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41.
David L. G. Noakes 《Environmental Biology of Fishes》2008,81(1):1-5
The most recent in the continuing series of international conferences dedicated to charrs, Salvelinus species, was held in
Reykjavik, Iceland 1–5 August 2006. 相似文献
42.
Oxidation of exogenous carbohydrate during prolonged exercise: the effects of the carbohydrate type and its concentration. 总被引:1,自引:0,他引:1
D Moodley T D Noakes A N Bosch J A Hawley R Schall S C Dennis 《European journal of applied physiology and occupational physiology》1992,64(4):328-334
We studied rates of exogenous carbohydrate (CHO) oxidation during 90 min of cycling exercise in trained cyclists exercising at 70% of maximal oxygen consumption (VO2max) when they ingested glucose, sucrose, or glucose polymer solutions at concentrations of 7.5%, 10% or 15%. Drinks were labelled with [U-14C]glucose or sucrose and were ingested at a rate of 100 ml.10 min-1. Rates of oxidation of the ingested CHO were calculated from the specific radio-activity of the labelled CHO, expired 14CO2 and carbon dioxide output (VCO2). Total CHO oxidation, determined from oxygen consumption and VCO2 was not influenced by CHO type or concentration. Gastric emptying (P = 0.01) and the rate of exogenous CHO oxidation (P = 0.028) was greatest for the glucose polymer solutions, and least for glucose. Although gastric emptying (P = 0.006) decreased with increasing CHO concentration, CHO delivery to the intestine and exogenous CHO oxidation increased linearly with increasing CHO concentration. The percentage of the CHO delivered to the intestine that was oxidized ranged from 30.0% for 7.5% CHO to 38.1% for 15% CHO. Our results indicated that the rate of gastric emptying for CHO was not controlled to provide a constant rate of energy delivery as is commonly believed and that factors subsequent to gastric emptying limit the rate of exogenous CHO oxidation from the ingested solution. 相似文献
43.
van Gool CJ van Houwelingen AC Hornstra G 《The Journal of nutritional biochemistry》2000,11(11-12):543-547
Phenylketonuric patients are on a special diet that lacks certain essential fatty acids. This study evaluates the essential fatty acid status of a group of phenylketonuric patients in the Netherlands undergoing dietary treatment. To this end, the essential fatty acid status of nine phenylketonuria patients was studied. On the basis of age and gender, two control subjects were selected for each patient. The essential fatty acid composition of duplicate food portions and the essential fatty acid status of plasma and erythrocytes were analyzed. Phenylketonuria subjects had a different essential fatty acid profile from their peers, especially concerning the n-3 fatty acids. N-6 and n-3 fatty long-chain polyenes were hardly consumed by phenylketonuria subjects, in contrast to the control subjects. Linoleic acid, on the other hand, was consumed in significantly higher amounts by phenylketonuria subjects and made up about 40% of their daily fat consumption. The essential fatty acid consumption pattern of the phenylketonuria subjects is mirrored by the essential fatty acid concentrations in blood. The essential fatty acid status of the phenylketonuric diet should be improved in order to prevent deficiency in n-3 fatty acids. 相似文献
44.
Moira M. Ferguson David L. G. Noakes 《Ethology : formerly Zeitschrift fur Tierpsychologie》1983,62(1):72-86
Brook charr (Salvelinus fontinalis) defend territories and show high levels of agonistic behaviour. In contrast, lake charr (S. namaycush) are non-territorial and rarely show any agonistic behaviour. The genetic determinance of behavioural differences between these species was confirmed by the behavioural similarity of brook charr backcross hybrids and brook charr and a significant maternal effect on hybrid behavioural phenotypes. Backcross and F2 generations showed either one of two distinct behavioural strategies, one aggressive and territorial and the other non-aggressive and non-territorial. It seems most likely that these strategies are conditional on individual phenotypes, such as size of nearby conspecifics. However, precise measurements of costs and benefits of each strategy are required to distinguish between these alternate hypotheses for either species. Each action pattern was an independent pattern of variation and a distinct behavioural unit. However, patterns were coordinated with all other patterns at a higher hierarchical level (corresponding to the particular behavioural strategy). It seems most likely that these strategies would be controlled by a polygenic system, even though the nature of our data does not allow us to make firm conclusions in this regard. 相似文献
45.
