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排序方式: 共有925条查询结果,搜索用时 31 毫秒
61.
Gul M Ciragil P Bulbuloglu E Aral M Alkis S Ezberci F 《Acta microbiologica et immunologica Hungarica》2007,54(3):317-321
Comamonas testosteroni is an uncommon isolate in the clinical laboratory as a human pathogen. C. testosteroni most commonly emerges in abdominal pathologies especially in perforated appendicitis. In Turkey we report first time a case of bacteremia due to this organism, in a 22-year-old man with perforated acute appendicitis. The organism was shown to be susceptible to routine antibiotics so it was easily eliminated even after having caused a bacteremia. 相似文献
62.
Canakci S Inan K Kacagan M Belduz AO 《Journal of microbiology and biotechnology》2007,17(8):1262-1270
Some hot springs located in the west of Turkey were investigated with respect to the presence of thermophilic microorganisms. Based on phenotyping characteristics and 16S rRNA gene sequence analysis, 16 of the isolates belonged to the genus Geobacillus and grew optimally at about 60 degrees C on nutrient agar. 16S rRNA gene sequence analysis showed that these isolates resembled Geobacillus species by > or = 97%, but SDS-PAGE profiles of these 16 isolates differ from some of the other species of the genus Geobacillus. However, it is also known that analysis of 16S rRNA gene sequences may be insufficient to distinguish between some species. It is proposed that recN sequence comparisons could accurately measure genome similarities for the Geobacillus genus. Based on recN sequence analysis, isolates 11, IT3, and 12 are strains of G stearothermophilus; isolate 14.3 is a strain of G thermodenitrificans; isolates 9.1, IT4.1, and 4.5 are uncertain and it is required to make further analysis. The presence of xylanase and arabinofuranosidase activities, and their optimum temperature and pH were also investigated. These results showed that 7 of the strains have both xylanase and arabinofuranosidase activities, 4 of them has only xylanase, and the remaning 5 strains have neither of these activities. The isolates 9.1, 7.1, and 3.3 have the highest temperature optima (80 degrees C), and 7.2, 9.1, AO4, 9.2, and AO17 have the highest pH optima (pH 8) of xylanase. Isolates 7.2, AO4, AC15, and 12 have optimum arabinofuranosidase activities at 75 degrees C, and only isolate AC 15 has the lowest pH of 5.5. 相似文献
63.
64.
Gamsizkan M Demiriz M Karslioğlu Y Günhan O 《Analytical and quantitative cytology and histology / the International Academy of Cytology [and] American Society of Cytology》2007,29(3):153-158
OBJECTIVE: Early stage mycosis fungoides (MF) may be indistinguishable from some inflammatory dermatoses (IDs) histopathologically. Various morphologic features of lymphocytes in epidermis and dermis may help to differentiate early-stage MF from other IDs. STUDY DESIGN: We studied 25 cases of early-stage MF and 30 cases of various IDs with prominent exocytosis. The following nuclear variables were measured on dermal and epidermal lymphocytes in MF and IDs (control) groups: nuclear area and perimeter, area convex hull, perimeter convex hull, diameter equivalent circle, minimum feret, maximum feret and form factor. All measurements were done using routinely prepared and hematoxylin-eosin-stained slides. RESULTS: There were statistically significant differences (p < 0.01) for all of the morphometric variables between early-stage MF and IDs. CONCLUSION: Our results revealed that the nuclear contour irregularities of intraepidermal lymphocytes are higher than those of dermal lymphocytes in MF. Their nuclear geometry is also different. Comparison of the nuclear features of intraepidermal with dermal lymphocytes may provide additional support in the diagnosis of early-stage MF. 相似文献
65.
Rodrigo J Pena A Murat B Trueba M Durroux T Guillon G Rognan D 《Molecular endocrinology (Baltimore, Md.)》2007,21(2):512-523
Starting from the 2.8-A resolution x-ray structure of bovine rhodopsin, three-dimensional molecular models of the complexes between arginine vasopressin and two receptor subtypes (V1a, V1b) have been built. Amino acid sequence alignment and docking studies suggest that four key residues (1.35, 2.65, 4.61, and 5.35) fine tune the binding of vasopressin and related peptide agonists to both receptor subtypes. To validate these predictions, a series of single or double mutants were engineered at V1a and V1b receptor subtypes and tested for their binding and functional properties. Two negatively charged amino acids at positions 1.35 and 2.65 are key anchoring residues to the Arg8 residue of arginine vasopressin. Moreover, two amino acids (V(4.61) and P(5.35)) delineating a hydrophobic subsite at the human V1b receptor are responsible for the recognition of V1b selective peptide agonists. Last, one of the latter positions (5.35) is hypothesized to explain the pharmacological species differences between rat and human vasopressin receptors for a V1b peptide agonist. Altogether these refined three-dimensional models of V1a and V1b human receptors should enable the identification of further new selective V1a and V1b agonists as pharmacological but also therapeutic tools. 相似文献
66.
Our analysis highlights common statistical features of high-impact articles; we also show how information flows among various publication types. 相似文献
67.
Alexander L Chernorudskiy Alejandro Garcia Eugene V Eremin Anastasia S Shorina Ekaterina V Kondratieva Murat R Gainullin 《BMC bioinformatics》2007,8(1):126
Background
Post-translational protein modification with ubiquitin, or ubiquitylation, is one of the hottest topics in a modern biology due to a dramatic impact on diverse metabolic pathways and involvement in pathogenesis of severe human diseases. A great number of eukaryotic proteins was found to be ubiquitylated. However, data about particular ubiquitylated proteins are rather disembodied. 相似文献68.
69.
Murat Akkurt Leocir Welter Erika Maul Reinhard Töpfer Eva Zyprian 《Molecular breeding : new strategies in plant improvement》2007,19(2):103-111
Sequence-characterized amplified regions markers (SCARs) were developed from six randomly amplified polymorphic DNA (RAPD)
markers linked to the major QTL region for powdery mildew (Uncinula necator) resistance in a test population derived from the cross of grapevine cultivars “Regent” (resistant) × “Lemberger”(susceptible).
RAPD products were cloned and sequenced. Primer pairs with at least 21 nucleotides primer length were designed. All pairs
were tested in the F1 progeny of “Regent” × “Lemberger”. The SCAR primers resulted in the amplification of specific bands
of expected sizes and were tested in additional genetic resources of resistant and susceptible germplasm. All SCAR primer
pairs resulted in the amplification of specific fragments. Two of the SCAR markers named ScORA7-760 and ScORN3-R produced
amplification products predominantly in resistant individuals and were found to correlate to disease resistance. ScORA7-760,
in particular, is suitable for marker-assisted selection for powdery mildew resistance and to facilitate pyramiding powdery
mildew resistance genes from various sources. 相似文献
70.
FRIZZY PANICLE Drives Supernumerary Spikelets in Bread Wheat 总被引:1,自引:0,他引:1
Oxana Dobrovolskaya Caroline Pont Richard Sibout Petr Martinek Ekaterina Badaeva Florent Murat Audrey Chosson Nobuyoshi Watanabe Elisa Prat Nadine Gautier Véronique Gautier Charles Poncet Yuriy L. Orlov Alexander A. Krasnikov Hélène Bergès Elena Salina Lyudmila Laikova Jerome Salse 《Plant physiology》2015,167(1):189-199