全文获取类型
收费全文 | 126篇 |
免费 | 9篇 |
国内免费 | 1篇 |
专业分类
136篇 |
出版年
2023年 | 2篇 |
2022年 | 4篇 |
2021年 | 1篇 |
2020年 | 4篇 |
2019年 | 2篇 |
2018年 | 9篇 |
2017年 | 3篇 |
2016年 | 5篇 |
2015年 | 6篇 |
2014年 | 6篇 |
2013年 | 6篇 |
2012年 | 8篇 |
2011年 | 10篇 |
2010年 | 3篇 |
2009年 | 7篇 |
2008年 | 4篇 |
2007年 | 8篇 |
2006年 | 6篇 |
2005年 | 6篇 |
2004年 | 1篇 |
2003年 | 6篇 |
2002年 | 3篇 |
2001年 | 4篇 |
2000年 | 2篇 |
1999年 | 1篇 |
1998年 | 2篇 |
1997年 | 4篇 |
1994年 | 1篇 |
1989年 | 1篇 |
1983年 | 1篇 |
1982年 | 3篇 |
1978年 | 1篇 |
1977年 | 1篇 |
1976年 | 1篇 |
1973年 | 1篇 |
1971年 | 1篇 |
1969年 | 1篇 |
1968年 | 1篇 |
排序方式: 共有136条查询结果,搜索用时 0 毫秒
11.
Victor Melnikov Falk Pollehne Natalia Minkina Lidia Melnik 《Journal of fish biology》2021,99(4):1393-1402
Understanding what environmental drivers influence marine predator–prey relationships can be key to managing and protecting ecosystems, especially in the face of future climate change risks. This is especially important in environments such as the Black Sea, where strong biogeochemical gradients can drive marine habitat partitioning and ecological interactions. We used underwater video recordings in the north-eastern Black Sea in November 2013 to observe the distribution and behaviour of the Black Sea sprat (Sprattus sprattus phalericus, Risso 1827) and its zooplankton prey. Video recordings have shown that the Black Sea sprat S. sprattus phalericus tolerates severely hypoxic waters near the redoxcline. The school was distributed in the 33–96 m layer [oxygen concentration (O2) 277–84 μmol L−1]. Some individuals were observed to leave the school and descended 20 m deeper for foraging on copepods in the 119–123 m layer (O2 12–10 μmol L−1). Zooplankton appeared concentrated on the upper boundary of the suboxic zone (O2 < 10 μmol L−1). No zooplankton were observed below O2 6–7 μmol L−1 (128 m). Understanding the ability of this species to tolerate low oxygen waters is crucial to predicting future responses to natural and anthropogenic changes in hypoxia. 相似文献
12.
S. R. Badu R. Melnik M. Paliy S. Prabhakar A. Sebetci B. A. Shapiro 《European biophysics journal : EBJ》2014,43(10-11):555-564
In this study, we construct novel RNA nanoclusters, RNA nanotubes made of several nanorings up to the size of 20 nm, utilizing the molecular dynamics simulation, and study their structural properties [i.e., the root mean square deviation, the radius of gyration and the radial distribution function (RDF)] in physiological solutions that can be used for drug delivery into the human body. The patterns of energy and temperature variations of the systems are also discussed. Furthermore, we study the concentration of ions around the tube as a function of time at a particular temperature. We have found that when the temperature increases, the number of ions increases within a certain distance of the tube. We report that the number of ions within this distance around the tubes decreases in quenched runs. This indicates that some ions evaporate with decrease in temperature, as has been observed in the case of the nanoring. RDF plots also demonstrate a similar trend with temperature, as was found in the case of RNA nanorings. 相似文献
13.
A. D. Melnik N. N. Bakharev V. K. Gusev P. R. Goncharov G. S. Kurskiev V. B. Minaev Yu. V. Petrov N. V. Sakharov A. Yu. Telnova S. Yu. Tolstyakov F. V. Chernyshev P. B. Shchegolev 《Plasma Physics Reports》2017,43(8):805-817
Specific features of the energy distributions of fast ions during neutral beam injection at the Globus-М tokamak are considered. Different loss mechanisms that can lead to the formation of a specific shape of the energy spectrum of superthermal ions are analyzed. The effect of sawtooth oscillations on the loss of fast ions is discussed. 相似文献
14.