Estelle V. Lambert David P. Speechly Steven C. Dennis Timothy D. Noakes 《European journal of applied physiology and occupational physiology》1994,69(4):287-293
These studies investigated the effects of 2 weeks of either a high-fat (HIGH-FAT: 70% fat, 7% CHO) or a high-carbohydrate (HIGH-CHO: 74% CHO, 12% fat) diet on exercise performance in trained cyclists (n = 5) during consecutive periods of cycle exercise including a Wingate test of muscle power, cycle exercise to exhaustion at 85% of peak power output [90% maximal oxygen uptake (
O2max), high-intensity exercise (HIE)] and 50% of peak power output [60%
O2max, moderate intensity exercise (MIE)]. Exercise time to exhaustion during HIE was not significantly different between trials: nor were the rates of muscle glycogen utilization during HIE different between trials, although starting muscle glycogen content was lower [68.1 (SEM 3.9) vs 120.6 (SEM 3.8) mmol · kg –1 wet mass, P < 0.01] after the HIGH-FAT diet. Despite a lower muscle glycogen content at the onset of MIE [32 (SEM 7) vs 73 (SEM 6) mmol · kg –1 wet mass, HIGH-FAT vs HIGH-CHO, P < 0.01], exercise time to exhaustion during subsequent MIE was significantly longer after the HIGH-FAT diet [79.7 (SEM 7.6) vs 42.5 (SEM 6.8) min, HIGH-FAT vs HIGH-CHO, P<0.01]. Enhanced endurance during MIE after the HIGH-FAT diet was associated with a lower respiratory exchange ratio [0.87 (SEM 0.03) vs 0.92 (SEM 0.02), P<0.05], and a decreased rate of carbohydrate oxidation [1.41 (SEM 0.70) vs 2.23 (SEM 0.40) g CHO · min–1, P<0.05]. These results would suggest that 2 weeks of adaptation to a high-fat diet would result in an enhanced resistance to fatigue and a significant sparing of endogenous carbohydrate during low to moderate intensity exercise in a relatively glycogen-depleted state and unimpaired performance during high intensity exercise. 相似文献
46.
Britten CJ; van den Eijnden DH; McDowell W; Kelly VA; Witham SJ; Edbrooke MR; Bird MI; de Vries T; Smithers N 《Glycobiology》1998,8(4):321-327
The alpha3 fucosyltransferase, FucT-VII, is one of the key
glycosyltransferases involved in the biosynthesis of the sialyl Lewis X
(sLex) antigen on human leukocytes. The sialyl Lewis X antigen
(NeuAcalpha(2-3)Galbeta(1-4)[Fucalpha(1-3)]GlcNAc-R) is an essential
component of the recruitment of leukocytes to sites of inflammation,
mediating the primary interaction between circulating leukocytes and
activated endothelium. In order to characterize the enzymatic properties of
the leukocyte alpha3 fucosyltransferase FucT-VII, the enzyme has been
expressed in Trichoplusia ni insect cells. The enzyme is capable of
synthesizing both sLexand sialyl-dimeric-Lexstructures in vitro , from
3'-sialyl-lacNAc and VIM-2 structures, respectively, with only low levels
of fucose transfer observed to neutral or 3'-sulfated acceptors. Studies
using fucosylated NeuAcalpha(2-3)-(Galbeta(1- 4)GlcNAc)3-Me acceptors
demonstrate that FucT-VII is able to synthesize both di-fucosylated and
tri-fucosylated structures from mono- fucosylated precursors, but
preferentially fucosylates the distal GlcNAc within a polylactosamine
chain. Furthermore, the rate of fucosylation of the internal GlcNAc
residues is reduced once fucose has been added to the distal GlcNAc. These
results indicate that FucT-VII is capable of generating complex selectin
ligands, in vitro , however the order of fucose addition to the lactosamine
chain affects the rate of selectin ligand synthesis.
