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101.
Nilesh Kumar Pathak Nikhil Chander Vamsi K. Komarala R. P. Sharma 《Plasmonics (Norwell, Mass.)》2017,12(2):237-244
The role of Au@SiO2 core-shell nanoparticles on optical properties of perovskite solar cells has been explored using both the theoretical computations and the experiments. A quasi-static model is used to study the surface plasmon resonances (SPRs) of Au@SiO2 core-shell nanospheres. Au@SiO2 core-shell nanoparticles, with varying shell thickness and core radius, were assumed to be embedded in methylammonium lead triiodide (CH3NH3PbI3) perovskite active layer. Enhanced absorption in the active layer is obtained due to the near-field plasmonic effect of the embedded core-shell nanoparticles. Theoretical modelling shows that a shell thickness of 1 nm and core diameter of 20 nm provide absorption enhancement in the orange-red region of the electromagnetic spectrum. Experiments performed using ~20-nm-sized Au@SiO2 core-shell nanoparticles (with a shell thickness of ~1 nm) clearly demonstrate the enhanced absorption and the resulting enhancement in photocurrent due to the plasmonic effects. An efficiency enhancement of over 18 % is obtained for the best plasmonic perovskite solar cell containing Au@SiO2 nanoparticles in Au@SiO2-TiO2 weight ratio of ~1 %. Incident photon-to-current conversion efficiency (IPCE) data also showed enhancement in photocurrent for the plasmonic device. The quasi-static modelling approach provides a good correlation between theory and experiment. 相似文献
102.
Bhardwaj Shivani Pathak Nilesh Kumar Ji Alok Uma R. Sharma R. P. 《Plasmonics (Norwell, Mass.)》2017,12(1):193-201
Plasmonics - Graphene plasmonic resonances play a significant role for enhancing the photon absorption inside thin film solar devices. We investigate the field rising at the intersection of... 相似文献
103.
Pankaj Thapa Nilesh Shanmugam Wojciech Pokrzywa 《BioEssays : news and reviews in molecular, cellular and developmental biology》2020,42(1):1900171
The fate of eukaryotic proteins, from their synthesis to destruction, is supervised by the ubiquitin–proteasome system (UPS). The UPS is the primary pathway responsible for selective proteolysis of intracellular proteins, which is guided by covalent attachment of ubiquitin to target proteins by E1 (activating), E2 (conjugating), and E3 (ligating) enzymes in a process known as ubiquitylation. The UPS can also regulate protein synthesis by influencing multiple steps of RNA (ribonucleic acid) metabolism. Here, recent publications concerning the interplay between the UPS and different types of RNA are reviewed. This interplay mainly involves specific RNA-binding E3 ligases that link RNA-dependent processes with protein ubiquitylation. The emerging understanding of their modes of RNA binding, their RNA targets, and their molecular and cellular functions are primarily focused on. It is discussed how the UPS adapted to interact with different types of RNA and how RNA molecules influence the ubiquitin signaling components. 相似文献
104.
Pandey Gyanendra Krishna Pathak Nilesh Kumar Uma R. Sharma R. P. 《Plasmonics (Norwell, Mass.)》2018,13(1):221-229
Plasmonics - In this communication, we study the surface enhanced Raman scattering (SERS) by a molecule which is adsorbed on a trilayer (Ag@SiO2@Ag) spherical shaped metallic nanostructure. We have... 相似文献
105.
Plasmonics - In the present work, an investigation of wavelength-dependent absorption spectrum of spherical nanoparticles with different arrangements in organic medium using discrete dipole... 相似文献
106.
