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991.
992.
P Couillin R Mollicone M C Grisard A Gibaud N Ravisé J Feingold R Oriol 《Cytogenetics and cell genetics》1991,56(2):108-111
Seventy-one human x mouse hybrid cell lines were used to map the locus of a human alpha-3-fucosyltransferase to 11q. The enzyme transfers fucose onto H type 2 more efficiently than onto sialyl-N-acetyllactosamine, suggesting that it is the myeloid type of alpha-3-fucosyltransferase (Mollicone et al., 1990), which makes the 3-fucosyllactosamine epitope on polymorphonuclear cells and monocytes. This epitope is also known as CD15 (Tetteroo et al., 1987). 相似文献
993.
I. Albesa P. Bogdanov A. Eraso N.R. Sperandeo M.M. de Bertorello 《Journal of applied microbiology》1995,78(4):373-377
I. ALBESA, P. BOGDANOV, A. ERASO, N.R. SPERANDEO AND M.M. DE BERTORELLO. 1995. The antibiotic activity of new synthetic isoxazolylnaphthoquinone imines was studied. Pseudomonas aeruginosa ATCC 27853 and Escherichia coli ATCC 25922 were resistant to the four compounds studied (MIC > 128 µg ml−1 ), but Staphylococcus aureus ATCC 25923, ATCC 29213 and 30 clinical isolates of Staph. aureus were inhibited by 2-hydroxy- N -(3,4-dimethyl-5-isoxazolyl)-1,4-naphthoquinone-4-imine (I). This compound diminished bloodstream infection of mice injected i.m. with Staph. aureus; septicaemia decayed significantly when I was applied at the beginning of the infection while when I was given 3 d after bacterial challenge, a significant protection was afforded. Bactericidal activity in serum increased during the 5 h after I was administered i.p.
The acetyl derivative of I had a high MIC but when inoculated orally in mice decreased the Staph. aureus counts in circulation. This protection occurred only when the schedule of administration started close to the bacterial challenge. Antibiotic activity in vivo may be associated with in vitro effects. 相似文献
The acetyl derivative of I had a high MIC but when inoculated orally in mice decreased the Staph. aureus counts in circulation. This protection occurred only when the schedule of administration started close to the bacterial challenge. Antibiotic activity in vivo may be associated with in vitro effects. 相似文献
994.
995.
N Brinkmann M Malissard M Ramuz U R?mer T Schumacher E G Berger L Elling C Wandrey A Liese 《Bioorganic & medicinal chemistry letters》2001,11(18):2503-2506
The alpha-Gal trisaccharide Gal(alpha)(1-->3)Galbeta(1-->4)GlcNAc 11 was synthesized on a homogeneously soluble polymeric support (polyethylene glycol, PEG) by use of a multi-enzyme system consisting of beta-1,4-galactosyltransferase (EC 2.4.1.38), alpha-1,3-galactosyltransferase (EC 2.4.1.151), sucrose synthase (EC 2.4.1.13) and UDP-glucose-4-epimerase (EC 5.1.3.2). In addition workup was simplified by use of dia-ultrafiltration. Thus the advantages of classic chemistry/enzymology and solid-phase synthesis could be united in one. Subsequent hydrogenolytic cleavage afforded the free alpha-Gal trisaccharide. 相似文献
996.
N V Naryzhnaia L N Maslov Iu G Revinskaia Iu B Lishmanov 《Uspekhi fiziologicheskikh nauk》2001,32(4):73-81
The present paper has analyzed relationship between sympatico-adrenal and opioid systems in the pathogenesis of stress heart damage. Based on the our own results and other investigator data the authors make a conclusion that namely relationship between opioid and sympatico-adrenal systems both on the level of the brain and on the periphery determines a degree of the heart resistance to the injury action of severe stress. Myocardial protection by opioids at stress was found to be mediated by the peripheral mu-opioid receptors and was associated with decrease in an activity of sympatico-adrenal system and a inhibition of its effector part. On contrary central opioid system activation leads to an increase in stress heart damage via an increase in sympathetical influence on the myocardium. 相似文献
997.
