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42.
Masazumi Kayama Kobayashi Makoto Mutsumi Nomura Kaichiro Sasa Takayoshi Koike 《Trees - Structure and Function》2009,23(1):145-157
Sakhalin spruce (Picea glehnii), a native species typically found in northern Japan, has been used in reforestation on hillsides exposed to strong winds.
In the reforestation areas, there are south-facing (S-slope) and northwest-facing slopes (NW-slope). Climatic conditions are
contrasting between the two slopes, with shallower snow cover on the S-slopes. We compared growth responses of the spruce
to micro-environment between the S- and NW-slopes through soil nutrients, needle longevity, water status, photosynthesis,
and nutrients in the needles. These parameters were measured in needles exposed above the snow in winter and in lower needles
protected by snow cover. High-position needles suffered from drought stress, especially in winter, and needles were shed early
in the year on both slopes. Low-position needles did not suffer from drought stress, and maintained a high photosynthetic
rate on both slopes. However, needle longevity was reduced on the S-slope, and concentrations of nitrogen, phosphorus, and
potassium in the needles decreased with needle age. Soil nutrient concentrations were low on the S-slope, which suggests that
the needles on the S-slope may remobilize nutrients from aged needles to younger needles prior to shedding. This characteristic
is probably an adaptation in Sakhalin spruce to poor soil conditions. 相似文献
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Kikuchi I Anbo J Nakamura S Sugai T Sasou S Yamamoto M Oda Y Shiratsuchi H Tsuneyoshi M 《Acta cytologica》2003,47(3):495-500
BACKGROUND: Synovial sarcoma, generally known as a soft tissue tumor, can also occur in the head and neck region, including the thyroid gland. Cytologic findings are important to differentiate the tumor from other types of neoplasms arising in the thyroid gland. CASE: A 60-year-old man complained of hoarseness. A palpable neck tumor was detected, and a computed tomography scan showed a thyroid tumor accompanied by destruction of the thyroid and cricoid cartilage. The results of a preoperative fine needle aspiration biopsy showed numerous spindle cells with pale cytoplasm and oval nuclei with fine, granular chromatin, all of which suggested a medullary carcinoma. The extirpated thyroid tissue weighed approximately 120 g, and a grayish white, elastic, solid tumor (6.8 x 6.5 cm) was present in the left lobe. Histologically, fasciculation of spindle cells that had proliferated solidly and densely was observed. Also, the expression of a chimera gene, SYT-SSX, was detected in the tumor tissue. CONCLUSION: Synovial sarcoma of the thyroid is extremely rare, and its diagnosis by fine needle aspiration biopsy is generally considered very difficult. The detailed cytologic findings observed here might be helpful with the differential diagnosis of thyroid neoplasms. 相似文献
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Study of cognitive function among the Adult Health Study (AHS) population in Hiroshima and Nagasaki 总被引:2,自引:0,他引:2
Yamada M Sasaki H Kasagi F Akahoshi M Mimori Y Kodama K Fujiwara S 《Radiation research》2002,158(2):236-240
Although neuropsychological dysfunction is found among A-bomb survivors exposed in utero as it is among patients who receive central nervous system radiotherapy, neuropsychological examinations have not been conducted on the survivors. Its prevalence may be increased as a result of the increased rate of strokes reported among those exposed to a high radiation dose. In this study, we examined the effects of radiation exposure on cognitive function among adult survivors in the Adult Health Study (AHS). The study subjects were men and women born prior to September 1932 who had undergone biennial examinations during the period 1992-1996 in Hiroshima or 1993-1998 in Nagasaki. We evaluated cognitive performance for 3,113 subjects with the Cognitive Abilities Screening Instrument (CASI), and we examined the relationship between cognitive performance and potentially related factors (sex, age, city where the subjects were exposed, years of education, and radiation dose). In contrast to exposure to radiotherapy, exposure to atomic bomb radiation had no apparent effect on cognitive function. Factors that did affect cognitive function were age, sex, city and years of education. Further investigation, including examination of other neurological functions, is required before a final conclusion regarding radiation-induced neurological dysfunction can be reached. 相似文献
48.
Spontaneous muscle action potentials fail to develop without fetal-type acetylcholine receptors 总被引:6,自引:0,他引:6
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In mammals, two combinations of muscle nicotinic acetylcholine receptors (AChRs) are used: α2βγδ (γ-AChR) or α2βδ (-AChR). After birth, γ-AChRs are replaced by -AChRs (γ/-switch). The two receptors have different conductances and open times. During perinatal period, the long open time γ-AChRs generate random myofiber action potentials from uniquantal miniature end-plate potentials (mEPPs). -AChRs are suitable for strong adult muscle activities. Since the effect of the γ/-switch on neuromuscular development was unclear, despite the many differences in channel characteristics, we carried out this study to generate γ-subunit-deficient mice. Homozygotes born alive survived for 2 days in a stable condition, and were able to move their forelimbs. Endplate AChRs included -subunits, and muscle fibers had multiple neuromuscular junctions. Both pre- and postsynapses were abnormal and spontaneous action potentials generated from mEPPs were totally absent. Results suggest a requirement for γ-AChRs in mediating synaptically-induced action potential activity critical for neuromuscular development. 相似文献
49.
Bratin K. Saha Masazumi Sameshima Fumiko Sameshima David Schlessinger 《In vitro cellular & developmental biology. Plant》1981,17(9):816-824
Summary Activities of three lysosomal enzymes—acid RNase,N-acetyl-β-D-glucosaminidase and acid phosphatase—were determined during the growth cycles of WI-38 and HeLa cells, as well as in radiation-arrested
WI-38 cells. In confluent and growth-arrested cultures of WI-38 cells, the lysosomal RNase increased six- to sevenfold; glucosaminidase,
four- to five-fold; and phosphatase, two- to threefold. In HeLa cells, the lysosomal enzymes also increased in confluent cultures,
but less than twofold; and the RNase level increased only transiently. In both WI-38 and HeLa cells, the rate of RNA breakdown,
also increased as cultured approached confluency. The rate of turnover of RNA, like the level of acid RNase, was higher in
WI-38 cells than in HeLa cells (4 d half-life compared to 8 d).
The increase in acid RNase could be prevented by incubation of cells in NH4Cl, but the rate of turnover in the presence of NH4Cl increased just as much when cells became confluent or stopped growth. The content of acid RNase could be changed more than
10-fold without altering the rate of RNA turnover. It is suggested that the increase in enzyme level is more important for
possible autophagy or increased digestion of engulfed RNA, rather than for normal RNA turnover, when growth stops.
This study was supported by Grant GM-21357 from the National Institutes of Health. 相似文献
50.
Hepatoprotective activity of tocha, the stems and leaves of Ampelopsis grossedentata, and ampelopsin 总被引:8,自引:0,他引:8
Murakami T Miyakoshi M Araho D Mizutani K Kambara T Ikeda T Chou WH Inukai M Takenaka A Igarashi K 《BioFactors (Oxford, England)》2004,21(1-4):175-178
Hepatoprotective effect of the leaves and stems of Ampelopsis grossedentata together with its main constituent, ampelopsin, were examined on D-galactosamine induced liver injury in rats. The diet containing 50% ethanolic extract (1%) and ampelopsin (0.1%) markedly suppressed the increase of LDH, ALT, AST, alpha-tocopherol levels and GSG/GSSH caused by GalN treatment. These results suggested that ampelopsin from Tocha acted to prevent the oxidative stress in vivo that may have been due to active oxygen species formed by a macrophage by the action of GalN. 相似文献