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991.
A new limonoid, 7-acetyltrichilin A, has been isolated from the root bark of Trichilia roka and identified as an antifeedant against North American and Japanese pest insects. 相似文献
992.
Radioactive tracer work showed that [14C]nomilin was converted to at least four metabolites in Citrus limon. One metabolite was identified as obacunone, showing that obacunone is biosynthesized from nomilin in C. limon. 相似文献
993.
Thirteen new labdane-type diterpenes have been isolated from the seeds of Sciadopitys verticillata together with six known ones, sciadin, sciadinone, dimethyl sciadinonate, lambertianic acid and its methyl ester and trans-communic acid. Their structures have been determined by chemical and spectral methods. 相似文献
994.
Growth (assessed from intermolt period and molt increment) andmetabolism (oxygen consumption) of juvenile and adult Thysanoessalongipes from central Japan Sea were determined at eight differenttemperatures ranging from 0 to 14°C. The intermolt periodshortened progressively as temperature increased from 0 to 14°C.The molt increment was not assessed satisfactorily in the rearingexperiments, and therefore this was estimated from the naturalgrowth curve and habitat temperature, combined with laboratory-obtainedintermolt data. Oxygen consumption rates increased exponentiallyfrom 0 to 8°C and then leveled off. From these results,the growth was expressed as a function of temperature and bodysize and metabolism as a function of temperature. Because ofthe differential effects of temperature on growth and metabolism,the net growth efficiency [NGE: 100 x growth/(growth + metabolism)]changed with temperature. The temperature at which T. longipesattained maximum NGE varied from 0 to 8°C, depending onthe body length of specimens of 5, 10, 15 and 20 mm. The presentresults are compared with our previous data on Euphausia pacificain relation to the body composition and habitat usage of thesetwo trophically important species in the food web of the JapanSea. 相似文献
995.
K. Tanaka Akira Yamada Kiyoshi Noda Takashi Hasegawa Masao Okuda Yukihiro Shoyama Kikuo Nomoto 《Cancer immunology, immunotherapy : CII》1998,45(6):313-320
A glycoprotein extract (CVS), derived from the unicellular green alga Chlorella vulgaris, strain CK22, exhibited a pronounced antitumor effect against both spontaneous and experimentally induced metastasis in mice.
Inhibition of tumor metastasis was enhanced when intratumor administration of CVS was followed by s.c. injection of CVS. Anti-metastatic
immunopotentiation was observed in euthymic mice, but not in athymic nude mice. The antitumor activity of CVS was reflected
in antigen-specific, T-cell-mediated immunity. Both CD4 and CD8 T cells contributed to the antimetastatic effects, as shown
by in vivo depletion experiments with anti-T-cell subset antibodies. Furthermore, CVS caused the recruitment of T cells to
the regional lymph nodes and their proliferation in these organs. The CD4-positive population, following CVS injection at
the time of tumor rechallenge, displayed a pronounced increase in the proportion of T cells that were CD18 bright, CD44 bright,
CD25+, CD54+, CD69+ or CD71+ in the lymph nodes. Thus, CVS induces T cell activation in peripheral lymph nodes in tumor-bearing mice. We conclude that
CVS augments antimetastatic immunity through T cell activation in lymphoid organs and enhances recruitment of these cells
to the tumor sites. Presurgical treatment with CVS might prevent metastasis or tumor progression.
Received: 5 June 1997 / Accepted: 12 September 1997 相似文献
996.
Yoshitsugu Iinuma Satoshi Ichiyama Sadaaki Yamori Jinya Oohama Norio Takagi Yoshinori Hasegawa Kaoru Shimokata Nobuo Nakashima 《Microbiology and immunology》1998,42(4):281-287
We evaluated the Amplicor PCR assay as an initial diagnostic tool on the basis of clinical diagnosis, and assessed this assay as a follow-up test for patients with pulmonary tuberculosis during chemotherapy. Of the 208 specimens from 155 patients who were bacteriologically and/or clinically diagnosed with active tuberculosis before chemotherapy, 144 were Amplicor PCR-positive (sensitivity, 69.2%), which was equal to the results of culturing. Among 89 specimens which showed positive results by smear and culturing, the Amplicor PCR assay detected 87 (97.8%), whereas among 55 specimens which showed smear-negative but culture-positive results, the Amplicor PCR assay detected 46 (83.6%)(P = 0.003). No false positive results were found in the two systems (specificity, 100%, 120/120). The Amplicor PCR assay was also evaluated as a follow-up test using 926 specimens from 207 patients receiving active tuberculosis chemotherapy. Among 433 specimens which showed Amplicor-PCR positive, 222 (51.3%) were culture-negative. On the other hand, among 233 culture-positive specimens, only 12 (5.2%) were Amplicor PCR-negative. Therefore, this assay is useful for the rapid diagnosis of tuberculosis. The duration of Amplicor PCR-positive after culture-negative conversion was significantly associated with the presence of cavitary lesion, smear-positive specimens before treatment, and smear-positive specimens with negative cultures during chemotherapy. 相似文献
997.
998.
Summary A sporadic translocation between two homologues of chromosome 15 was identified, by means of the quinacrine mustard fluorescence technique, in a phenotypically normal female infant with ventricular septal defect. Familial studies revealed certain individual variations regarding the intensely fluorescent centromeric regions in chromosomes 3 and 13, which appeared to be transmitted from the parents to offspring.
Contributions from the Chromosome Research Unit, Faculty of Science, Hokkaido University, Sapporo, Japan. Supported by grants, No. 584099, and No. 92035, from the Scientific Research Fund of the Ministry of Education. 相似文献
Zusammenfassung Eine sporadische Translokation zwischen zwei homologen Chromosomen Nr. 15 wurde mit Hilfe der Quinacrine-Mustard-Fluorescenztechnik bei einem weiblichen Säugling mit Ventrikelseptumdefekt festgestellt, der sonst phänotypisch normal war. Familienuntersuchungen ergaben gewisse individuelle Varianten der Zentromerregion in den Chromosomen 3 und 13, und es wurde eine Vererbung von den Eltern auf ihre Kinder festgestellt.Familienberatungen ergaben gewisse individuelle Variationen der intensiv fluorescierenden Zentromerregion.
Contributions from the Chromosome Research Unit, Faculty of Science, Hokkaido University, Sapporo, Japan. Supported by grants, No. 584099, and No. 92035, from the Scientific Research Fund of the Ministry of Education. 相似文献
999.
1000.
Naoki Koyama 《Primates; journal of primatology》1973,14(2-3):225-244
Social relationships, including dominance, grooming, and clasped-sleeping, were studied in a troop of bonnet monkeys (Macaca radiata) at Dharwar, India, the study period lasting two months and a half. Three measurements, the peanut test, the drinking test, and the spatial distribution test, were used to analyze dominance relationships. The peanut test showed a straight linear ranking order among adult males and females; however, among females drinking and spatial distribution orders are slightly different from that of feeding (peanut test). Grooming was observed more frequently between adult female and adult female and was seldom observed between adult male and juvenile female or between juvenile male and juvenile female. Apparently all monkeys tend to groom with females. On the other hand, monkeys of the same sex tend to sleep with each other. It is clear that monkeys select their partners when they groom and sleep. 相似文献