The lagena (the third otolith endorgan in vertebrates) 总被引:1,自引:1,他引:0
V. I. Khorevin 《Neurophysiology》2008,40(2):142-159
In this review, the structure and functions of the lagena (the third otolith organ) in an evolutionary lineage of the vertebrates
are described and discussed. The lagenar macula appears first in the posterior part of the sacculus of elasmobranchs; in these
animals, the lagena is considered to be involved in the balance support (orientation with respect to the gravitation force).
The lagena as a separate endorgan has been described in teleost fishes; in some species, the lagena is connected with the
sacculus, while in other species the interrelations of these structures can be dissimilar. The lagena supplements the functions
of the sacculus; in fishes (animals with no special organ of hearing), it is involved in discrimination of sound oscillations,
identification of the gravitation vector, and orientation in the course of movements within the vertical plane. In amphibians,
the lagena is localized in the posterior part of the sacculus, near the auditory structures; it performs mostly vestibular
and (to a much lesser extent) auditory functions. In amniotes, the lagena was first separated from the sacculus; it is localized
in the cochlear canal, distally with respect to the hearing organ. Information on the functions of the lagena in amniotes
is rather limited and contradictory. Central projections of this organ have been examined practically only in birds. Lagenar
afferents project to the vestibular nuclei and cerebellum, while some fibers come to the auditory nuclei of the medulla. The
lagena in birds can be related to their navigation abilities (birds are supposed to be capable of orienting within the magnetic
field of the Earth due to the magnetic properties of the lagenar otoconia; this structure can also provide detection of movements
along the vertical axis. The close proximity between the otolithic and auditory endorgans in the cochlear canal of amniotes
can be indicative of the functional significance of these interrelations. This aspect, however, remains at present undiscovered.
In mammals (except Monotremata), there is no lagena as an independent endorgan.
Neirofiziologiya/Neurophysiology, Vol. 40, No. 2, pp. 160–178, March–April, 2008. 相似文献
998.
Equations for the motion of an individual dust grain in the double layer of a negatively charged cylindrical probe in a glow discharge plasma are derived and solved numerically. The distribution of the electric potential near the probe is determined, and the grain charge is calculated as a function of the distance from the probe for different probe potentials. The trajectories of grains with different initial energies are traced. An analysis of the grain trajectories shows that, at a certain distance from the probe, high-energy grains may be recharged; i.e., the grain charge may change sign. The grains are found to have no direct effect on the probe current in a dusty plasma of a glow discharge. 相似文献
999.
EEG correlates of two main effects of long-term hyperventilation (cyclic breathing similar to rebirthing), namely, psychotic manifestations and sensations in internal organs, are considered. Standard EEGs of 44 subjects were recorded and subsequently treated by multiparametric methods. It was shown that, in the case of psychotic phenomena (hallucinations, visual and auditory images, different scenes, virtual travels, out-of-body experiences, etc.), the changes in the spatial organization of bioelectric potentials as compared with the baseline have different patterns than in the case of sensations in internal organs. The changes are observed in the frontal regions of the cortex: a decrease in spatial synchronization (linear processes) during an increase in spatial disarray (nonlinear processes) of bioelectric potentials and the intensifying of high-frequency β activity. If sensations in internal organs appear, a decrease in the above parameters was observed in the right hemisphere and in posterior cortical areas. The data are discussed from the viewpoint of qualitative specificity of changes in functional states during an altered state of consciousness with manifestations of different psychovisceral phenomena. 相似文献
1000.
I. Boubriak T. Akimkina V. Polischuk A. Dmitriev S. McCready D. Grodzinsky 《Cytology and Genetics》2016,50(6):381-399
Thirty years after the Chernobyl explosion we still lack information regarding the genetic effects of radionuclide contamination on the plant population. For example, are plants adapting to the low dose of chronic ionising irradiation and showing improved resistance to radiation damage? Are they coping with changing/increased pathogenicity of fungi and viruses in the Chernobyl exclusion (ChE) zone? Are plant populations rapidly accumulating mutational load and should we expect rapid micro-evolutionary changes in plants in the Chernobyl area? This review will try to summarise the current knowledge on these aspects of plant genetics and ecology and draw conclusions on the importance of further studies in the area around Chernobyl. 相似文献