全文获取类型
收费全文 | 2503篇 |
免费 | 280篇 |
国内免费 | 3篇 |
出版年
2022年 | 12篇 |
2021年 | 41篇 |
2020年 | 18篇 |
2019年 | 21篇 |
2018年 | 45篇 |
2017年 | 30篇 |
2016年 | 55篇 |
2015年 | 92篇 |
2014年 | 105篇 |
2013年 | 158篇 |
2012年 | 161篇 |
2011年 | 138篇 |
2010年 | 96篇 |
2009年 | 106篇 |
2008年 | 144篇 |
2007年 | 149篇 |
2006年 | 131篇 |
2005年 | 132篇 |
2004年 | 122篇 |
2003年 | 114篇 |
2002年 | 113篇 |
2001年 | 44篇 |
2000年 | 41篇 |
1999年 | 44篇 |
1998年 | 24篇 |
1997年 | 32篇 |
1996年 | 16篇 |
1995年 | 24篇 |
1994年 | 27篇 |
1993年 | 20篇 |
1992年 | 34篇 |
1991年 | 24篇 |
1990年 | 39篇 |
1989年 | 47篇 |
1988年 | 24篇 |
1987年 | 26篇 |
1986年 | 17篇 |
1985年 | 17篇 |
1984年 | 23篇 |
1983年 | 21篇 |
1982年 | 11篇 |
1981年 | 15篇 |
1980年 | 12篇 |
1979年 | 16篇 |
1978年 | 16篇 |
1977年 | 15篇 |
1975年 | 17篇 |
1972年 | 14篇 |
1971年 | 19篇 |
1968年 | 13篇 |
排序方式: 共有2786条查询结果,搜索用时 15 毫秒
71.
72.
73.
74.
75.
Kaitlyn M. Price Karen G. Wigg Yu Feng Kirsten Blokland Margaret Wilkinson Gengming He Elizabeth N. Kerr Tasha‐Cate Carter Sharon L. Guger Maureen W. Lovett Lisa J. Strug Cathy L. Barr 《Genes, Brain & Behavior》2020,19(6)
Reading disabilities (RD) are the most common neurocognitive disorder, affecting 5% to 17% of children in North America. These children often have comorbid neurodevelopmental/psychiatric disorders, such as attention deficit/hyperactivity disorder (ADHD). The genetics of RD and their overlap with other disorders is incompletely understood. To contribute to this, we performed a genome‐wide association study (GWAS) for word reading. Then, using summary statistics from neurodevelopmental/psychiatric disorders, we computed polygenic risk scores (PRS) and used them to predict reading ability in our samples. This enabled us to test the shared aetiology between RD and other disorders. The GWAS consisted of 5.3 million single nucleotide polymorphisms (SNPs) and two samples; a family‐based sample recruited for reading difficulties in Toronto (n = 624) and a population‐based sample recruited in Philadelphia [Philadelphia Neurodevelopmental Cohort (PNC)] (n = 4430). The Toronto sample SNP‐based analysis identified suggestive SNPs (P ~ 5 × 10?7) in the ARHGAP23 gene, which is implicated in neuronal migration/axon pathfinding. The PNC gene‐based analysis identified significant associations (P < 2.72 × 10?6) for LINC00935 and CCNT1, located in the region of the KANSL2/CCNT1/LINC00935/SNORA2B/SNORA34/MIR4701/ADCY6 genes on chromosome 12q, with near significant SNP‐based analysis. PRS identified significant overlap between word reading and intelligence (R2 = 0.18, P = 7.25 × 10?181), word reading and educational attainment (R2 = 0.07, P = 4.91 × 10?48) and word reading and ADHD (R2 = 0.02, P = 8.70 × 10?6; threshold for significance = 7.14 × 10?3). Overlap was also found between RD and autism spectrum disorder (ASD) as top‐ranked genes were previously implicated in autism by rare and copy number variant analyses. These findings support shared risk between word reading, cognitive measures, educational outcomes and neurodevelopmental disorders, including ASD. 相似文献
76.
