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611.
Rae-Hyun Kim Yowhan Son Jong Hwan Lim Im Kyun Lee Kyung Won Seo Jin Woo Koo Nam Jin Noh Soung-Ryoul Ryu Sun Kee Hong Byung Sun Ihm 《Ecological Research》2006,21(6):819-827
Coarse woody debris (CWD) is an essential component of forests. However, quantification of both the mass and nutrient content
of CWD within a given environment tends to be a fairly labor-intensive proposition that requires long-term studies to be conducted
for viable data to be obtained. As a result, various aspects of CWD in forest ecosystems remain somewhat poorly understood.
In this review, we have compiled all available estimates of CWD mass and nutrients from both coniferous and deciduous forests
in Korea. The CWD mass data varied substantially by forest type, age, location, and sampling time, ranging from 1.5 to 24.5 Mg ha−1, and for the amount (kg ha−1) of nutrients in the CWD, ranging from 3.5 to 23.6 for nitrogen (N), 0.8 to 4.7 for phosphorus (P), 3.9 to 13.3 for potassium
(K), 25.9 to 30.9 for calcium (Ca), 1.4 to 4.2 for magnesium (Mg), and 0.1 to 0.6 for sodium (Na). The mass of CWD transferred
from live trees to the forest floor ranged between 0.1 and 4.9 Mg ha−1 year−1, and these values were roughly equivalent to 26–42% of the annual litterfall inputs (2.5–10.8 Mg ha−1 year−1) for mixed Quercus spp. forests within the relevant region. Annual nutrients inputs (kg ha−1 year−1) through CWD decomposition were 0.7–1.6 for N, 0.04–0.3 for P, 0.3–1.0 for K, 1.7–3.1 for Ca, and 0.1–0.3 for Mg. Consequently,
these results revealed that the ecological value of CWD for C and nutrient cycling was relatively insignificant. However,
only a limited number of studies have been conducted on CWD in different coniferous or mixed deciduous forests in the region.
As a direct result of this paucity of data, further long-term studies on CWD mass and nutrients in a variety of forest types
are required in order to be able to evaluate accurately the ecological value of CWD on biodiversity and physical properties
in Korean forest ecosystems. 相似文献
612.
Jung Hwa Lim Hyun Mi Kang Hong-Ryul Jung Dae-Soo Kim Kyung Hee Noh Tae Kyung Chang Byoung Joon Kim Duk Hyun Sung Hyun-Soo Cho Kyung-Sook Chung Nam-Soon Kim Cho-Rok Jung 《生物化学与生物物理学报:疾病的分子基础》2018,1864(10):3221-3233
The spastin protein (SPAST) contains an ATPase with diverse cellular activities (AAA) domain and regulates microtubule dynamics. Missense mutations of the SPAST gene are frequently detected in patients with hereditary spastic paraplegias (HSPs) and represent the main reason of loss of SPAST function; however, the pathogenicity of mutant SPAST is heterogeneous. Here, SPAST variant with an I344K mutation (I344K-SPAST) was identified in a Korean family with autosomal dominant-type HSP. We investigated the role of the I344K-SPAST in HSP to provide a therapeutic mechanism. The I344K-SPAST mutation prolonged the half-life of the protein compared to wild-type SPAST (WT-SPAST) in cells by modulating post-translational modifications for proteasomal degradation. I344K-SPAST was localized in microtubule but defective in microtubule severing and ATPase activity compared to WT-SPAST in vitro and in cells. Mutant M87 isoform harboring the same mutation with I344K-M1 SPAST also increased protein stability and loss of MT severing activity, but the pathogenicity was not stronger than I344K-M1 SPAST in neurite outgrowth. Overexpression of I344K-SPAST resulted in microtubule accumulation following inhibited neurite growth in neuroblastoma, neural progenitor cells and mouse primary cortical neurons. Conversely, these pathogenic effects of I344K-SPAST were reduced by overexpression of WT-M1 SPAST in a dose dependent manner since WT-SPAST could interact with I344K-SPAST. Our data therefore provide proof-of-concept that gene transfer of WT-M1 SPAST may serve as a valid therapeutic option for HSPs. 相似文献
613.
Should we have different expectations regarding the likelihood and pace of speciation by sexual selection when considering species with sexually monomorphic mating signals? Two conditions that can facilitate rapid species divergence are Felsenstein's one‐allele mechanism and a genetic architecture that includes a genetic association between signal and preference loci. In sexually monomorphic species, the former can manifest in the form of mate choice based on phenotype matching. The latter can be promoted by selection acting upon genetic loci for divergent signals and preferences expressed simultaneously in each individual, rather than acting separately on signal loci in males and preference loci in females. Both sexes in the Chrysoperla carnea group of green lacewings (Insecta, Neuroptera, Chrysopidae) produce sexually monomorphic species‐specific mating signals. We hybridized the two species C. agilis and C. carnea to test for evidence of these speciation‐facilitating conditions. Hybrid signals were more complex than the parents and we observed a dominant influence of C. carnea. We found a dominant influence of C. agilis on preferences in the form of hybrid discrimination against C. carnea. Preferences in hybrids followed patterns predicting preference loci that determine mate choice rather than a one‐allele mechanism. The genetic association between signal and preference we detected in the segregating hybrid crosses indicates that speciation in these species with sexually monomorphic mating signals can have occurred rapidly. However, we need additional evidence to determine whether such genetic associations form more readily in sexually monomorphic species compared to dimorphic species and consequently facilitate speciation. 相似文献
614.
