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211.
Distribution of chymase-containing mast cells in human bronchi. 总被引:5,自引:0,他引:5
R Matin E K Tam J A Nadel G H Caughey 《The journal of histochemistry and cytochemistry》1992,40(6):781-786
Mast cell chymase stimulates secretion from cultured airway gland serous cells and hydrolyzes bronchoactive peptides in vitro. To explore the likelihood of these interactions occurring in situ, we examined the distribution and concentration of chymase-containing mast cells near glands and smooth muscle of major human bronchi from eight individuals without known airway disease. Total airway mast cells and the subset of mast cells containing chymase were detected by staining for methylene blue metachromasia and chloroacetate esterase activity, respectively. The percentage of chymase-containing mast cells was found to differ strikingly among bronchial tissue compartments. Near glands, for example, the concentration of chymase-positive mast cells (640 +/- 120 cells/mm3) was 73 +/- 9% that of total mast cells (910 +/- 130 cells/mm3), whereas in smooth muscle the concentration of chymase-positive mast cells (450 +/- 200 cells/mm3) was only 14 +/- 4% that of total mast cells (2920 +/- 620 cells/mm3). Of all chymase-containing mast cells in the airway subepithelium, 30 +/- 4% were located within 20 microns of submucosal glands. Although the percentage of chymase-containing cells varied, the absolute concentration of chymase-containing mast cells was similar in all compartments. These results reveal a differential distribution of mast cell subpopulations in human airway and suggest that mast cells containing chymase are near gland and smooth muscle targets. 相似文献
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213.
214.
A. Matin 《FEMS microbiology letters》1990,75(2-3):307-318
215.
A. S. M. Abdul Matin 《Entomologia Experimentalis et Applicata》1976,20(1):99-103
In an attempt to delay hatching without affecting their viability, the eggs ofLatheticus oryzae W. were subjected to cold treatment at 5° for varying periods and at different stages of their development. A small dose
of 0.5 krad of gamma radiation was also given at each of those temperature treatments. Most of the eggs hatched at 30° following
low-temperature exposures of 1 and 2 days. There was a significant decrease in hatch as the exposure period increased further
(P<0.05). An egg exposure to 5° also led to an increase in egg period and the increase was nearly equal to the period of cold
exposure. Radiation did not alter the situation. 相似文献
216.