Pedro Len‐Lobos Marcela A. Bustamante‐Snchez Cara R. Nelson Diego Alarcn Rodrigo Hasbún Michael Way Hugh W. Pritchard Juan J. Armesto 《Restoration Ecology》2020,28(2):277-281
We argue that the need for a quality seed supply chain is a major bottleneck for the restoration of Chile's native ecosystems, thus supplementing the list of bottlenecks proposed by Bannister et al. in 2018. Specifically, there is a need for defining seed transfer zones, developing standards and capacities for properly collecting and storing seeds, reducing information gaps on seed physiology and longevity, and implementing an efficient seed supply chain with certification of seed origin and quality. Without such capacities, countries are unlikely to meet their restoration commitments. Although we focus on bottlenecks in Chile, the issues we raise are relevant to other countries and thus the global agenda for ecological restoration. 相似文献
77.
Caroline R. Cummings Sonia M. Hernandez Maureen Murray Taylor Ellison Henry C. Adams Robert E. Cooper Shannon Curry Kristen J. Navara 《Ecology and evolution》2020,10(15):8416-8428
When wildlife forage and/or live in urban habitats, they often experience a shift in resource availability and dietary quality. Some species even use human handouts, such as bread, as well as human refuse, as a large part of their new diets; yet the influences of this nutritional shift on health and survival remain unclear. American white ibises are increasingly being seen in urban areas in Florida; they collect handouts, such as bread and other food items, from humans in parks, and are also found foraging on anthropogenic sources in trash heaps. We hypothesized that the consumption of these new anthropogenic food sources may trigger increases in indicators of physiological challenge and dampen immune responses. We tested this experimentally by raising 20 white ibis nestlings in captivity, and exposing 10 to a simulated anthropogenic diet (including the addition of white bread and a reduction in seafood content) while maintaining 10 on a diet similar to what ibises consume in more natural environments. We then tested two indicators of physiological challenge (corticosterone and heat shock protein 70), assessed innate immunity in these birds via bactericidal assays and an in vitro carbon clearance assay, and adaptive immunity using a phytohemagglutinin skin test. The anthropogenic diet depressed the development of the ability to kill Salmonella paratyphi in culture. Our results suggest that consuming an anthropogenic diet may be detrimental in terms of the ability to battle a pathogenic bacterial species, but there was little effect on indicators of physiological challenge and other immunological measures. 相似文献
78.
79.
Sahoo Kamalakanta Upadhyay Amit Runge Troy Bergman Richard Puettmann Maureen Bilek Edward 《The International Journal of Life Cycle Assessment》2021,26(1):189-213
The International Journal of Life Cycle Assessment - Producing biochar from forest residues can help resolve environmental issues by reducing forest fires and mitigating climate change. However,... 相似文献
80.
Temperature plays a key role in the biology of ectotherms, including anurans, which are found at higher elevations in the tropics than anywhere in the temperate zone. High elevation tropical environments are characterized by extreme daily thermal fluctuation including high daily maxima and nightly freezing. Our study investigated the contrasting operative temperatures of the anurans Telmatobius marmoratus and Pleurodema marmoratum in different environmental contexts at the same elevation and biome above 5,200 m. Telmatobius marmoratus avoids extremes of daily temperature fluctuation by utilizing thermally buffered aquatic habitat at all life stages, with minimal operative temperature variation (range: 4.6–8.0°C). Pleurodema marmoratum, in contrast, experienced operative temperatures from ?3.5 to 44°C and has one of the widest thermal breadths reported for any tropical frog, from >32°C (critical thermal maximum) to surviving freezing periods of 1 and 6 hr down to ?3.0°C. Our findings expand experimental evidence of frost tolerance in amphibians to the widespread Neotropical family Leptodactylidae, the first such evidence of frost tolerance in a tropical amphibian. Our study identifies three strategies (wide thermal tolerance breadth, use of buffered microhabitats, and behavioral thermoregulation), which allow these tropical frogs to withstand the current wide daily thermal fluctuation above 5,000 m.a.s.l. and which may help them adapt to future climatic changes. Abstract in Spanish is available with online material 相似文献