全文获取类型
收费全文 | 234篇 |
免费 | 12篇 |
出版年
2023年 | 4篇 |
2022年 | 6篇 |
2021年 | 14篇 |
2020年 | 14篇 |
2019年 | 7篇 |
2018年 | 12篇 |
2017年 | 15篇 |
2016年 | 12篇 |
2015年 | 12篇 |
2014年 | 14篇 |
2013年 | 17篇 |
2012年 | 15篇 |
2011年 | 19篇 |
2010年 | 12篇 |
2009年 | 8篇 |
2008年 | 9篇 |
2007年 | 6篇 |
2006年 | 4篇 |
2005年 | 1篇 |
2004年 | 4篇 |
2003年 | 5篇 |
2002年 | 4篇 |
2001年 | 1篇 |
1998年 | 1篇 |
1997年 | 3篇 |
1995年 | 1篇 |
1994年 | 1篇 |
1993年 | 1篇 |
1992年 | 2篇 |
1991年 | 3篇 |
1990年 | 3篇 |
1989年 | 3篇 |
1988年 | 1篇 |
1986年 | 7篇 |
1985年 | 3篇 |
1984年 | 1篇 |
1980年 | 1篇 |
排序方式: 共有246条查询结果,搜索用时 187 毫秒
241.
Ghosh Mounita Akhter Nasrin Zobayer Nayem 《International journal of peptide research and therapeutics》2021,27(3):2111-2124
International Journal of Peptide Research and Therapeutics - The osteoclast is a kind of bone cell that splits down the bone tissue. The osteoclast is responsible for bone disease. So, the... 相似文献
242.
Mitra Zarebavani Farinaz Baghaei Naeini Amirali Farahvash Fatemeh Moradi Nasrin Dashti 《Journal of biochemical and molecular toxicology》2023,37(5):e23311
Social isolation stress (SIS) is associated with affective disorders (i.e., anxiety and depression) in adults. In a preclinical study, we aimed to investigate the effects of resveratrol (RV) on the mood swings of rats exposed to SIS. Animals were randomized into six different groups, including control: healthy animals received normal saline (NS) as a vehicle; SIS + NS: SIS animals received NS; SIS + FL: SIS animals received fluoxetine (10 mg/kg/i.p.); SIS + RV20, SIS + RV40, and SIS + RV80: SIS animals received RV (20, 40, and 80 mg/kg/i.p). SIS was induced for 4 weeks, then animals were treated with NS, FL, and RV for 4 weeks. Rats were evaluated by the behavioral tests, including the elevated plus-maze, tail suspension test, the open field test, and forced-swimming test, for mood alterations and nuclear factor kappa B (NF-κB) levels, along with NLRP3, apoptosis-associated speck-like (ASC), and proCaspase-1 were determined in the hippocampus. Behavioral tests confirmed that exposing the animals to SIS caused anxiety and depression. The highest concentrations of NLRP3, proCaspase-1, ASC, and NF-κB, were confirmed in the SIS + NS group. Compared to FL, RV showed antidepressant potential according to the behavioral tests. In particular, the administration of RV (20, 40, and 80 mg/kg) revered the NF-κB/NLRP3 axis cascade in rats exposed to chronic SIS. Our findings revealed that RV attenuated anxiety and depression of SIS-exposed rats via regulation of NF-κB/NLRP3 signaling pathways. RV can be used as a potential anxiolytic agent and antidepressant. 相似文献
243.
Kamali Amir Hossein Giannoulatou Eleni Chen Tsong Yueh Charleston Michael A. McEwan Alistair L. Ho Joshua W. K. 《Biophysical reviews》2015,7(3):343-352
Biophysical Reviews - Bioinformatics is the application of computational, mathematical and statistical techniques to solve problems in biology and medicine. Bioinformatics programs developed for... 相似文献
244.
245.
Congenital malformations and genetic diseases in Iranian infants 总被引:1,自引:0,他引:1
Summary Data of 13,037 live-born infants from a hospital in Tehran, Iran were analysed for congenital malformations and genetic diseases. The results showed that the rates of joint dislocation, eleft lip, cleft palate and finger anomalies are similar to those of the other populations. The rates of chromosomal, thorax and abdominal, external genital anomalies and other syndromes were higher compared with other populations, whereas the rates of multiple births and limb anomalies were lower. 相似文献
246.
S.A. Mohammadi M. Khodarahmi S. Jamalirad & M.R. Jalal Kamali 《The Annals of applied biology》2009,154(1):67-76
Genetic diversity in a collection of 70 bread wheat ( Triticum aestivum ) genotypes was studied using 73 microsatellite [simple sequence repeat (SSR)] loci evenly spaced on wheat chromosomes. A total of 592 alleles with an average of 8.53 allele/locus were detected, of which 185 (31.25%) occurred only in a specific group of genotypes. A set of SSR markers consisted of 22 loci with polymorphic information content values of 0.80 or higher were selected for rapid fingerprinting of many genotypes. Average of gene diversity was 0.74 ± 0.017, and significant difference between observed and maximum theoretical values of gene diversity in the analysed SSR loci was obtained using a paired t -test. Genetic distance-based clustering methods including unweighted pair group method with arithmetic average and neighbour joining (NJ) were used for grouping of genotypes. The resulted dendrogram based on NJ and number of differences coefficient hinted of the existence of three groups. This grouping was in agreement with the pedigree information and confirmed by high within-group bootstrap value. A comparatively higher genetic diversity in the studied wheat collection as revealed by presence of high allelic diversity and large number of specific alleles could be utilised in development of new cultivars with desired characteristics. 相似文献