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971.
972.
Atsushi Takeda Jinko Sawashita Sachiyo Takefuta Shoji Okada 《Biological trace element research》1998,61(1):71-78
To study the relationship between tissue accumulation of Zinc (Zn) and neurodegeneration in the nigrostriatal dopaminergic
pathway,65Zn distribution in this pathway was examined after unilateral injection of 6-hydroxydopamine (6-OHDA) into the substantia
nigra of rats. When65ZnCl2 was intravenously injected 4 days after treatment with 6-OHDA,65Zn was concentrated in the ipsilateral substantia nigra 6 days after65Zn injection. On the other hand, 19 d after treatment with 6-OHDA,65Zn distribution in the ipsilateral substantia nigra was decreased to the level of the contralateral one. When NH4
99TcO4, which cannot go through the blood-brain barrier, was injected into rats 4 d after treatment with 6-OHDA,99Tc was concentrated in the ipsilateral substantia nigra 30 min after99Tc injection, but no longer detectable 6 d after injection. These results suggest that Zn is necessary for a repair process
called replacement gliosis after the death of neurons and that excess Zn does not accumulate in the lesion after completion
of the gliosis. 相似文献
973.
Tsutomu Takayanagi Gentaro Okada Seiya Chiba 《Bioscience, biotechnology, and biochemistry》2013,77(9):2337-2341
A gas-liquid chromatographic method was applied to the determination of anomeric forms of isomaltose and glucose produced by Arthrobacter globiformis isomalto-dextranase and glucodex- tranase. The anomeric forms of products released from isomaltotriose, panose and dextran were quantitatively determined. The isomalto-dextranase that was also capable of splitting the α-1,4- glucosidic linkage of panose was found to exclusively produce α-isomaltose from these substrates, and the glucodextranase, ^-glucose. 相似文献
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976.
Kenichi Tomi Makiko Kitao Norihiro Konishi Hiroshi Murakami Yasuki Matsumura Takahiro Hayashi 《Bioscience, biotechnology, and biochemistry》2016,80(5):840-847
Essential oils and hydrosols were extracted from rosemary harvested in different seasons, and the chemical compositions of volatile components in the two fractions were analyzed by gas chromatography–mass spectrometry (GC–MS). Enantiomers of some volatile components were also analyzed by enantioselective GC–MS. Classification of aroma components based on chemical groups revealed that essential oils contained high levels of monoterpene hydrocarbons but hydrosols did not. Furthermore, the enantiomeric ratios within some volatile components were different from each other; for example, only the (S)-form was observed for limonene and the (R)-form was dominant for verbenone. These indicate the importance of determining the enantiomer composition of volatile components for investigating the physiological and psychological effects on humans. Overall, enantiomeric ratios were determined by volatile components, with no difference between essential oils and hydrosols or between seasons. 相似文献
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979.
980.
Motoki Watabe Takahiro A. Kato Alan R. Teo Hideki Horikawa Masaru Tateno Kohei Hayakawa Norihiro Shimokawa Shigenobu Kanba 《PloS one》2015,10(4)
Maladaptive social interaction and its related psychopathology have been highlighted in psychiatry especially among younger generations. In Japan, novel expressive forms of psychiatric phenomena such as “modern-type depression” and “hikikomori” (a syndrome of severe social withdrawal lasting for at least six months) have been reported especially among young people. Economic games such as the trust game have been utilized to evaluate real-world interpersonal relationships as a novel candidate for psychiatric evaluations. To investigate the relationship between trusting behaviors and various psychometric scales, we conducted a trust game experiment with eighty-one Japanese university students as a pilot study. Participants made a risky financial decision about whether to trust each of 40 photographed partners. Participants then answered a set of questionnaires with seven scales including the Lubben Social Network Scale (LSNS)-6 and the Patient Health Questionnaire (PHQ)-9. Consistent with previous research, male participants trusted partners more than female participants. Regression analysis revealed that LSNS-family (perceived support from family) for male participants, and item 8 of PHQ-9 (subjective agitation and/or retardation) for female participants were associated with participants’ trusting behaviors. Consistent with claims by social scientists, our data suggest that, for males, support from family was negatively associated with cooperative behavior toward non-family members. Females with higher subjective agitation (and/or retardation) gave less money toward males and high attractive females, but not toward low attractive females in interpersonal relationships. We believe that our data indicate the possible impact of economic games in psychiatric research and clinical practice, and validation in clinical samples including modern-type depression and hikikomori should be investigated. 相似文献