a total of 486 adults (303 and 183 females and males respectively) with plasma lipid levels and BMI. DNA samples were genotyped for two LPL gene polymorphisms (rs1534649 and rs28645722) using TaqMan allelic discrimination. The relationship between the genotypes with both plasma lipid levels and BMI were assessed using linear regression using “SNPassoc” package from R statistical software. Using an additive genetic model, linear regression analysis showed the T-allele of rs1534649 to be associated with increased BMI in a dose-dependent trend β = 2.13 (95% CI 1.33–2.94); p = 1.7 × 10?7. In addition, a borderline significance was observed between the T-allele and low levels of high density lipoprotein-cholesterol β = ?0.04 (95% CI ?0.08, ?0.006); p = 0.02. There were no associations between rs28645722 and plasma lipid levels (p > 0.05). However, a trend was observed between the A-allele and increased BMI β = 1.75 (95% CI 0.14–3.35); p = 0.03. Our study shows intron one polymorphism rs1534649 to increase the risk of obesity and dyslipidemia. Our findings warrant further investigation of the mechanism of LPL on the development of obesity along with the role of intron one and its impact on LPL gene activity. 相似文献
84.
Olusegun O. Osunkoya Christine Perrett Chandima Fernando Cameron Clark S. Raghu 《Plant Ecology》2012,213(6):883-897
As with many invasive plant species, little is known of the population spatial patterns and stand dynamics of Lantana camara L. (Verbenaceae)??a thicket-forming weed of worldwide significance in managed and conservation lands, including coastal and inland habitats of Eastern Australia. Consequently, we mapped and followed annually for 3?years the demographic fate of more than 2000 Lantana individuals at sites with four land-uses (hoop pine plantation, cattle farm, and two eucalyptus forests with occasional grazing and periodic burning regime, respectively) in Queensland, SE Australia. Populations exhibited plant size distributions that were continuous (i.e., of L or symmetric type) and unimodal, except the farm population where bimodality was observed. Newly established plants could be reproductive within one growing season at ~50?cm in height, especially where environmental resources were not limiting. Density had an appreciable effect on the weed??s reproductive capacity and growth, but not on survival. Established and newly recruited individuals were aggregated but the degree of aggregation decreased with plant size. However, in the sites that had experienced burning or mechanical clearing, Lantana seedling/juvenile recruitment assumed negative association (spatial displacement) in relation to established individuals. The findings of this study agree with the notion that ecological processes often leave characteristic spatial signatures, which if interpreted using appropriate hypotheses can help to ascertain factors responsible for the observed spatial patterns and stand dynamics. 相似文献
85.
Journal of Mathematical Biology - A recent parameter identification technique, the local lagged adapted generalized method of moments, is used to identify the time-dependent disease transmission... 相似文献
86.
Salka Ndazo Minka Joseph Olusegun Ayo 《Journal of applied animal welfare science : JAAWS》2013,16(3):272-288
This study investigated the effects of 12 hr of road transportation during the hot-dry conditions and the modulating role of ascorbic acid (AA) on the hydration state of goats. Twenty goats who served as treatment goats received oral administration of 100 mg/kg body weight of AA, whereas another 20 control goats received sterile water; thereafter, the goats were loaded and transported. The study determined changes in skin thickness; albumin (Alb); total protein (TP); elimination of the gut content; fecal water; urine specific gravity (SG); and pH before, during, and after the transportation. The result obtained in the control goats showed significant (p < .05) increases in the values of TP, Alb, urine SG, and pH; elimination; and drinking behavior, whereas skin thickness decreased over transportation. In the treatment goats who were administered AA, the changes observed in the values were insignificant (p > .05). In conclusion, 12-hr road transportation of goats induced dehydration, which may affect the welfare and health status of the goats. The administration of AA ameliorated the risk of adverse effects of handling, loading, transportation, and hot-dry conditions on hydration state of goats. 相似文献