全文获取类型
收费全文 | 108506篇 |
免费 | 9502篇 |
国内免费 | 46篇 |
专业分类
118054篇 |
出版年
2023年 | 365篇 |
2022年 | 760篇 |
2021年 | 1711篇 |
2020年 | 1007篇 |
2019年 | 1262篇 |
2018年 | 1829篇 |
2017年 | 1647篇 |
2016年 | 2599篇 |
2015年 | 4099篇 |
2014年 | 4677篇 |
2013年 | 5659篇 |
2012年 | 7967篇 |
2011年 | 8069篇 |
2010年 | 5047篇 |
2009年 | 4368篇 |
2008年 | 6732篇 |
2007年 | 6702篇 |
2006年 | 6467篇 |
2005年 | 6155篇 |
2004年 | 5966篇 |
2003年 | 5666篇 |
2002年 | 5392篇 |
2001年 | 1756篇 |
2000年 | 1690篇 |
1999年 | 1506篇 |
1998年 | 1475篇 |
1997年 | 1004篇 |
1996年 | 973篇 |
1995年 | 842篇 |
1994年 | 802篇 |
1993年 | 849篇 |
1992年 | 789篇 |
1991年 | 763篇 |
1990年 | 697篇 |
1989年 | 582篇 |
1988年 | 640篇 |
1987年 | 548篇 |
1986年 | 494篇 |
1985年 | 619篇 |
1984年 | 724篇 |
1983年 | 573篇 |
1982年 | 696篇 |
1981年 | 672篇 |
1980年 | 544篇 |
1979年 | 482篇 |
1978年 | 450篇 |
1977年 | 415篇 |
1976年 | 371篇 |
1975年 | 329篇 |
1974年 | 356篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
41.
Ralf Heinrich Peter Bräunig Ismeni Walter Henning Schneider Edward A. Kravitz 《Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology》2000,186(7-8):617-629
In the American lobster (Homarus americanus) the biogenic amines serotonin and octopamine appear to play important and opposite roles in the regulation of aggressive behavior, in the establishment and/or maintenance of dominant and subordinate behavioral states and in the modulation of the associated postural stances and escape responses. The octopamine-containing neurosecretory neurons in the thoracic regions of the lobster ventral nerve cord fall into two morphological subgroups, the root octopamine cells, a classical neurohemal group with release regions along second thoracic roots, and the claw octopamine cells, a group that selectively innervates the claws. Cells of both subgroups have additional sets of endings within neuropil regions of ganglia of the ventral nerve cord. Octopamine neurosecretory neurons generally are silent, but when spontaneously active or when activated, they show large overshooting action potentials with prominent after-hyperpolarizations. Autoinhibition after high-frequency firing, which is also seen in other crustacean neurosecretory cells, is readily apparent in these cells. The cells show no spontaneous synaptic activity, but appear to be excited by a unitary source. Stimulation of lateral or medial giant axons, which excite serotonergic cells yielded no response in octopaminergic neurosecretory cells and no evidence for direct interactions between pairs of octopamine neurons, or between the octopaminergic and the serotonergic sets of neurosecretory neurons was found. 相似文献
42.
43.
Expanded thermal niche for a diving vertebrate: A leatherback turtle diving into near-freezing water
Michael C. James Graeme C. Hays 《Journal of experimental marine biology and ecology》2006,335(2):221-226
The global distribution of extant reptiles is more limited than that of mammals or birds, with low reptilian species diversity at high latitudes. Central to this limited geographical distribution is the ectothermic nature of reptiles, which means that they generally become torpid at cold temperatures. However, here we report the first detailed telemetry from a leatherback turtle (Dermochelys coriacea) diving in cold water at high latitude. An individual equipped with a satellite tag that relayed temperature-depth profiles dived continuously for many weeks into sub-surface waters as cold as 0.4 °C. Global warming will likely increase the foraging range of leatherback turtles further into temperate and boreal waters. 相似文献
44.
45.
