全文获取类型
收费全文 | 2666篇 |
免费 | 245篇 |
国内免费 | 1篇 |
出版年
2023年 | 13篇 |
2022年 | 28篇 |
2021年 | 101篇 |
2020年 | 46篇 |
2019年 | 66篇 |
2018年 | 66篇 |
2017年 | 55篇 |
2016年 | 91篇 |
2015年 | 143篇 |
2014年 | 177篇 |
2013年 | 214篇 |
2012年 | 243篇 |
2011年 | 226篇 |
2010年 | 127篇 |
2009年 | 136篇 |
2008年 | 173篇 |
2007年 | 156篇 |
2006年 | 126篇 |
2005年 | 115篇 |
2004年 | 63篇 |
2003年 | 82篇 |
2002年 | 73篇 |
2001年 | 43篇 |
2000年 | 36篇 |
1999年 | 30篇 |
1998年 | 18篇 |
1997年 | 17篇 |
1996年 | 9篇 |
1995年 | 16篇 |
1994年 | 12篇 |
1993年 | 13篇 |
1992年 | 13篇 |
1991年 | 16篇 |
1990年 | 21篇 |
1989年 | 12篇 |
1988年 | 14篇 |
1987年 | 8篇 |
1986年 | 14篇 |
1985年 | 8篇 |
1983年 | 8篇 |
1982年 | 5篇 |
1978年 | 6篇 |
1977年 | 6篇 |
1976年 | 5篇 |
1974年 | 6篇 |
1973年 | 11篇 |
1972年 | 4篇 |
1970年 | 5篇 |
1969年 | 7篇 |
1968年 | 4篇 |
排序方式: 共有2912条查询结果,搜索用时 953 毫秒
41.
Nicolas Tromas Zofia E. Taranu Mathieu Castelli Juliana S. M. Pimentel Daniel A. Pereira Romane Marcoz B. Jesse Shapiro Alessandra Giani 《Environmental microbiology》2020,22(4):1238-1250
Understanding how ecological traits have changed over evolutionary time is a fundamental question in biology. Specifically, the extent to which more closely related organisms share similar ecological preferences due to phylogenetic conservation – or if they are forced apart by competition – is still debated. Here, we explored the co-occurrence patterns of freshwater cyanobacteria at the sub-genus level to investigate whether more closely related taxa share more similar niches and to what extent these niches were defined by abiotic or biotic variables. We used deep 16S rRNA gene amplicon sequencing and measured several abiotic environmental parameters (nutrients, temperature, etc.) in water samples collected over time and space in Furnas Reservoir, Brazil. We found that relatively more closely related Synechococcus (in the continuous range of 93%–100% nucleotide identity in 16S) had an increased tendency to co-occur with one another (i.e. had similar realized niches). This tendency could not be easily explained by shared preferences for measured abiotic niche dimensions. Thus, commonly measured abiotic parameters might not be sufficient to characterize, nor to predict community assembly or dynamics. Rather, co-occurrence between Synechococcus and the surrounding community (whether or not they represent true biological interactions) may be a more sensitive measure of realized niches. Overall, our results suggest that realized niches are phylogenetically conserved, at least at the sub-genus level and at the resolution of the 16S marker. Determining how these results generalize to other genera and at finer genetic resolution merits further investigation. 相似文献
42.
Isabel dos Santos Souza Nawal Maïssa Jason Ziveri Philippe C. Morand Mathieu Coureuil Xavier Nassif Sandrine Bourdoulous 《Cellular microbiology》2020,22(4)
Neisseria meningitidis (meningococcus) is a Gram‐negative bacterium responsible for two devastating forms of invasive diseases: purpura fulminans and meningitis. Interaction with both peripheral and cerebral microvascular endothelial cells is at the heart of meningococcal pathogenesis. During the last two decades, an essential role for meningococcal type IV pili in vascular colonisation and disease progression has been unravelled. This review summarises 20 years of research on meningococcal type IV pilus‐dependent virulence mechanisms, up to the identification of promising anti‐virulence compounds that target type IV pili. 相似文献
43.
44.
Fabrizio Gianni Vesna Ma
i Fabrizio Bartolini Alexis Pey Mathieu Laurent Luisa Mangialajo 《Restoration Ecology》2020,28(4):750-756
The role of herbivorous fish in threatening marine forests of temperate seas has been generally overlooked. Only recently, the scientific community has highlighted that high fish herbivory can lead to regime shifts from canopy‐forming algae to less complex turf communities. Here, we present an innovative herbivorous fish deterrent device (DeFish), which can be used for conservation and restoration of marine forests. Compared to most traditional fish exclusion systems, such as cages, the DeFish system does not need regular cleaning and maintenance, making it more cost‐efficient. Resistance of DeFish was tested by installing prototypes at different depths in the French Riviera and in Montenegro: more than 60% of the devices endured several years without maintenance, even if most of them were slightly damaged in the exposed site in Montenegro. The efficacy of DeFish in limiting fish herbivory was tested by an exclusion experiment on Cystoseira amentacea in the French Riviera. In a few months, the number of fish bite marks on the seaweed was decreased, causing a consequent increase in algal length. The device here presented has been conceived for Mediterranean canopy‐forming algae, but the same concept can be applied to other species vulnerable to fish herbivory, such as kelps or seagrasses. In particular, the DeFish design could be improved using more robust and biodegradable materials. Innovative engineering systems, such as DeFish, are expected to become useful tools in the conservation and restoration of marine forests, to complement other practices including active reforestation, herbivore regulation, and regular monitoring of their status. 相似文献
45.
