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Stat3 Controls Cell Movements during Zebrafish Gastrulation 总被引:6,自引:0,他引:6
Yamashita S Miyagi C Carmany-Rampey A Shimizu T Fujii R Schier AF Hirano T 《Developmental cell》2002,2(3):363-375
995.
We have previously reported that resistance exercise improved the iron status in iron-deficient rats. The current study investigated the mechanisms underlying this exercise-related effect. Male 4-week-old rats were divided into a group sacrificed at the start (week 0) (n?=?7), a group maintained sedentary for 6 weeks (S) or a group that performed exercise for 6 weeks (E), and all rats in the latter groups were fed an iron-deficient diet (12 mg iron/kg) for 6 weeks. The rats in the E group performed climbing exercise (5 min?×?6 sets/day, 3 days/week). Compared to the week 0 rats, the rats in the S and E groups showed lower tissue iron content, and the hematocrit, hemoglobin, plasma iron, and transferrin saturation values were all low. However, the tissue iron content and blood iron status parameters, and the whole body iron content measured using the whole body homogenates of the rats, did not differ between the S group and the E group. The messenger RNA (mRNA) expression levels of hepcidin, duodenal cytochrome b, divalent metal transporter 1, and ferroportin 1 did not differ between the S group and the E group. The apparent absorption of iron was significantly lower in the E group than in the S group. Therefore, it was concluded that resistance exercise decreases iron absorption, whereas the whole body iron content is not affected, and an increase in iron recycling in the body seems to be responsible for this effect. 相似文献
996.
Community processes are now undergoing substantial reconfiguration because of climate change. Although the effects of climate change on ecosystems are currently a major concern, the issues tightly associated with winter climate change have been underrepresented. Given the importance of winter climate variables and events for determining the spatial distribution of communities and their phenological and physiological responses, and the functional roles of each species, all of which are expected to substantially influence community dis/re-assemble in the future, this review focuses on the ecological responses and consequences of terrestrial communities to changing winter climate. In particular, the effects on processes supported by biological interactions are largely undetermined. In this context, focusing on plant–soil feedback as a major interactive multi-system is worthwhile; these interactions can be disentangled through careful evaluation of the functional roles of organisms involved in the feedback (i.e., plants and soil organisms). The underlying mechanisms are indeed complex because direct (i.e., changes in physical conditions) and indirect pathways (i.e., plant-mediated influences on soil-organisms and vice versa) from winter climate change influence the functionality of future ecosystems. To face these issues, the framework of response–effect-traits deserves research priority since this can define community re-organization as the accumulated responses of individual species, which determines the stability and performance of ecosystem functioning. Thus, research that quantifies functional responses and roles of organisms under a changing climate will continue to be essential for the issues of winter climate change, which may become more serious and significant in the near future. 相似文献
997.
Our aim was to design a simple compression system and investigate the influence of mechanical stress on skin-like structures. Many mechanical compression studies have employed intricate culture systems, so the relationship between extracellular matrix material and the response of skin cells to mechanical stress remains unknown. Our approach uses only glass vials, 6-well plates and standard laboratory equipment. We examined the influence of mechanical stress on human skin fibroblasts embedded within a collagen sponge. The results show that mechanical compression increases MMP-1 and MMP-2 release by the cells into the the cell culture. Our results suggest that pressure on the skin may affect extracellular matrix degradation through some as yet unidentified pathways and that IL-6 mRNA expression may be involved in this effect. Using our approach, the effects of static mechanical stress on protein expression by cells in the culture medium and in sponges can be easily examined, and therefore this system will be useful for further analyses of skin responses to mechanical stress. 相似文献
998.
Salem Djedidi Katsuhiro Kojima Hiroko Yamaya Naoko Ohkama-Ohtsu Sonoko Dorothea Bellingrath-Kimura Izumi Watanabe Tadashi Yokoyama 《Journal of plant research》2014,127(5):585-597
The effects of inoculation with Bacillus and Azospirillum strains on growth and cesium accumulation of five plant species, Komatsuna, Amaranth, sorghum, common millet and buckwheat, grown on cesium-spiked soil were assessed for potential use in cesium remediation. Pot experiments were performed using “artificially” Cs-contaminated soil. Three treatments were applied based on Cs location in the soil. For a soil height of 15 cm in the pots, Cs was added as follows: in the top five cm to imitate no ploughing condition; in the bottom five cm simulating inverted ploughing; and uniformly distributed Cs reproducing normal plowing. Generally, inoculation of Cs-exposed plants significantly enhanced growth and tolerance to this element. Transfer factor (ratio of Cs concentration in the plant tissues to that in surrounding soil) was strongly influenced by Cs distribution, with higher values in the top-Cs treatment. Within this treatment, inoculation of Komatsuna with Bacillus and Azospirillum strains resulted in the greatest transfer factors of 6.55 and 6.68, respectively. Cesium content in the shoots was high in the Azospirillum-inoculated Komatsuna, Amaranth, and buckwheat, i.e., 1,830, 1,220, and 1,030 µg per pot, respectively (five plants were grown in each pot). Therefore, inoculation of Komatsuna and Amaranth with the strains tested here could be effective in enhancing Cs accumulation. The decrease of Cs transfer under uniform- and bottom-Cs treatments would suggest that countermeasures aiming at decreasing the transfer of Cs could rely on ploughing practices. 相似文献
999.
Fumiko Ishihama Shinji Fujii Kazuhiko Yamamoto Takenori Takada 《Population Ecology》2014,56(2):275-288
Mortality, a critical parameter for population dynamics, is difficult to measure in long-lived trees or clonal herbaceous species because of the extremely low frequency of deaths. A model based on shoot recruitment would be helpful to estimate the population fate of species without a sufficient number of observed deaths. Existing matrix models are applicable to the dynamics of physiologically independent shoots, but not to physiologically dependent ones. We developed a shoot-dynamics model for plants with physiologically-dependent shoots, and used the model to estimate the effects of herbivory and conservation measures on the dynamics of a long-lived, shoot-sprouting shrub species, Paliurus ramosissimus (Rhamnaceae). Two populations of the endangered shrub have been severely damaged by herbivory by sika deer. The damage was mainly to new sprouting shoots. No deaths of individual plants were observed during an 8-year survey, and we could not estimate mortality. Thus, prediction of population dynamics based on births and deaths of individuals was impossible. Because P. ramosissimus is a shoot-sprouting species, we instead estimated the decline of individuals using a shoot-dynamics model. Using this model, we estimated the time to an 80 % decrease in shoot number per individual in the two populations at 37.8 and 37.2 years. These lengths suggest an immediate need for conservation measures to prevent herbivory even though no death of any individual was observed in the field survey. The estimated recovery times from the herbivory damage were 28.7 and 29.2 years if herbivory of new shoots is completely prevented by conservation measure. 相似文献
1000.
Goro Tanifuji Naoko T Onodera Matthew W Brown Bruce A Curtis Andrew J Roger Gane Ka-Shu Wong Michael Melkonian John M Archibald 《BMC genomics》2014,15(1)