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van der Zijden AM Groen BE Tanck E Nienhuis B Verdonschot N Weerdesteyn V 《Journal of biomechanics》2012,45(9):1650-1655
Sideways falls onto the hip are a major cause of femoral fractures in the elderly. Martial arts (MA) fall techniques decrease hip impact forces in sideways falls. The femoral fracture risk, however, also depends on the femoral loading configuration (direction and point of application of the force). The purpose of this study was to determine the effect of fall techniques, landing surface and fall height on the impact force and the loading configuration in sideways falls. Twelve experienced judokas performed sideways MA and Block ('natural') falls on a force plate, both with and without a judo mat on top. Kinematic and force data were analysed to determine the hip impact force and the loading configuration. In falls from a kneeling position, the MA technique reduced the impact force by 27%, but did not change the loading configuration. The use of the mat did not change the loading configuration. Falling from a standing changed the force direction. In all conditions, the point of application was distal and posterior to the greater trochanter, but it was less distal and more posterior in falls from standing than from kneeling position. The present decrease in hip impact force with an unchanged loading configuration indicates the potential protective effect of the MA technique on the femoral fracture risk. The change in loading configuration with an increased fall height warrant further studies to examine the effect of MA techniques on fall severity under more natural fall circumstances. 相似文献
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Nienhuis HL de Leeuw K Bijzet J van Doormaal JJ van Roon AM Smit AJ Graaff R Kallenberg CG Bijl M 《Arthritis research & therapy》2010,12(5):R181
Introduction
The objectives of this study were to determine small arterial elasticity (SAE) in systemic lupus erythematosus (SLE) and to investigate its relationship with intima media thickness (IMT), accumulation of advanced glycation end products (AGEs), endothelial activation and inflammation. 相似文献36.
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Somatic cell hybrids exhibiting co-expression of the globin genes of two species were generated by fusion of mouse erythroleukemia cells with Chinese hamster or human marrow erythroid cells. In contrast, extinction of the mouse globin genes occurred in hybrids formed between the erythroleukemia cells and human fibroblasts. Direct detection of the human globin genes in human X mouse fibroblast hybrids was achieved by annealing of DNA from these cells to human globin complementary DNA. This method was developed to permit the chromosomal assignment of the human globin genes. 相似文献
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Albert Deisseroth Arthur Nienhuis 《In vitro cellular & developmental biology. Plant》1976,12(11):734-742
Summary Somatic cell hybrids exhibiting co-expression of the globin genes of two species were generated by fusion of mouse erythroleukemia
cells with Chinese hamster or human marrow erythroid cells. In contrast, extinction of the mouse globin genes occurred in
hybrids formed between the erythroleukemia cells and human fibroblasts. Direct detection of the human globin genes in human
X mouse fibroblast hybrids was achieved by annealing of DNA from these cells to human globin complementary DNA. This method
was developed to permit the chromosomal assignment of the human globin genes.
Presented in the formal symposium on Somatic Cell Genetics at the 27th Annual Meeting of the Tissue Culture Association, Philadelphia,
Pennsylvania, June 7–10, 1976.
Some of this work was conducted during the tenure of a National Research Fellowship 1 F32 AM05080-01 held by A.D. 相似文献
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