Ping Ren Valrie Nron Sergio Rossi Eryuan Liang Mathieu Bouchard Annie Deslauriers 《Global Change Biology》2020,26(4):2072-2080
Climate change is altering phenology; however, the magnitude of this change varies among taxa. Compared with phenological mismatch between plants and herbivores, synchronization due to climate has been less explored, despite its potential implications for trophic interactions. The earlier budburst induced by defoliation is a phenological strategy for plants against herbivores. Here, we tested whether warming can counteract defoliation‐induced mismatch by increasing herbivore‐plant phenological synchrony. We compared the larval phenology of spruce budworm and budburst in balsam fir, black spruce, and white spruce saplings subjected to defoliation in a controlled environment at temperatures of 12, 17, and 22°C. Budburst in defoliated saplings occurred 6–24 days earlier than in the controls, thus mismatching needle development from larval feeding. This mismatch decreased to only 3–7 days, however, when temperatures warmed by 5 and 10°C, leading to a resynchronization of the host with spruce budworm larvae. The increasing synchrony under warming counteracts the defoliation‐induced mismatch, disrupting trophic interactions and energy flow between forest ecosystem and insect populations. Our results suggest that the predicted warming may improve food quality and provide better growth conditions for larval development, thus promoting longer or more intense insect outbreaks in the future. 相似文献
46.
47.
Prasanna Maruthi Podsiadla-Bialoskorska Malgorzata Mielecki Damian Ruffier Nicolas Fateh Amina Lambert Annie Fanuel Mathieu Camberlein Emilie Szolajska Ewa Grandjean Cyrille 《Glycoconjugate journal》2021,38(4):437-446
Glycoconjugate Journal - Virus-Like Particles (VLPs) have been used as immunogenic molecules in numerous recombinant vaccines. VLPs can also serve as vaccine platform to exogenous antigens, usually... 相似文献
48.
Khaoula Rochdi Cerino Mathieu Da Silva Nathalie Delague Valerie Nahili Halima Kriouile Yamna Gorokhova Svetlana Bartoli Marc Saïle Rachid Barakat Abdelhamid Krahn Martin 《Molecular biology reports》2021,48(10):6999-7006
Molecular Biology Reports - Congenital myasthenic syndromes (CMS) are associated with defects in the structure and the function of neuromuscular junctions. These rare disorders can result from... 相似文献
49.
Bobby G. Ng Paulina Sosicka François Fenaille Annie Harroche Sandrine Vuillaumier-Barrot Mindy Porterfield Zhi-Jie Xia Shannon Wagner Michael J. Bamshad Marie-Christine Vergnes-Boiteux Sophie Cholet Stephen Dalton Anne Dell Thierry Dupré Mathieu Fiore Stuart M. Haslam Yohann Huguenin Tadahiro Kumagai Hudson H. Freeze 《American journal of human genetics》2021,108(6):1040-1052
50.
Marius Dhamelincourt Mathieu Buoro Jacques Rives Stellia Sebihi Cédric Tentelier 《Journal of fish biology》2021,98(2):557-565
Nest building relates to reproductive effort, sexual selection, intersexual conflict and cooperation and may be linked to individual phenotype and interindividual interactions. In particular, larger individuals having more energy reserves are expected to build more, larger nests, without having to trade intrasexual competition for cooperative nest building. Capture–mark–recapture and nest survey of sea lamprey (Petromyzon marinus L. 1758) were combined to assess the relationship between individuals and nesting activity on a spawning ground, throughout a breeding season, during which 202 nests were observed and 114 individuals were captured. On average, males and females stayed 8.33 ± 1.02 and 3.57 ± 1.04 days on the spawning ground, visited 2.26 ± 1.72 and 1.67 ± 1.17 nests and encountered 2.33 ± 2.13 mates for males and 2.29 ± 1.32 mates for females, respectively, and the number of mates encountered increased with the number of nests visited. Body size had no effect on the duration of presence on spawning ground, number of nests visited, number of individuals per nest and sex ratio on nest or nest volume. Bigger nests were found at the end of the season and were not necessarily built by more individuals. This work brings insights on the mating system and cooperative nest building in sea lamprey and may inform managers who want to estimate sea lamprey populations via nest surveys. 相似文献