Bennett Michael D.; Johnston Spencer; Hodnett George L.; Price H. James 《Annals of botany》2000,85(3):351-357
In 1965 Van't Hof estimated the nuclear DNA amount of an unidentifiedAllium cepa L. cultivar as 2C = 33.55 pg (Experimental CellResearch39: 858). This value has been adopted by commonusage as the main calibration standard for angiosperm DNA C-valueestimations. However, different cultivars have been used whileassuming species DNA C-value constancy. Surprisingly this assumptionhas never been tested. A. cepa is an outbreeder with telomericheterochromatic segments, so intraspecific variation in C-value,possibly correlated with environmental factors as seen in Zeamays L., might be expected. We used laser flow cytometry tocompare nuclear DNA amounts in roots of six A. cepa cultivarsused as calibration standards or from different environments.Tissues from one cultivar, or similar volumes of tissue fromtwo cultivars, were run and the variance between nuclei in 2Cpeaks compared. Only one shoulderless 2C peak was seen for allpairs of co-chopped cultivars. Thus, no large differences inC-value between cultivars from different environments were found.Moreover, comparing cultivars run singly or as pairs showedno evidence for increased variation in 2C peaks in the latter,and hence of critical differences in DNA amounts between AilsaCraig and another cultivar. Such variation was insufficientto make their use as alternative calibration standards, or thepractice of imputing Van't Hof's original C-value estimate tothem, unacceptable for most practical purposes. Given the mechanismsknown which can generate genome size variation, the degree ofconstancy in DNA C-value found seems remarkable. Copyright 2000Annals of Botany Company Allium cepa, onion cultivars, calibration standards, DNA C-value constancy, flow cytometry 相似文献
46.
New class I and II HLA alleles strongly associated with opposite patterns of progression to AIDS. 总被引:10,自引:0,他引:10
H Hendel S Caillat-Zucman H Lebuanec M Carrington S O'Brien J M Andrieu F Sch?chter D Zagury J Rappaport C Winkler G W Nelson J F Zagury 《Journal of immunology (Baltimore, Md. : 1950)》1999,162(11):6942-6946
The genetics of resistance to infection by HIV-1 cohort consists of 200 slow and 75 rapid progressors to AIDS corresponding to the extremes of HIV disease outcome of 20,000 Caucasians of European descent. A comprehensive analysis of HLA class I and class II genes in this highly informative cohort has identified HLA alleles associated with fast or slow progression, including several not described previously. A quantitative analysis shows an overall HLA influence independent of and equal in magnitude (for the protective effect) to the effect of the CCR5-Delta32 mutation. Among HLA class I genes, A29 (p = 0.001) and B22 (p < 0.0001) are significantly associated with rapid progression, whereas B14 (p = 0.001) and C8 (p = 0.004) are significantly associated with nonprogression. The class I alleles B27, B57, C14 (protective), and C16, as well as B35 (susceptible), are also influential, but their effects are less robust. Influence of class II alleles was only observed for DR11. These results confirm the influence of the immune system on disease progression and may have implications on peptide-based vaccine development. 相似文献
47.
Michael W. Shiflett Kristy L. Gould Tom V. Smulders Timothy J. DeVoogd 《Developmental neurobiology》2002,51(3):215-222
The hippocampal formation (HF) of food‐storing birds is larger than non‐storing species, and the size of the HF in food‐storing Black‐Capped Chickadees (Poecile atricapillus) varies seasonally. We examined whether the volume of the septum, a medial forebrain structure that shares reciprocal connections with the HF, demonstrates the same species and seasonal variation as has been shown in the HF. We compared septum volume in three parid species; non‐storing Blue Tits (Parus caeruleus) and Great Tits (Parus major), and food‐storing Black‐Capped Chickadees. We found the relative septum volume to be larger in chickadees than in the non‐storing species. We also compared septum and nucleus of the diagonal band (NDB) volume of Black‐Capped Chickadees at different times of the year. We found that the relative septum volume varies seasonally in food‐storing birds. The volume of the NDB does not vary seasonally. Due to the observed species and seasonal variation, the septum, like the hippocampal formation of food‐storing birds, may be specialized for some aspects of food‐storing and spatial memory. © 2002 Wiley Periodicals, Inc. J Neurobiol 51: 215–222, 2002 相似文献
48.
Risk assessment is part of the risk analysis process as it is used in veterinary medicine to estimate risks related to international trade and food safety. Data from monitoring and surveillance systems (MO&SS) are used throughout the risk assessment process for hazard identification, release assessment, exposure assessment and consequence assessment. As the quality of risk assessments depends to a large extent on the availability and quality of input data, there is a close relationship between MO&SS and risk assessment. In order to improve the quality of risk assessments, MO&SS should be designed according to minimum quality standards. Second, recent scientific developments on state-of-the-art design and analysis of surveys need to be translated into field applications and legislation. Finally, knowledge about the risk assessment process among MO&SS planners and managers should be promoted in order to assure high-quality data. 相似文献
49.
50.