When root temperature dropped below 25°C, there was a sharp drop in the root pressure ( P r ) and hydraulic conductivity of excised roots ( Lp r ) of young cucumber ( Cucumis sativus L.) seedlings as measured with the root pressure probe. A detailed analysis of root hydraulics provided evidence for a larger reduction in the osmotic component of Lp r (77%) in comparison with the hydrostatic component (34%) in response to the exposure of the root system to 13°C. The activity of the plasma membrane H+ -ATPase (EC 3.6.1.35) was reduced from 30 to 16 µmol Pi mg−1 protein h−1 upon exposure to 8°C for 1 day. Ultrastructural observations showed no evidence of loosening of the microstructure of endodermal cell walls in low temperature (LT)-treated roots. It is concluded that the rapid drop in the P r in response to LT is largely caused by a reduction in the activity of the plasma membrane H+ -ATPase rather than by loosening of the endodermal wall which would cause substantial solute losses. On the other hand, water permeability of root cell membrane at LT was related to changes in the activity (open/closed state) of water channels. 相似文献
615.
616.
Kum Hee Noh Song-Hee Lee Haeri Lee Ae Jin Jeong Kyu Oh Kim Hyun Mu Shin Hang-Rae Kim Myung-Jin Park Jong Bae Park Jiyoung Lee Sang-Kyu Ye 《Translational oncology》2022,15(1)
The resistance of highly aggressive glioblastoma multiforme (GBM) to chemotherapy is a major clinical problem resulting in a poor prognosis. GBM contains a rare population of self-renewing cancer stem cells (CSCs) that proliferate, spurring the growth of new tumors, and evade chemotherapy. In cancer, major vault protein (MVP) is thought to contribute to drug resistance. However, the role of MVP as CSCs marker remains unknown and whether MVP could sensitize GBM cells to Temozolomide (TMZ) also is unclear. We found that sensitivity to TMZ was suppressed by significantly increasing the MVP expression in GBM cells with TMZ resistance. Also, MVP was associated with the expression of other multidrug-resistant proteins in tumorsphere of TMZ-resistant GBM cell, and was highly co-expressed with CSC markers in tumorsphere culture. On the other hands, knockdown of MVP resulted in reduced sphere formation and invasive capacity. Moreover, high expression of MVP was associated with tumor malignancy and survival rate in glioblastoma patients. Our study describes that MVP is a potentially novel maker for glioblastoma stem cells and may be useful as a target for preventing TMZ resistance in GBM patients. 相似文献
617.
While effectively attenuating neuronal apoptosis in mouse cortical culture, insulin paradoxically induced neuronal necrosis with 48 h of exposure. The insulin neurotoxicity was blocked by an antioxidant but not by caspase inhibitors. Exposure to insulin led to tyrosine phosphorylation of the insulin receptor and the insulin-like growth factor-1 (IGF-1) receptor and activation of protein kinase C (PKC) and phosphoinositide 3-kinase (PI3-kinase). Inhibitors of tyrosine kinase and PKC, but not PI3-kinase, attenuated the insulin neurotoxicity. Conversely, the inhibitor of PI3-kinase but not PKC reversed the antiapoptotic effect of insulin. Suggesting that the gene activity-dependent emergence of excitotoxicity contributed to insulin neurotoxicity, macromolecule synthesis inhibitors and N-methyl-D-aspartate (NMDA) antagonists blocked it. Consistently, exposure to insulin increased the level of the NR2A subunit of the NMDA receptor without much altering NR1 or NR2B levels. The present study suggests that insulin can be both neuroprotective and neurotoxic in the same cell system but by way of different signaling cascades. 相似文献
618.