相似文献
47.
J A Hawley S C Dennis B J Laidler A N Bosch T D Noakes F Brouns 《Journal of applied physiology》1991,71(5):1801-1806
This study compared the gastric emptying and oxidation of two 15% carbohydrate (CHO) solutions: a 22-chain-length glucose polymer (GP) and soluble starch (SS). Six endurance-trained subjects ingested 1,200 ml of either GP or SS while cycling for 90 min at 70% of maximal oxygen consumption (VO2max). Whereas the calculated total CHO oxidation (GP 266.8 +/- 41.9 g; SS 263.6 +/- 28.9 g) and the volume emptied from the stomach (GP 813 +/- 130 ml; SS 919 +/- 116 ml) were similar, the appearance of the 14C label in plasma occurred more rapidly from ingested SS than from GP (P less than 0.001). This resulted in a significantly greater rate of SS oxidation than that from GP (SS 105.9 +/- 21.9 g, GP 49.6 +/- 10.2 g; P less than 0.001). Exogenous CHO oxidation from GP accounted for 19% of total CHO oxidation, whereas the corresponding value for SS was 40%. This study suggests that the oxidation of SS and GP solutions ingested during exercise at 70% VO2max is not limited by gastric emptying. Rather, it appears to be either the rate of digestion or absorption of these solutions that determines their utilization. 相似文献
48.
The photobehaviour of young rainbow trout was studied from the time of hatching to completed emergence using an artificial turf substrate incubation system. At all light energies tested, free-embryos initiated a substantial downward movement and rates of fish descent did not appear to reflect the order of light energy levels. A nocturnal activity rhythm was established early in the downward phase. The occurrence of a rapid photoresponse shift 21 days after hatching coincided with the synchronous onset of emergence in all fish groups and the depletion of 85% (by volume) of the yolk reserve. Concurrent morphological observations indicated that the photoresponse change occurred when fish were about 25 mm long, and when paired and median fins were fully developed. 相似文献
49.
Paul Vecsei Matthew K. Litvak David L.G. Noakes Tom Rien Martin Hochleithner 《Environmental Biology of Fishes》2003,68(4):333-338
We have developed a noninvasive technique to determine the sex of adult North American sturgeon by examination of the external morphology of live individuals. We analyzed four sturgeon species taken by commercial and scientific harvest: white Acipenser transmontanus, green A. medirostris, Atlantic A. oxyrinchus and shortnose A. brevirostrum. Males have a urogenital opening in the shape of a letter Y, while the opening of females is in the shape of the letter O. We accurately sexed 26 of 36 sturgeon using this criterion. Accuracy was highest in live fish (82%), and significantly lower in dead fish (29%). Dead sturgeon usually have the rectum prolapsed so that the urogenital opening is protruded, and thus making the sexes indistinguishable. 相似文献
50.
To determine whether the reduced blood lactate concentrations [La] during submaximal exercise in humans after endurance training result from a decreased rate of lactate appearance (Ra) or an increased rate of lactate metabolic clearance (MCR), interrelationships among blood [La], lactate Ra, and lactate MCR were investigated in eight untrained men during progressive exercise before and after a 9-wk endurance training program. Radioisotope dilution measurements of L-[U-14C]lactate revealed that the slower rise in blood [La] with increasing O2 uptake (VO2) after training was due to a reduced lactate Ra at the lower work rates [VO2 less than 2.27 l/min, less than 60% maximum VO2 (VO2max); P less than 0.01]. At power outputs closer to maximum, peak lactate Ra values before (215 +/- 28 mumol.min-1.kg-1) and after training (244 +/- 12 mumol.min-1.kg-1) became similar. In contrast, submaximal (less than 75% VO2max) and peak lactate MCR values were higher after than before training (40 +/- 3 vs. 31 +/- 4 ml.min-1.kg-1, P less than 0.05). Thus the lower blood [La] values during exercise after training in this study were caused by a diminished lactate Ra at low absolute and relative work rates and an elevated MCR at higher absolute and all relative work rates during exercise. 相似文献