The role of low molecular weight proteins in exposure of blood to laser radiation and varying magnetic field

In this work we studied variations of oxygen-binding capacity of hemoglobin under the separate and joint action of a nanointegrator—a special device that provides a low-intensity laser radiation (LILR, 655 nm)—and an alternating magnetic field (AMF) on blood (erythrocytes and plasma) in the presence of low molecular weight proteins (LWP). The action of LILR and AMF is demonstrated to increase oxygen absorption by 50% and, in the presence of LWP, by 80–100%. LILR reduces the activity of a blood enzyme superoxide dismutase (SOD) by 60% and, in the presence of LWP, by 40%. The joint action of LILR and AMF first stimulates and, after 30 min, inhibits SOD activity. It is shown that LILR and AMF action not only changes the anti-oxidant status of blood, but also promotes oxygen uptake by erythrocytes. The effect of radiation is enhanced due to nanomolecular changes in LWP structure that boost the absorption of oxygen by cells.