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排序方式: 共有874条查询结果,搜索用时 15 毫秒
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Jacobsen Kathryn H. Aguirre A. Alonso Bailey Charles L. Baranova Ancha V. Crooks Andrew T. Croitoru Arie Delamater Paul L. Gupta Jhumka Kehn-Hall Kylene Narayanan Aarthi Pierobon Mariaelena Rowan Katherine E. Schwebach J. Reid Seshaiyer Padmanabhan Sklarew Dann M. Stefanidis Anthony Agouris Peggy 《EcoHealth》2016,13(1):200-212
EcoHealth - As the Ebola outbreak in West Africa wanes, it is time for the international scientific community to reflect on how to improve the detection of and coordinated response to future... 相似文献
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Harini Narayanan Michael Sokolov Alessandro Butté Massimo Morbidelli 《Biotechnology progress》2019,35(4):e2818
This work presents a novel multivariate statistical algorithm, Decision Tree-PLS (DT-PLS), to improve the prediction and understanding of dynamic processes based on local partial least square regression (PLSR) models for characteristic process groups defined based on Decision Tree (DT) analysis. The DT-PLS algorithm is successfully applied to two different cell culture data sets, one obtained from bioreactors of 3.5 L lab scale and the other obtained from the 15 ml ambr microbioreactor system. Substantial improvement in the predictive capabilities of the model can be achieved based on the localization compared to the classical PLSR approach, which is implemented in the commercially available packages. Additionally, the differences in the model parameters of the local models suggest that the governing process variables vary for the different process regimes indicating the different states of the cell under different process conditions. 相似文献
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Margaret M. Jastreboff Etsuro Ito Joseph R. Bertino Ramaswamy Narayanan 《Experimental cell research》1987,171(2):513-517
Electroporation was used to introduce high-molecular-weight DNA into murine hematopoietic cells and NIH3T3 cells. CCRF-CEM cells were stably transfected with SV2NEO plasmid and the genomic DNA from G-418-resistant clones (greater than 65 kb) was introduced into mouse bone marrow and NIH3T3 cells by electroporation. NEO sequences and expression were detected in the hematopoietic tissues of lethally irradiated mice, with 24% of individual spleen colonies expressing NEO. The frequency of genomic DNA transfer into NIH3T3 cells was 0.25 X 10(-3). Electroporation thus offers a powerful mode of gene transfer not only of cloned genes but also of high-molecular-weight DNA into cells. 相似文献
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Gilda Grard Joseph N. Fair Deanna Lee Elizabeth Slikas Imke Steffen Jean-Jacques Muyembe Taylor Sittler Narayanan Veeraraghavan J. Graham Ruby Chunlin Wang Maria Makuwa Prime Mulembakani Robert B. Tesh Jonna Mazet Anne W. Rimoin Travis Taylor Bradley S. Schneider Graham Simmons Eric Delwart Nathan D. Wolfe Charles Y. Chiu Eric M. Leroy 《PLoS pathogens》2016,12(3)