全文获取类型
收费全文 | 101篇 |
免费 | 19篇 |
出版年
2022年 | 1篇 |
2018年 | 1篇 |
2016年 | 1篇 |
2015年 | 5篇 |
2014年 | 3篇 |
2013年 | 6篇 |
2012年 | 4篇 |
2011年 | 4篇 |
2010年 | 2篇 |
2009年 | 7篇 |
2008年 | 5篇 |
2007年 | 5篇 |
2006年 | 4篇 |
2005年 | 3篇 |
2004年 | 3篇 |
2003年 | 4篇 |
2002年 | 1篇 |
2001年 | 4篇 |
2000年 | 2篇 |
1999年 | 4篇 |
1998年 | 2篇 |
1997年 | 4篇 |
1996年 | 1篇 |
1995年 | 3篇 |
1994年 | 2篇 |
1993年 | 1篇 |
1991年 | 1篇 |
1990年 | 2篇 |
1989年 | 4篇 |
1987年 | 1篇 |
1986年 | 1篇 |
1985年 | 1篇 |
1984年 | 1篇 |
1983年 | 1篇 |
1982年 | 1篇 |
1981年 | 4篇 |
1980年 | 1篇 |
1979年 | 3篇 |
1977年 | 4篇 |
1976年 | 1篇 |
1975年 | 2篇 |
1973年 | 1篇 |
1972年 | 1篇 |
1970年 | 1篇 |
1968年 | 1篇 |
1965年 | 1篇 |
1963年 | 2篇 |
1960年 | 1篇 |
1959年 | 1篇 |
1949年 | 1篇 |
排序方式: 共有120条查询结果,搜索用时 0 毫秒
21.
Differences in risk factors for second and third degree hypospadias in the national birth defects prevention study
下载免费PDF全文
![点击此处可从《Birth defects research. Part A, Clinical and molecular teratology》网站下载免费的PDF全文](/ch/ext_images/free.gif)
22.
Ethanol-induced neuronal apoptosis in vivo requires BAX in the developing mouse brain 总被引:8,自引:0,他引:8
Young C Klocke BJ Tenkova T Choi J Labruyere J Qin YQ Holtzman DM Roth KA Olney JW 《Cell death and differentiation》2003,10(10):1148-1155
A single episode of ethanol intoxication triggers widespread apoptotic neurodegeneration in the infant rat or mouse brain. The cell death process occurs over a 6-16 h period following ethanol administration, is accompanied by a robust display of caspase-3 enzyme activation, and meets ultrastructural criteria for apoptosis. Two apoptotic pathways (intrinsic and extrinsic) have been described, either of which may culminate in the activation of caspase-3. The intrinsic pathway is regulated by Bax and Bcl-XL and involves Bax-induced mitochondrial dysfunction and release of cytochrome c as antecedent events leading to caspase-3 activation. Activation of caspase-8 is a key event preceding caspase-3 activation in the extrinsic pathway. In the present study, following ethanol administration to infant mice, we found no change in activated caspase-8, which suggests that the extrinsic pathway is not involved in ethanol-induced apoptosis. We also found that ethanol triggers robust caspase-3 activation and apoptotic neurodegeneration in C57BL/6 wildtype mice, but induces neither phenomenon in homozygous Bax-deficient mice. Therefore, it appears that ethanol-induced neuroapoptosis is an intrinsic pathway-mediated phenomenon involving Bax-induced disruption of mitochondrial membranes and cytochrome c release as early events leading to caspase-3 activation. 相似文献
23.
24.
25.
The calculation of net ankle, knee, and hip joint reaction forces is an often applied procedure in the analysis of gait. Except for very few studies, joint reaction forces have not been measured in other joints such as the fingers, wrist, elbow, shoulder and toes. In this study the joint reaction forces between the metatarsal head and the proximal phalanx and the metatarsal head and the sesamoids are calculated for the push off phase during gait. The results of ten normal elderly subjects show that the maximum resultant loads of the two articulations lie close to the longitudinal axis of the metatarsal. The knowledge of the magnitude and direction of the joint reaction forces of a normal elderly population will be essential for the design of an optimal fixation of an artificial anatomical first MTP joint. 相似文献
26.