N Hamada T Mimura A Suzuki J Noh J Takazawa T Iijima K Ito H Morii 《Endocrinologia japonica》1989,36(2):281-288
To investigate the role of parathyroid function in transient hypocalcemia after subtotal thyroidectomy for Graves' disease, the serum parathyroid hormone (PTH) concentration and nephrogenous (N) cAMP were measured in 16 patients before and after surgery. Serum PTH was measured with two commercially available kits (PTH-M, PTH-C), PTH-M is a recently developed highly sensitive assay using an antibody recognizing the mid-portion of human PTH and a synthetic 125I-tyr45-human PTH (43-68) as a radioligand. One of the 16 patients had severe clinical tetany and had a markedly lower PTH-M concentration and NcAMP after thyroidectomy. However, no significant change in serum PTH-M, PTH-C and NcAMP were observed in the other patients, although their serum calcium (Ca) concentrations decreased significantly. The Data were analyzed by dividing the patients according to the change in serum Ca or PTH. Serum PTH-M and PTH-C significantly decreased in 4 patients whose serum Ca clearly decreased after surgery. Serum Ca on the first postoperative day was significantly lower in patients whose serum PTH decreased after thyroidectomy than in patients whose serum PTH did not. Furthermore, the serum Ca concentration was significantly correlated with PTH-M, and with NcAMP on the third postoperative day. These data proved that hypofunction of the parathyroid gland is important in transient hypocalcemia after subtotal thyroidectomy for Graves' disease. The pathogenetic mechanism of transient hypocalcemia was discussed in comparison with the data from a patient who had overt parathyroid injury. 相似文献
619.
Nam Jin Noh Choonsig Kim Sang Won Bae Woo Kyun Lee Tae Kyung Yoon Hiroyuki Muraoka Yowhan Son 《Journal of Plant Ecology》2013,6(5):368
Aims Understanding carbon (C) and nitrogen (N) dynamics and their dependence on the stand density of an even-aged, mature forest provides knowledge that is important for forest management. This study investigated the differences in ecosystem total C and N storage and flux between a low-density stand (LD) and a high-density stand (HD) and examined the effects of stand density on aboveground net primary productivity (ANPP), total belowground C allocation (TBCA) and net ecosystem production (NEP) in a naturally regenerated, 65- to 75-year-old Pinus densiflora S. et Z. forest.Methods LD (450 trees ha-1) and HD (842 trees ha-1) were established in an even-aged, mature P. densiflora forest in September 2006. The forest had been naturally regenerated following harvesting, and the stand density was naturally maintained without any artificial management such as thinning. The diameter at breast height (DBH ≥ 5.0cm) of all live stems within the stands was measured yearly from 2007 to 2011. To compare C and N storage and fluxes in LD and HD, C and N pools in aboveground and belowground biomass, the forest floor, coarse woody debris (CWD) and soil; soil CO2 efflux (R S); autotrophic respiration (R A); litter production; and soil N availability were measured. Further, ANPP, TBCA and NEP were estimated from plot-based measurement data.Important findings Ecosystem C (Mg C ha-1) and N (Mg N ha-1) storage was, respectively, 173.0±7.3 (mean ± SE) and 4.69±0.30 for LD and 162±11.8 and 4.08±0.18 for HD. There were no significant differences in C and N storage in the ecosystem components, except for soils, between the two stands. In contrast, there were significant differences in aboveground ANPP and TBCA between the two stands (P < 0.05). Litterfall, biomass increment and R S were major C flux components with values of, respectively, 3.89, 3.74 and 9.07 Mg C ha-1 year-1 in LD and 3.15, 2.94 and 7.06 Mg C ha-1 year-1 in HD. Biometric-based NEP (Mg C ha-1 year-1) was 4.18 in LD and 5.50 in HD. Although the even-aged, mature P. densiflora forest had similar C and N allocation patterns, it showed different C and N dynamics depending on stand density. The results of the current study will be useful for elucidating the effects of stand density on C and N storage and fluxes, which are important issues in managing natural mature forest ecosystems. 相似文献
620.
Jong‐Ho Lee Hyoungchul Kim Sung Moon Kim Tae‐Wook Noh Hwa‐Young Jung Hyun‐Yup Lim Hun‐Gi Jung Ji‐Won Son Hae‐Ryoung Kim Byung‐Kook Kim Hae‐June Je Jae‐Chun Lee Huesup Song Hae‐Weon Lee 《Liver Transplantation》2012,2(4):461-468
Glass‐based seals for planar solid‐oxide fuel‐cell (SOFC) stacks are open to uncontrolled deformation and mechanical damages, limiting both sealing integrity and stack reliability, particularly in thermal cycle operations. If the glass‐based seals work like an elastomer‐based compressive seal, SOFC stacks may survive unprecedented numbers of thermal cycles. A novel composite sealing gasket is successfully developed to mimic the unique features of the elastomer‐based compressive seal by controlling the composition and packing behavior of binary ceramic fillers. A single‐cell SOFC stack undergoes more than 100 thermal cycles with little performance loss, during which the sealing integrity is lost/recovered repeatedly upon cooling and reheating, corresponding to unloading/loading of the elastomer‐based compressive seal. The thermal‐cycle responses of the SOFC stack are explained in sequence by the concurrent events of elastic deformation/recovery of ceramic filler network and corresponding redistribution of sealing glass. 相似文献