Melnik BS Molochkov NV Prokhorov DA Uversky VN Kutyshenko VP 《Biochimica et biophysica acta》2011,1814(12):1930-1939
The peculiarities of thermal denaturation and interaction with water of the cycle-3 mutant of green fluorescent protein (GFP) were analyzed by NMR techniques and compared with those of bovine carbonic anhydrase II (BCA-II). Irreversible thermal denaturation was accompanied by massive GFP aggregation with no detectable accumulation of soluble denatured protein. Analysis of the spin diffusion data suggested that the internal part of the GFP β-can is involved in intensive interactions with water molecules. As a result, at high temperatures, the GFP structure does not unfold but rather breaks, consequently leading to enhanced protein aggregation. This is very different from typical BCA-II behavior. 相似文献
15.
16.
17.
In human serum, polymorphism of apoA-II predominantly in HDL3 could be demonstrated. HDL3-apoA-II was composed of four isoproteins, each with a molecular weight of 8600 (reduced form) and identical immunological properties. The isoproteins are designated apoA-II-1 (pI 5.16), apoA-II-2 (pI 4.89) corresponding to the already known apoA-II monomer band, apoA-II-3 (pI 4.58), and apoA-II-4 (pI 4.31). The amino acid compositions of the A-II isoproteins were virtually identical with the published data for apoA-II. Treatment with acid phosphatase, alkaline phosphatase, or neuraminidase before electrophoresis did not alter the apoA-II pattern. The apoA-II isoprotein pattern was studied in ten male and ten female normolipidemic volunteers, in two patients with Tangier disease, and in three patients with abetalipoproteinemia. The isoelectric focusing patterns of apoA-II appeared virtually identical in all subjects. However, in Tangier disease, due to the low apo-A-II concentration, only apoA-II-1 and apoA-II-2 were detectable, and in abetalipoproteinemia a different relative distribution pattern of the individual isoforms was found as compared to normal HDL3. Our studies indicate that apoA-II, similar to apoA-I, exists in several isoforms. The relationship of these isoforms to each other is at present unclear. They may originate from relatively basic isoproteins that are modified in charge by post-translational processes such as proteolytic cleavage, sequential deamidation, or other mechanisms. 相似文献
18.
O. N. Leonov M. L. Tsyrenina E. I. Melnik V. M. Devichenskii L. Yu. Kryukova E. A. Vorontsov S. L. Kuznetsov L. N. Kryukov 《Russian Journal of Bioorganic Chemistry》2000,26(5):334-336
A series of uracil and theophylline derivatives was synthesized. 4-Amino-1,3-dimethyl-5-non-anoylaminouracil displayed the
most pronounced effect of thein vitro stimulation of the 2-deoxyglucose transport into hepatic rat cells.
Deceased. 相似文献
19.
The influence of nerve growth factor on the activities of adenylate cyclase and high-affinity GTPase in pheochromocytoma PC12 cell 总被引:1,自引:0,他引:1
The influence of nerve growth factor (NGF) on the activities of adenylate cyclase and high-affinity GTPase in pheochromocytoma PC12 cells was studied. Incubation of cells with nerve growth factor led to a rapid activation of adenylate cyclase accompanied by an inhibition of high-affinity GTPase. By the 10th min of incubation the activity of adenylate cyclase had been reduced 2-fold when compared to the control. The activity of GTPase, however, increased. No significant changes in the cAMP level were detected. The data obtained indicate that NGF interaction with PC12 cells induces changes in the adenylate cyclase system and this process involves G-proteins that regulate the adenylate cyclase activity. 相似文献
20.
Courtney D. Fitzhugh Matthew M. Hsieh Darlene Allen Wynona A. Coles Cassie Seamon Michael Ring Xiongce Zhao Caterina P. Minniti Griffin P. Rodgers Alan N. Schechter John F. Tisdale James G. Taylor VI 《PloS one》2015,10(11)