Plasma Physics Reports - Results of experimental studies of toroidal Alfvén eigenmodes (TAEs) in the Globus-M spherical tokamak (R = 36 cm, a = 24 cm) are reported. The experiments were... 相似文献
To date, 35 human diseases, some of which also exhibit anticipation, have been associated with unstable repeats. Anticipation
has been reported in a number of diseases in which repeat expansion may have a role in etiology. Despite the growing importance
of unstable repeats in disease, currently no resource exists for the prioritization of repeats. Here we present Satellog,
a database that catalogs all pure 1–16 repeat unit satellite repeats in the human genome along with supplementary data. Satellog
analyzes each pure repeat in UniGene clusters for evidence of repeat polymorphism. 相似文献
Hydrogel matrices for cell cultivation have been generated by two-photon laser polymerization of unsaturated chitosan derivatives and methacrylated hyaluronic acid. The adhesive and toxic properties of the matrices have been assessed, and the matrices have been shown to have a good compatibility with primary hippocampal cell cultures. The formation of morphologically normal neural networks by cells of the nervous system cultured on the surface of hydrogel matrices has been observed. The metabolic status of dissociated hippocampal cells cultured on the matrices was similar to that of the control cultures, as shown by the results of MTT reductase activity assay. Thus, matrices based on unsaturated polysaccharide derivatives crosslinked by laser irradiation showed good compatibility with differentiated cells of the nervous system and considerable potential for use in neurotransplantation. 相似文献
Doklady Biochemistry and Biophysics - The possibility of induction of cytogenetic damage in the bone marrow, changes in the cellularity of lymphoid organs and blood composition in mice irradiated... 相似文献
Basic experimental results on cyclotron heating of the ion plasma component in the Globus-M spherical tokamak obtained by means of the ACORD-12 charge-exchange ion analyzer are presented. A procedure for determining the maximum energy of fast ions confined in the plasma is described. The procedure was applied to estimate the limiting energy of hydrogen minority ions accelerated during ion cyclotron heating in the Globus-M tokamak. The experimental evaluation of the maximum hydrogen ion energy is confirmed by simulations of ion orbits. Recommendations for optimizing experiments on ion cyclotron heating in the Globus-M tokamak are formulated. 相似文献
We present a biological data warehouse called Atlas that locally stores and integrates biological sequences, molecular interactions,
homology information, functional annotations of genes, and biological ontologies. The goal of the system is to provide data,
as well as a software infrastructure for bioinformatics research and development. 相似文献
X-ray study of chicken cytosolic aspartate aminotransferase revealed conformational changes in the protein of two kinds: (1) a shift of the small domain adjacent to substrate-binding area due to interaction of the protein with two carboxyl groups of substrate and (2) a change in inclination of the coenzyme plane due to replacement of C = N bond of the coenzyme with Lys-258 by C = N bond with a substrate. An asymmetry in subunit behaviour is observed in both cases: the domain is shifted in one subunit and the coenzyme is rotated in other. Substrate-binding properties of each subunit are strictly dependent on the protein conformation in substrate-binding area. 相似文献
A series of three star-shaped compounds containing both donor (carbazole) and acceptor (2,4,6-triphenyl-1,3,5-triazine) moieties linked through various linking bridges was studied theoretically at the linear response TD-DFT level of theory to describe their absorption and fluorescence spectra. The concept of a localized charge-transfer excited state has been applied successfully to explain the observed strong solvatochromic effect in the emission spectra of the studied molecules, which can be utilized for the fabrication of color tunable solution-processable OLEDs. The concept is in particularly applicable to donor–acceptor species with a C3 symmetry point group where the static dipole moment changes dramatically upon electronic excitation. An important peculiarity of the studied molecules is that they are characterized by non-zero values of the HOMO and LUMO orbitals in the same common part of molecular space that provides a large electric dipole transition moment for both light absorption and emission.