Payal Singh Nilesh Kumar Minesh Jethva Saurabh Yadav Pragati Kumari Archana Thakur Hemant Ritturaj Kushwaha 《Physiology and Molecular Biology of Plants》2018,24(2):315-324
Cyanobacteria are one of the ancient bacterial species occupying a variety of habitats with diverse metabolic preferences. RNA regulators like riboswitches play significant role in controlling the gene expression in prokaryotes. The taxonomic distribution of riboswitches suggests that they might be one of the oldest mechanisms of gene control system. In this paper, we analyzed the distribution of different riboswitch families in various cyanobacterial genomes. It was observed that only four riboswitch classes were abundant in cyanobacteria, B12-element (Cob)/AdoCbl/AdoCbl-variant riboswitch being the most abundant. The analysis suggests that riboswitch mode of regulation is present in cyanobacterial species irrespective of their habitat types. A large number of unidentified genes regulated by riboswitches listed in this analysis indicate the wide range of targets for these riboswitch families. The analysis revealed a large number of genes regulated by riboswitches which may assist in elaborating the diversity among the cyanobacterial species. 相似文献
107.
Radoslaw Debiec Paraskevi Christofidou Matthew Denniff Lisa D. Bloomer Pawel Bogdanski Lukasz Wojnar Katarzyna Musialik Fadi J. Charchar John R. Thompson Dawn Waterworth Kijoung Song Peter Vollenweider Gerard Waeber Ewa Zukowska-Szczechowska Nilesh J. Samani David Lambert Maciej Tomaszewski 《PloS one》2013,8(12)
Urotensin-II controls ion/water homeostasis in fish and vascular tone in rodents. We hypothesised that common genetic variants in urotensin-II pathway genes are associated with human blood pressure or renal function. We performed family-based analysis of association between blood pressure, glomerular filtration and genes of the urotensin-II pathway (urotensin-II, urotensin-II related peptide, urotensin-II receptor) saturated with 28 tagging single nucleotide polymorphisms in 2024 individuals from 520 families; followed by an independent replication in 420 families and 7545 unrelated subjects. The expression studies of the urotensin-II pathway were carried out in 97 human kidneys. Phylogenetic evolutionary analysis was conducted in 17 vertebrate species. One single nucleotide polymorphism (rs531485 in urotensin-II gene) was associated with adjusted estimated glomerular filtration rate in the discovery cohort (p = 0.0005). It showed no association with estimated glomerular filtration rate in the combined replication resource of 8724 subjects from 6 populations. Expression of urotensin-II and its receptor showed strong linear correlation (r = 0.86, p<0.0001). There was no difference in renal expression of urotensin-II system between hypertensive and normotensive subjects. Evolutionary analysis revealed accumulation of mutations in urotensin-II since the divergence of primates and weaker conservation of urotensin-II receptor in primates than in lower vertebrates. Our data suggest that urotensin-II system genes are unlikely to play a major role in genetic control of human blood pressure or renal function. The signatures of evolutionary forces acting on urotensin-II system indicate that it may have evolved towards loss of function since the divergence of primates. 相似文献
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110.
Vasa-Nicotera M Brouilette S Mangino M Thompson JR Braund P Clemitson JR Mason A Bodycote CL Raleigh SM Louis E Samani NJ 《American journal of human genetics》2005,76(1):147-151
Telomere length is a crucial factor for both normal chromosomal function and senescence. Mean telomere length in humans shows considerable interindividual variation and strong genetic determination. To see if a locus (or loci) affecting telomere length in humans could be mapped, we performed a quantitative-trait linkage analysis of mean leukocyte telomere-restriction-fragment (TRF) lengths, measured by Southern blotting, in 383 adult subjects comprising 258 sib pairs. Heritability of mean (+/-SE) TRF was 81.9%+/-11.8%. There was significant linkage (LOD score 3.20) of mean TRF length to a locus on chromosome 12, which explained 49% of the overall variability in mean TRF length. We present preliminary analysis of a strong candidate gene in the region, the DNA helicase DDX11. In conclusion, we report mapping of the first locus that determines mean telomere length in humans. Identification of the gene involved and elucidation of its mechanism of action could have important implications for our understanding of chromosomal assembly, telomere biology, and susceptibility to age-related diseases. 相似文献