JW Santo Domingo J C Radway E W Wilde P Hermann T C Hazen 《Journal of industrial microbiology & biotechnology》1997,18(6):389-395
Immobilization of the trichloroethylene-degrading bacterium Burkholderia cepacia was evaluated using hydrophilic polyurethane foam. The influence of several foam formulation parameters upon cell retention
was examined. Surfactant type was a major determinant of retention; a lecithin-based compound retained more cells than pluronic-
or silicone-based surfactants. Excessive amounts of surfactant led to increased washout of bacteria. Increasing the biomass
concentration in the foam from 4.8 to 10.5% dry weight per wet weight of foam resulted in fewer cells being washed out. Embedding
at reduced temperature did not significantly affect retention, while the use of a silane binding agent gave inconsistent
results. The optimal formulation retained all but 0.2% of total embedded cells during passage of 2 L of water through columns
containing 2 g of foam. All foam formulations tested reduced the culturability of embedded cells by several orders of magnitude,
but O2 consumption and CO2 evolution rates of embedded cells were never less than 50% of those of free cells. Nutrient amendments stimulated an increase
in cell volume and ribosomal activity in immobilized cells as indicated by hybridization studies using fluorescently labeled
ribosomal probes. These results indicate that, although immobilized cells were mostly nonculturable, they were metabolically
active and thus could be used for biodegradation of toxic compounds.
Received 23 December 1996/ Accepted in revised form 13 March 1997 相似文献
27.
Restriction-map variation associated with the G6PD polymorphism in natural populations of Drosophila melanogaster 总被引:10,自引:0,他引:10
Restriction-map variation was studied in 126 copies of the G6pd region in X
chromosome lines of Drosophila melanogaster from North America, Europe, and
Africa. Special attention was focused on the distribution of variation
relative to the geographically variable polymorphism for two
electrophoretic variants. Nucleotide heterozygosity as determined by eight
six-cutter restriction enzymes for the 13-kb region is estimated, on the
basis of the worldwide sample, to be 0.065%, which is the lowest value
reported for any comparable region in the D. melanogaster genome.
Significant linkage disequilibrium between electrophoretic alleles and
restriction-site variation is observed for several sites. In contrast to
published studies of other genetic regions, there are large insertions that
reach significant frequencies and are found across considerable geographic
distances. There is a clustering of this variation inside the first large
intervening sequence of the G6PD gene.
相似文献
28.
29.
P. J. S. Olney 《Ibis》1963,105(1):55-62
The food and feeding habits of Tufted Duck Aythya fuligula are described, based on field observations and on the analyses of the stomach contents of 95 birds, all but one of them having fed inland; 57 were collected from a gravel pit near London, 28 from Northern Ireland and 9 from a number of English inland waters, in the shooting seasons 1959-60 and 1960-61.
The London birds in both seasons had fed primarily on molluscs, mainly Dreissena polymorpha. The Northern Ireland birds, where D. polymorpha does not occur, had a more variable diet, again mainly molluscs, but with some crustaceans, insects and plant seeds. The English birds had a similarly variable diet with the emphasis on crustaceans ( Asellus spp.) and with some molluscs, insects and plant seeds. Brief information is given on the food of young birds.
It is suggested that the spread of D. polymorpha may be one of the factors explaining the recent spread of the Tufted Duck in certain areas. It appears that where one particular food such as D. polymorpha is not plentiful a more variable diet is taken, though molluscs always figure prominently. The type of food taken depends on the type of habitat used, the availability and size of the food items and on the methods of feeding. 相似文献
The London birds in both seasons had fed primarily on molluscs, mainly Dreissena polymorpha. The Northern Ireland birds, where D. polymorpha does not occur, had a more variable diet, again mainly molluscs, but with some crustaceans, insects and plant seeds. The English birds had a similarly variable diet with the emphasis on crustaceans ( Asellus spp.) and with some molluscs, insects and plant seeds. Brief information is given on the food of young birds.
It is suggested that the spread of D. polymorpha may be one of the factors explaining the recent spread of the Tufted Duck in certain areas. It appears that where one particular food such as D. polymorpha is not plentiful a more variable diet is taken, though molluscs always figure prominently. The type of food taken depends on the type of habitat used, the availability and size of the food items and on the methods of feeding. 相似文献
30.